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Up to 2000x payouts on your picks.

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Play NFL Fantasy Football with PrizePicks

PrizePicks make it simple for anyone to get in on the action for every NFL game, every day. Just pick “More” or “Less” on your favorite players’ stats — like touchdowns or receptions — and watch the game unfold live. Pick between two and six projections to win up to 2000x your money.

Every game is a new opportunity to win big while enjoying the action.

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Pick Any NFL Stats, Any Time

PrizePicks has all the NFL projections you need for your NFL DFS lineup. You can pick from key NFL stats like:

NBA in-app lineup

Latest from the Playbook

Buccaneers vs. Panthers Prediction, Picks: Baker Mayfield and Rico Dowdle Crush?

Could we see fireworks from Tampa Bay QB Baker Mayfield and Carolina RB Rico Dowdle? And how might it impact our Buccaneers vs. Panthers prediction and picks?

Packers vs. Bears Spread Pick for Pivotal Week 16 NFC North Showdown

Green Bay and Chicago square off in a critical NFC North game, so let’s dive into a Packers vs. Bears spread pick for Week 16’s Saturday contest.

Top NFL Picks, Predictions for Saturday Games in NFL Week 16

Find our top NFL picks and predictions for Saturday games, including Eagles vs. Commanders and Packers vs. Bears in today's PrizePicks cheat sheet.

Eagles vs. Commanders Over/Under Prediction in Saturday NFL Game

Get our Eagles vs. Commanders prediction for the over/under in the Saturday game for NFL Week 16, plus over/under and spread trends for PrizePicks Team Picks.

Packers vs. Bears Prediction, Picks for Saturday Night Football

Green Bay WR Jayden Reed and Chicago RB Kyle Monangai could have massive impact on our Packers vs. Bears prediction and picks for Saturday Night Football.

Eagles vs. Commanders Prediction, Picks: Target Jalen Hurts, More on Saturday

Our Eagles vs. Commanders prediction and picks for Saturday night in Week 16 are headlined by QB Jalen Hurts, RB Saquon Barkley, and QB Marcus Mariota.

Week 16 Start or Sit: Chargers RB Omarion Hampton vs. Cowboys

Leaning on PrizePicks player stat projections, let's make a start 'em, sit 'em verdict on Chargers RB Omarion Hampton for Week 16 vs. the Cowboys.

Buccaneers WR Emeka Egbuka vs. Panthers: Start or Sit Rookie in Week 16?

Buccaneers WR Emeka Egbuka has been one of the best fantasy football WRs this season, but a Week 16 start ‘em, sit ‘em brings his efficiency into question.

NFL Week 16 Picks for PrizePicks, NFL DFS: Time for Justin Jefferson to Shine?

Minnesota Vikings WR Justin Jefferson and Miami Dolphins RB De'Von Achane mark some of the top NFL Week 16 picks for PrizePicks and NFL DFS.

PrizePicks Promo Code: Get $50 Instantly for Jake Paul vs. Anthony Joshua

Use PrizePicks promo code PLAYBOOK to claim $50 instantly in Lineups with the official Jake Paul vs. Anthony Joshua fight promo code.

Vikings RB Aaron Jones vs. Giants: Start or Sit in Week 16?

The Minnesota Vikings' offense lands in Week 16's start or sit debate. What do PrizePicks' projections for RB Aaron Jones indicate about his outlook?

Week 16 Start or Sit: Jets RB Breece Hall vs. Saints

Jets RB Breece Hall finds himself on the start or sit RB list in Week 16. Can PrizePicks' player projections for Hall aid our difficult fantasy decision?

Rams vs. Seahawks Over/Under Pick for Rainy, Windy Thursday Night Game

Get the Rams vs. Seahawks prediction for the over/under on Thursday Night Football in NFL Week 16, plus over/under and spread trends for PrizePicks Team Picks.

Rams vs. Seahawks Prediction, Picks for Thursday Night Football: Revenge Served?

Get an in-depth breakdown and preview for Los Angeles and Seattle, including our Rams vs. Seahawks prediction and picks for Thursday Night Football.

