We have a classic Northwest Division rivalry tonight, as the Portland Trail Blazers (40-38) head to Ball Arena to take on the Denver Nuggets (50-28) at 9:00 p.m. ET.
The Nuggets are 7.5-point favorites on the spread on PrizePicks Team Picks for the fourth and final meeting this season between these two teams. Portland aims to tie the season series after winning game one 109-107 and dropping games two and three, 157-103 and 128-112, respectively.
Below, we’ll break down our Trail Blazers vs. Nuggets prediction and Monday NBA picks for PrizePicks. Use PrizePicks NBA to make picks on player projections and win real money if you’re right.
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Trail Blazers vs. Nuggets Prediction, Spread, Over/Under
The Trail Blazers have been cooking recently, winning three straight games and eight of their last 10. They're currently the No. 9 seed in the West but are tied with the Los Angeles Clippers.
Every game is critical to close the season, as leapfrogging L.A. for the No. 8 seed would guarantee Portland at least two chances to secure a playoff berth in the play-in tournament. When playing their best, this is an elite defensive team with enough offense to scare other clubs.
Let the good times roll in Denver. The Nuggets have won eight straight games and are starting to come together health-wise. They're most recently coming off an impressive 136-134 overtime win over the San Antonio Spurs in what was one of the most electric games of the season.
That win ended the Spurs’ 11-game streak and reminded the NBA world that as long as the Nuggets have C Nikola Jokic, they're a threat for the championship. With that being said, Denver's upside could be with the play of PG Jamal Murray.
Murray is in the midst of his best season yet. The first-time All-Star is averaging career highs in points (25.5), rebounds (4.4), and assists (7.2) and is known for playing his best basketball when it matters most.
Trail Blazers vs. Nuggets Spread, Over/Under
The Nuggets enter Monday’s game as 7.5-point home favorites, returning a 1.25x payout on PrizePicks Team Picks if they win outright.
The Trail Blazers are road underdogs with a 3.57x payout if they win, via PrizePicks Team Picks, where you can earn money with your predictions in 35 states!
- Spread: Denver Nuggets -7.5 (1.78x payout)
- Over/Under: 239.5 (1.96x payout on over)
- Game Winner Payout: Trail Blazers 3.57x | Nuggets 1.25x
Team Picks payouts are live as of writing and are subject to change.
Trail Blazers vs. Nuggets Injury Report
Let’s dive into the full Trail Blazers vs. Nuggets injury report for Monday, via NBA.com.
Portland Trail Blazers Injury Report
- PF Jerami Grant (calf): OUT
- G Vit Krejci (calf): OUT
Denver Nuggets Injury Report
- SG Bruce Brown (ankle): Probable
- F Spencer Jones (hamstring): OUT
- PF Zeke Nnaji (hip): Questionable
- F Peyton Watson (hamstring): OUT
Trail Blazers vs. Nuggets Prediction on Spread – 4/6/26
Here are the key stats to know before locking in your Trail Blazers vs. Nuggets prediction on the spread for Monday, April 6, on PrizePicks.
- The Trail Blazers are an above-average covering team, going 42-36 (53.9%) against the spread (ATS).
- The Nuggets, who are known for being a dominant home team, are just 14-15 (48.3%) ATS as a home favorite this year.
- Denver seems to play to its competition level at times. Most recently, it failed to cover at home against the Utah Jazz and Dallas Mavericks and lost on the road to the Memphis Grizzlies.
- The Nuggets have a better net rating than Portland, but only by 5.4 points (+4.8 vs. -0.6).
- Over each team’s last 10 games, it's the Trail Blazers who have the better net rating, ranking fourth in the NBA at +12.9 compared to Denver's +9.3.
- The foundation of Portland’s late-season surge has been incredible defense, leading the NBA in rating (103.7) in the aforementioned 10-game sample.
Trail Blazers vs. Nuggets Picks for PrizePicks Today: 4/6/26
Here are two of the top Trail Blazers vs. Nuggets to consider for Monday, April 6, on PrizePicks. Today’s NBA picks for PrizePicks are headlined by SF Deni Avdija and C Nikola Jokic.
Trail Blazers SF Deni Avdija vs. Nuggets Projection: 40.5 Pts + Rebs + Asts
- Avdija is averaging just 37.6 points, rebounds, and assists (PRA) per game. He cleared this projection in just three of 13 games in March.
- He has only gone above this projection in one of his three matchups against Denver this year.
- This is a tempo-down game for Avdija and the Blazers, facing a Denver team that sits 20th in pace on the season (99.47, per NBA Advanced Stats).
- Avdija is averaging 1.8 fewer points, 0.2 fewer rebounds, and 0.3 fewer assists on the road while shooting 4.2% worse from the field.
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Nuggets C Nikola Jokic vs. Trail Blazers Projection: 51.5 Pts + Rebs + Asts
- Jokic is averaging 51.7 PRA, going over this projection in four of his last six outings.
- The Trail Blazers are seventh in pace, which could create more opportunities to stuff the stat sheet.
- In his last two games against Portland, Jokic went for 22-14-14 (50 PRA) in a 16-point blowout and 32-9-7 (48 PRA) in just three quarters.
- Portland’s two defensive weaknesses are allowing opponents to shoot 35.9% from 3-point range (17th) and giving up 24.4 free throw attempts per game (22nd).
- Jokic is shooting 38.3% from deep and taking a career-high 7.5 free throws each night.
Make Trail Blazers vs. Nuggets Picks on PrizePicks
Wrapping up our Monday basketball slate, we have a fun Western Conference battle between two teams with a lot left to play for. Trail Blazers vs. Nuggets picks aren’t the only way hoops fans can get in on the daily NBA action.
You can make your picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
Stick around with the Playbook for continued NBA predictions, picks, and news.
