Galatasaray will look to pull off the improbable vs. Liverpool as they head to Anfield for the second leg of their Champions League Round of 16 matchup on Wednesday, March 18.
The Turkish side enters Wednesday’s game with a one-goal advantage on aggregate after defeating Liverpool, 1-0, in last week's first leg.
As a massive favorite to win this game, Liverpool will hope to put last week’s road loss behind them when they host Galatasaray on Wednesday, March 18, at 4:00 p.m. ET on Paramount+.
Below, we’ll break down our Liverpool vs. Galatasaray prediction and Champions League picks for Wednesday's fixture that will decide who moves on to the quarterfinals.
Make your Champions League picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on players, goal totals, and more!
Can Liverpool finally break down Galatasaray’s defense, or will the leaders of the Turkiye Super League defeat The Reds for the third time this Champions League campaign?
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Liverpool vs. Galatasaray Prediction, Picks for Champions League – Wednesday, March 18
Liverpool manager Arne Slot and Co. are still in search of their first goal vs. Galatasaray after over 180 minutes of football between these sides this Champions League campaign.
Gala has won each of the first two contests, 1-0, once in the League Phase, and most recently in the first leg of this Round of 16 tie.
It is important to note that both games played between these clubs this season have been in Turkey. Wednesday afternoon’s matchup will be the first time Liverpool host the Turkish side, and it’ll be in a stadium that has seen the Reds lose just once in their last 12 matches.
Galatasaray will be eager to continue their excellent stretch of form, having won five straight matches. The Turkish giants currently sit atop the Turkiye Super League, and are looking to win the league for the fourth straight year.
Liverpool vs. Galatasaray Spread, Total Goals, Payouts – 3/18/26
Liverpool enters Wednesday’s Champions League Round of 16 game as sizable home favorites, returning a 1.25x payout ($100 entry pays out $125) on PrizePicks Team Picks if they win outright.
PrizePicks Team Picks has the road team, Galatasaray, as massive underdogs, with a 7.69x payout ($100 entry pays out $769) should they find a way to win this game.
- Winner Payout: Liverpool– 1.25x | Tie – 4.34x | Galatasaray– 7.69x
- Spread: Liverpool -1.5 (1.63x Payout)
- Total Goals: 3.5 (Over – 1.81x)
- Both Teams to Score: Yes 1.66x | No 2.08x
Team Picks data is live at the time of writing and is subject to change.
Liverpool vs. Galatasaray Prediction on Both Teams to Score for March 18, 2026
Here are the key stats to know before making your Liverpool vs. Galatasaray prediction on Wednesday, March 18, on PrizePicks.
- Liverpool has outshot Galatasaray 31 to 24 in their two games this season.
- Both teams have created six total big chances in those games.
- The Reds have averaged 60.5% possession vs. Galatasaray this season.
- Gala GK Ugurcan Cakir has made 11 total saves versus Liverpool this season. His 37 saves in the UCL this season are good for fourth-best among all goalkeepers.
- Liverpool has scored in all Champions League games this season except for the two against Galatasaray.
- Liverpool has won just two of their last five games, going 2-2-1 in that span.
- The Reds’ 2-1 loss to Wolverhampton Wanderers, which started this run of form, was the first time a reigning EPL Champion has lost to a team that sits last in the table.
- Galatasaray has conceded just two goals during its five-game win streak.
- Gala manager Okan Buruk’s squad is outscoring opponents, 10-2 in this span.
- Liverpool has not held a clean sheet in five straight games. They are slightly outscoring opponents, 10-7, during that time.
Liverpool vs. Galatasaray Projected XIs
Take a look at the Liverpool vs. Galatasaray projected starting lineups for today's Champions League match. Lineups are not official.
Liverpool Lineup vs. Galatasaray: Projected 4-2-3-1
Goalkeeper: Alisson
Defense: Jeremie Frimpong, Ibrahima Konate, Virgil Van Dijk, Milos Kerkez
Midfield: Ryan Gravenberch, Alexis Mac Allister, Dominik Szoboszlai
Forwards: Mohamed Salah, Hugo Ekitike, Florian Wirtz
Galatasaray Lineup vs. Liverpool: Projected 4-2-3-1
Goalkeeper: Uğurcan Çakır
Defense: Ismail Jakobs, Abdulkerim Bardakci, Wilfried Singo, Sacha Boey
Midfield: Mario Lemina, Lucas Torreira, Gabriel Sara
Forwards: Noa Lang, Victor Osimhen, Barış Alper Yılmaz
Liverpool vs. Galatasaray Picks for Champions League – Wednesday, March 18
Here are two top Liverpool vs. Galatasaray picks to target on players for Wednesday, March 18, for PrizePicks. Player picks via PrizePicks are headlined by Mohamed Salah and the opposing goalkeeper, Uğurcan Çakır.
Liverpool F Mo Salah vs. Galatasaray Pick
Mo Salah Projections via PrizePicks: 0.5 Goal+Assist (Goblin), 2.5 Shots (Goblin), 5.5 Crosses
- Mo Salah has scored two goals in his last five games across all competitions.
- Salah has yet to log one shot versus Galatasaray in his 88 minutes played vs. teh Turkish side this season.
- The Egyptian winger is averaging 1.8 shots per game in his last five across all competitions.
- Look for Salah to be more aggressive with his team trailing by a goal on aggregate entering Wednesday.
- Salah has 29 total crosses in his last five games. The 33-year-old has recorded just two crosses vs. Gala this season.
Galatasaray GK Uğurcan Çakır – 4.5 Goalie Saves
- Uğurcan Çakır has made 27 total saves in his last five games started across all competitions. That is an average of 5.4 saves per game.
- Çakır is averaging 2.8 saves per game in 23 total games played this season. The Turkish goalkeeper has 10 clean sheets in those 23 games.
- Goalkeepers are averaging 4.6 saves per game vs. Liverpool over their last five games.
Make Your Champions League Predictions on PrizePicks
The champions of England will look to defeat the champions of Turkey when they host Galatasaray on Wednesday, March 18, at 4:00 p.m. ET.
Galatasaray will hope to limit Liverpool’s attack one last time in their hopes of advancing to the next round of the UCL.
You can make your Liverpool vs. Galatasaray Champions League picks on PrizePicks and PrizePicks Team Picks to earn real money.
Just pick players, predict More or Less on their projected stats like shots and passes, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.
Stick around with the Playbook for continued soccer and UCL predictions, picks, and analysis.