Davante Adams Injury Update: Is Adams Playing Tonight vs. Seahawks?

Get the latest Davante Adams injury update for the Rams vs. Seahawks game in NFL Week 16, plus Puka Nacua and Colby Parkinson stats and a PrizePicks NFL pick.

Who Will Win the Super Bowl 2026? Rams, Broncos SB LX Favorites

Continued solid play from the Rams, Broncos, and Chargers has us all wondering who will win the Super Bowl in 2026?

Rams vs. Seahawks TNF Picks for PrizePicks, NFL DFS: Matthew Stafford, JSN, More

Let's check our Rams vs. Seahawks TNF Picks for PrizePicks, NFL DFS before MVP candidate Matthew Stafford and the NFL's top WR tJaxon Smith-Njigba throw down.

Puka Nacua Stats, Pick vs. Seahawks: Can Rams' WR1 Thrive Without His Star WR2?

With Davante Adams doubtful, the NFL's No. 2 man in receiving yards might be busy on Thursday Night Football. Check our Puka Nacua stats and pick vs. Seahawks.

Join the NFL Action with PrizePicks Today

The PrizePicks NFL board is always fresh, with daily updates to stat projections, players, and exciting new features like Combo Squares, "Demons and Goblins" game feature, and weekly projection discounts. It’s not just hype — PrizePicks is America’s No. 1 Fantasy Sports app, known for top-tier customer service and the most exciting NFL fantasy experience. That’s why our members keep coming back for more NFL fantasy sports.

What is PrizePicks NFL?

PrizePicks is the simplest and best way to play daily fantasy with real money payouts. Just pick more or less on 2-6 player projections to win up to 2000x your money.

Is PrizePicks NFL real money?

Yes, PrizePicks is a real money fantasy sports game. Cash prizes are applied to your PrizePicks account after your Lineup wins, and you can withdraw funds using a debit card, bank account, or PayPal account.

What is the PrizePicks Promo Code for NFL DFS?

If you’re new to PrizePicks, use promo code NFLPicks to get $50 instantly in lineups after you play your first $5 on PrizePicks.

What is a PrizePicks NFL Lineup?

A PrizePicks Lineup is a combination of at least two player projections — such as points, rebounds, assists, and more. You can pick up to six projections in a Lineup to win up to 2000x your money.

What is the PrizePicks NFL payout rate?

With PrizePicks, you can win up to 2000x your money with one Lineup, depending on the number of picks in your Lineup. You can also choose Power Play — where all picks must be correct — or Flex Play — where you can still cash with one or two incorrect picks.

With Demons and Goblins Projections, you can boost your payout, or play a safer Lineup for lower payout rates,

Learn more here about Payout rates on PrizePicks.

Can I combine NFL picks with other sports?

Yes, PrizePicks allows you to mix-and-match player projections from different sports in one Lineup. You can combine player projections from sports like NFL, NBA, MLB, NHL, CFB, CBB, PGA, esports, and much more!

How much money can I win on PrizePicks NFL?

PrizePicks Lineups payout as high as 2000x! The more player projections you include, the higher the payout!

Power Plays, which require you to predict the correct option on every projection in your Lineup, pay out higher than Flex Plays, which still payout with a loss.

How do I get started with PrizePicks NFL?

Go to the PrizePicks app, sign up, and use code NFLPicks to get $50 instantly in lineups when you play your first $5 Lineup!

Is PrizePicks available in my state?

The PrizePicks Real Money Game is available to residents 18+ in AK, AR, CA, DE, FL, GA, IL, IN,KS, KY, ME, MN, MO, NC, ND, NE, NH, NM, OK, OR, RI, SC, SD, TN, TX, UT, VT, WI, WV, WY, and District of Columbia. 19+ in AL, CO, and Canada (excluding Ontario). 21+ for AZ, MA and VA 

PrizePicks Free to Play (Streak) is available to residents 18+ in CT, MD, MI, MS, NJ, NY, OH, PA. 21+ in IA, LA

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