Barcelona looks to continue a tremendous run of form at home when they host Newcastle in the second leg of their UEFA Champions League Round of 16 tie on Wednesday, March 18.
The match kicks off at 1:45 p.m. ET on Paramount+ with everything to play for following a 1-1 draw at St. James’ Park last week. Below, we’ll break down our Barcelona vs. Newcastle prediction and picks for Wednesday's Champions League Round of 16 game.
Barcelona have won 15 consecutive home fixtures in all competitions, and have immense attacking depth to call upon.
Can Newcastle withstand the pressure as a road underdog and find a way to hurt Barcelona’s aggressively high defensive line to reach the Champions League quarterfinal stage for just the first time?
Make your Champions League predictions on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Barcelona vs. Newcastle Prediction, Preview for Champions League – Wednesday, March 18
Newcastle looked to have an advantage after the first leg of the Champions League Round of 16 as the sides entered stoppage time at St. James’ Park.
Instead, a Harvey Barnes goal on 86’ was cancelled out by a late penalty from Lamine Yamal to send the tie back to Camp Nou with both sides level, 1-1, on aggregate.
That suits Barcelona just fine, given what they’ve done at home this season. The Catalans have won all 13 matches they have played since the reopening of the renovated Camp Nou, and have won 15 straight matches they’ve hosted in all competitions.
Both sides must overcome significant injuries if they hope to advance.
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Barcelona will be without MF Frenkie de Jong, while their defensive ranks will be hit via the absence of Jules Kounde, Alejandro Balde, and Andreas Christensen.
MF Bruno Guimaraes continues to miss out for the Magpies, robbing them of perhaps their most influential player. Lewis Miley and Fabian Schar are still absent on the defense.
The Magpies did well to limit Yamal’s impact in the first matchup. That will have to continue, given the phenom has either scored or assisted on 12 goals in his last 11 home outings in this competition.
Barcelona’s last six matches have seen them outscore their opponents 17-4, claiming five victories in the process. Newcastle’s recent form has been fairly inconsistent, with three wins and three losses across last seven matches
Newcastle will need to improve on their away defense in the Champions League if they hope to advance.
Aside from their 6-1 win at lowly Qarabag, the Magpies have allowed 6.75 shots on target in four away fixtures. That is nearly twice the amount they’ve conceded in five home fixtures in the competition.
Given Hansi Flick’s attacking options, that could be the difference. Yamal, Raphinha, and Ferran Torres are expected to lead the line for Barcelona, but Robert Lewandowski, Dani Olmo, and Marcus Rashford can also be called upon to influence proceedings — especially if the match heads to extra time.
Barcelona vs. Newcastle Spread, Total Goals, Payouts
Barcelona enters Wednesday’s Champions League game as home favorites, returning a 1.53x payout ($100 entry pays out $153) on PrizePicks Team Picks if the Catalan club wins outright.
Newcastle are long road underdogs with a 4.54x ($454 payout on a $100 entry) payout if the Magpies win, via PrizePicks Team Picks.
Winner Payout: Barcelona – 1.53x | Tie – 4.34x | Newcastle – 4.54x
Spread: Barcelona -1.5 (2.38x Payout)
Total Goals: 3.5 (Over – 1.92x)
Both Teams to Score: Yes 1.44x | No 2.77x
Team Picks data is live at the time of writing and is subject to change. Does not include extra time or penalties.
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Barcelona vs. Newcastle Official Lineups for March 18, 2026
Here are the official Barcelona vs. Newcastle lineups for the Champions League match on Wednesday, March 18. Lineups are not official.
Barcelona XI vs. Newcastle
Joan García; Eric García, Cubarsí, Gerard Martín, Cancelo; Marc Bernal, Pedri; Lamine Yamal, Fermín López, Raphinha; Ferran Torres
Newcastle XI vs. Barcelona
Ramsdale; Trippier, Thiaw, Burn, Hall; Tonali, Joelinton; Ramsey, Elanga, Barnes; Gordon
Barcelona vs. Newcastle Prediction on Total Goals for Champions League Today
Here are the key stats to know before locking in your Barcelona vs. Newcastle prediction on total goals for Wednesday, March 18 in the Champions League. Check out more of our UCL picks and predictions on PrizePicks.
- Barcelona has scored 17 goals in their last six matches in all competitions after a 5-2 win over Seville on Sunday.
- Their nine matches in the Champions League have seen an average of 4.22 goals scored.
- The 1-1 draw in the first leg was the only time this season a Barcelona match has seen fewer than three goals scored in the Champions League.
- Newcastle’s 11 matches in the competition have seen an average of 3.45 goals scored.
- Their five away fixtures in the competition have featured 20 goals in total.
- Newcastle allows nearly twice as many shots on target on the road in the competition as they do at St. James’ Park.
- The Magpies rank fourth in expected goals so far in the Champions League, scoring 27 goals from 24.4 xG.
Barcelona vs. Newcastle Picks for Champions League: Wednesday, March 18
Here are two top Barcelona vs. Newcastle picks on players for Wednesday, March 18 for PrizePicks. Player picks via PrizePicks are headlined by Lamine Yamal and Anthony Gordon.
Barcelona FW Lamine Yamal vs. Newcastle: 4 Shots
- Lamine Yamal averages 3.57 shots in his last 21 starts in all competitions.
- The Barcelona forward averages 3.42 shots per match in his seven Champions League starts.
- Yamal took just 2 shots in the first leg against Newcastle, including the late penalty.
- Newcastle limited Barcelona to only nine shots as a team in the first leg.
- The Spaniard has fewer than 4 shot attempts in four of his last five starts.
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Newcastle FW Anthony Gordon vs. Barcelona: 2 Shots
- Anthony Gordon has taken multiple shots in each of his last six starts in all competitions.
- His 20 shots in those six matches are the most of any Newcastle player in that span.
- The English forward is averaging 3.27 shots per 90 minutes in the Champions League this season.
- Gordon is expected to start at striker, attacking a high Barcelona back line that has conceded 16.56 shots per match in the Champions League.
Make Your Barcelona vs. Newcastle Picks on PrizePicks
Barcelona are 7-1-2 in their last 10 UEFA Champions League second-leg matches, and they're clear favorites to win in regulation on Wednesday, according to PrizePicks Team Picks.
They will have to remain disciplined against a dangerous Newcastle counter-attack, lest they allow the Premier League club to advance past the Round of 16 for the first time in club history.
Barcelona vs. Newcastle is just one of the UEFA Champions League Round of 16 fixtures on offer for you on Wednesday.
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Just pick players, predict More or Less on their projected stats like shots or goals, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
Stick around with the Playbook for continued Champions League predictions, picks, and analysis until a champion is crowned.
