The Diamondbacks and Giants are both making a push for the final Wild Card spot in the National League, meaning this is an important three-game series. In the first game on Monday, the Giants scored 11 runs in a decisive dub.
The NL West frenemies will continue their early-week face-off on Tuesday at 9:45 p.m. ET, as veteran hurlers Zac Gallen (11-13) and Robbie Ray (10-6) take the mound.
Whether you want to attack home runs, hits, or pitcher strikeouts, Diamondbacks vs. Giants provides plenty of opportunities on PrizePicks. Let’s highlight some picks to help you build your Lineups for Tuesday’s MLB DFS slate.
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Diamondbacks vs. Giants Prediction, Preview for 9/9/2025
The Diamondbacks are winning games despite having a brutal schedule down the stretch. Their prior four series were against the Brewers, Dodgers, Rangers, and Red Sox. They managed to go 8-5 during that span.
The Giants just went 4-2 on their recent six-game road trip. In all four of their wins, they scored at least 7 runs. They have a .780 OPS over their last 30 days, compared to their .707 OPS for the season.
Diamondbacks
The Diamondbacks are just 34-39 on the road this season. Their lineup has been the main culprit for their struggles away from Arizona. They have a .735 OPS on the road, compared to a .781 OPS at home.
Giants
The Giants don’t have extreme home and road record splits, going 36-34 in San Francisco and 37-37 on the road. One area that does stand out is their power splits. They've launched just 68 home runs and produced a .384 slugging percentage at home, versus hitting 89 home runs and posting a .401 slugging percentage on the road.
Diamondbacks vs. Giants Picks & MLB DFS
Diamondbacks SP Zac Gallen vs. Giants Projection: 17.5 Pitching Outs
- Gallen has thrown 168 innings this season, the 13th-most in baseball.
- The Diamondbacks have leaned heavily on their 30-year-old vet down the stretch, having him log at least six innings in ten of his last 12 starts.
- Gallen is averaging 94.1 pitches per start for the year.
- The last time he faced the Giants, Gallen logged 101 pitches across seven innings. He finished the game with 10 strikeouts and allowed just 2 runs, 1 of which was unearned.
Giants SP Robbie Ray vs. Diamondbacks Projection: 94.5 Pitches Thrown
- With his 168 2/3 innings pitched this season, Ray is tied for the sixth-highest mark in baseball.
- The lefty tends to have control issues, posting a 9.4% walk rate this season. For his career, he has a 9.9% walk rate.
- Since his control issues can lead to some deep counts, Ray has thrown at least 95 pitches in ten of his last 13 starts. In seven of those outings, he logged at least 100 pitches.
- The two-time All-Star has faced the Diamondbacks two times this season, throwing at least 102 pitches in both matchups.
Diamondbacks C Gabriel Moreno vs. Giants Projection: 1.5 Hits+Runs+RBI
- Moreno doesn’t provide much power, recording a .126 ISO for his career.
- Arizona’s catcher has just a .310 wOBA on the road this season. At home, he has a .367 wOBA.
- Moreno has produced a .343 wOBA and a .179 OPS versus right-handed pitchers, but southpaws have held him to a .310 wOBA and a .159 ISO.
- Oracle Park has not been kind to Moreno. Over 33 career plate appearances, he has a .323 wOBA and a .133 ISO.
Make MLB Picks, Win Cash on PrizePicks
After being sellers at the trade deadline, both the Diamondbacks and the Giants are still in the playoff hunt. Runs might be difficult to come by with Gallen and Ray on the mound. This important matchup also leaves plenty of projections to consider on PrizePicks to win money on MLB.
Just build your MLB Lineup on PrizePicks with your favorite MLB players and win real money if your picks are correct. All you have to do is pick More or Less on at least two player projections — like hits or pitcher strikeouts — to win.
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