Matchday 3 wraps up Wednesday afternoon with nine more games as Europe’s elite clubs continue their Champions League campaigns.
The slate is headlined by a heavyweight clash between the champions of England and Germany, with Arsenal traveling to the Allianz Arena to take on Bayern Munich in what could be a Champions League Final preview.
Let’s go through the slate and circle our best Champions League predictions today, featuring PrizePicks player projections.
Make your Champions League picks on PrizePicks now!
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Champions League Predictions, Picks for PrizePicks Today – Wednesday, October 21
Each kickoff is listed in Eastern Time. PrizePicks features spreads and winner payouts for every Champions League Matchweek 3 matchup on Wednesday, and each payout is subject to change.
As usual, every Champions League game is accessible via Paramount+.
Payouts below, like 2x, represent real-money multipliers on correct picks on PrizePicks Team Picks at the time of this writing. For example, a $100 entry on Real Madrid to win at a 1.23x multiplier would pay out $123 if you're right.
On PrizePicks, users can predict More or Less for players’ projected stats and earn cash if they’re right. Tonight’s Champions League board is full of options, from projected shots and shots on target to goals, assists, and saves. But which projections stand out among the rest?
Whatchu on? Lock in your Champions League picks on PrizePicks.
Bayern Munich ST Harry Kane Pick vs. Arsenal
Harry Kane Projections via PrizePicks: 1.5 Goals (Demon), 3.5 Shots, 1.5 Shots on Target
- England’s captain faces his country’s champions on Wednesday for the third time since leaving Tottenham — Arsenal's rival. He has scored once in those three meetings, with the goal coming from the penalty spot.
- Kane has now scored or assisted in 10 straight games for both club and country, registering 2 or more goal contributions in eight of those 10 appearances. He will be the focal point of attack with star RW Michael Olise suspended for Wednesday’s game.
- The 33-year-old has 22 goal involvements in 14 games across all competitions this season. Wednesday marks his first action against a Premier League side since facing Arsenal in last season’s Champions League.
- Arsenal are yet to concede in the UCL this season and have allowed just 7 goals across 11 games in all competitions. Bayern managed only 8 total shots in their last meeting with Arsenal — their lowest output of that season.
- Kane has 15 career goals and 3 assists in 22 games against Arsenal. Eight of those goals have come from the penalty spot, and he holds the record for the most goals by any player in the Arsenal-Tottenham rivalry.
Add Harry Kane to your PrizePicks lineup now.
Real Madrid ST Kylian Mbappé Pick vs. RB Leipzig
Kylian Mbappé Projections via PrizePicks: 0.5 Assists (Demon), 32.5 Passes Attempted, 6 Shots
- Mbappé played the 100th Champions League game of his career last week, scoring in the 4-3 comeback win over Roma. He now has a goal in each of the first two matchweeks.
- The French superstar followed up last week’s UCL goal with a brace on Sunday in La Liga, bringing his tally to 11 goals in 11 appearances for Real Madrid across all competitions.
- Last season’s UCL Golden Boot winner leads the competition with 4.0 shots on target per game through the first two matchdays. He has taken 8 shots across those two games, with all 8 requiring a save from the opposing goalkeeper.
- Mbappé has struggled against Leipzig throughout his career, last facing the Bundesliga side as a PSG player in 2021. Across four meetings against them, all as a PSG player, he managed just 1 goal and 3 assists.
- The 27-year-old again leads his team with 4.18 shots per game across La Liga and the Champions League combined. He has now taken 414 total shots in 110 appearances for the club since joining in 2024 — more than any other Real Madrid player in that span.
Pick Kylian Mbappé + Real Madrid to win on PrizePicks.
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Make Champions League Predictions on PrizePicks
With goals flying in through the first two matchweeks, make sure you’re getting in on all the Champions League action on PrizePicks. Wednesday’s games are the last in the competition until early November, with all teams off next week.
Who catches your eye for today’s Champions League schedule? Don’t wait until kickoff — make your Champions League picks on PrizePicks now and earn real money if you’re right.
Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 36 states.
Plus, you can make your Champions League futures predictions, including the tournament winner, all on PrizePicks.
Stay locked in on Playbook for daily soccer predictions, picks, and news all the way through the 2027 Champions League Final.
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