Two of the best teams in the NBA meet today as the San Antonio Spurs (59-18) head to Ball Arena to take on the Denver Nuggets (49-28) at 3:00 p.m. ET on Prime Video.
According to PrizePicks Team Picks, the Spurs are 2.5-point favorites on the spread for the third of four head-to-head meetings this season. The season series is currently tied at 1-1, with San Antonio winning game one in Denver before the Nuggets took game two in San Antonio.
Below, we’ll break down our Spurs vs. Nuggets prediction and Saturday NBA picks for PrizePicks. Use PrizePicks NBA to make picks on player projections and win real money if you’re right.
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Spurs vs. Nuggets Prediction, Spread, Over/Under
The Spurs are, undoubtedly, the hottest team in the NBA, winning 11 straight games paired with a 27-2 record over the last 29 games.
Spurs PF/C Victor Wembanyama continues to prove he could be the most dominant player in the NBA. He can single-handedly anchor an entire defense on his own, as seen by him leading the league in blocks with 3.1 in just 29.2 minutes per game.
He's the driving force behind the Spurs returning a 4.34x payout on PrizePicks Team Picks if San Antonio wins the NBA Championship this year. That is the second-shortest return behind the reigning champs, the Oklahoma City Thunder.
The Denver Nuggets are no pushovers either. They have won seven straight games and are nearing full health, with SF Peyton Watson as the only lingering injury.
Nuggets C Nikola Jokic and PG Jamal Murray continue to carry the load. We all know Jokic's dominance; the three-time MVP is averaging a triple-double for the second straight season.
Denver's championship upside may hinge on the play of Murray. He is in the midst of his best season yet; the first-time all-star is averaging a career-high in points (25.6), rebounds (4.4), and assists (7.1) per game.
Spurs vs. Nuggets Spread, Over/Under
The Spurs enter Saturday’s game as 2.5-point road favorites, returning a 1.72x payout on PrizePicks Team Picks if they win outright.
The Nuggets are home underdogs with a 2.08x payout if they win, via PrizePicks Team Picks.
- Spread: San Antonio Spurs -2.5 (1.96x payout)
- Over/Under: 243.5 (1.92x payout on over)
- Game Winner Payout: Spurs 1.72x | Nuggets 2.08x
Team Picks payouts are live as of writing and are subject to change.
Spurs vs. Nuggets Injury Report
Let’s dive into the full Spurs vs. Nuggets injury report for Saturday, via NBA.com.
Spurs Injury Report
- No injuries to report
Nuggets Injury Report
- SF Spencer Jones (hamstring): OUT
- SF Peyton Watson (hamstring): OUT
- PF Zeke Nnaji (hip): OUT
- SG Tim Hardaway Jr. (knee): Probable
Spurs vs. Nuggets Prediction on Spread – 4/4/26
Here are the key stats to know before locking in your Spurs vs. Nuggets prediction on the spread for Saturday, April 4, on PrizePicks.
- San Antonio is 43-33-2 (56.6%) against the spread (ATS) this season, ranking fifth in the league.
- The Nuggets are just 4-4-0 (50%) ATS as a home underdog.
- Despite the Nuggets playing tremendous basketball over their last 10 games, the Spurs still wash them in net rating over that timespan.
- San Antonio has a net rating of +18.1 over their last 10, while the Nuggets are at +8.5, per NBA Advanced Stats.
- Even during the Nuggets' seven-game win streak, the Spurs still have a net rating differential of +10.4 over Denver.
- The Nuggets generate the fewest turnovers per game in the NBA at just 11.8, providing San Antonio the chance for maximum efficiency on offense.
- That concern could widen, as Denver's defense ranks in the bottom 10 in rating (+115.9).
Spurs vs. Nuggets Picks for PrizePicks Today: 4/4/26
Here are two of the top Spurs vs. Nuggets to consider for Saturday, April 4, on PrizePicks. Today’s NBA picks for PrizePicks are headlined by Spurs PF/C Victor Wembanyama and Nuggets C Nikola Jokic.
Spurs PF/C Victor Wembanyama vs. Nuggets Projection: 44.5 Pts + Rebs + Asts
- Wemby could simply be unfadeable right now. The superstar big man has dropped 41 points in back-to-back games and is playing the best basketball of his impressive season.
- He averages 39.2 points, rebounds, and assists (PRA) per game and has upped that average to 42.2 in March.
- Wemby only averages 29.2 minutes per game this season, but it’s reasonable to expect that to exceed 30+ minutes in a meaningful game for playoff seeding.
- As mentioned, the Nuggets' defense has been their weakness all season, ranking 21st in defensive rating.
- They also allow the 10th-most assists per game (27.5).
- Wemby has increased his playmaking in the last couple of months, averaging 3.5 and 3.4 assists per game in February and March.
- While tough to quantify, this game may mean a ton for Wembanyama in his MVP campaign. This is a statement game for the French phenom.
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Nuggets C Nikola Jokic vs. Spurs Projection: 51.5 Pts + Rebs + Asts
- This projection could be a tad low for Jokic, who is averaging 51.5 PRA this season.
- This is a pace-up game for Jokic and the Nuggets, who rank 20th in the league in pace, going against the Spurs, who rank 12th.
- The Spurs rank among the top three defenses in the league and hold opponents to just 45.0% from the field (4th). But it's difficult to not trust Jokic.
- Wemby is a tremendous defender who will likely look to make life difficult for Jokic.
- With that being said, The Joker faced Wemby’s length twice last season, recording 46-9-10 (65 PRA) and 41-18-9 (68 PRA).
Make Spurs vs. Nuggets Picks on PrizePicks
We have a banger on deck with both teams carrying true Western Conference Finals upside. Our Spurs vs. Nuggets picks aren’t the only way hoops fans can get in on the daily NBA action.
You can make your Spurs vs. Nuggets picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
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