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Dodgers vs. Blue Jays Prediction, MLB Pick for Monday, April 6

Los Angeles Dodgers SP/DH Shohei Ohtani hits a home un against the New York Yankees.
AP Photo/Mark J. Terrill

We’ll be treated to a rematch of last year’s MLB World Series when the Los Angeles Dodgers (7-2) and Toronto Blue Jays (4-5) square off on Monday, April 6, at 7:07 p.m. ET.

This is the first contest of a three-game series between the Dodgers and Blue Jays, with Toronto being the home team.

Below, we’ll break down our Dodgers vs. Blue Jays prediction and picks for Monday’s matchup. Make your MLB picks on PrizePicks and earn real money if you’re right, including on game winners, spreads, and totals!

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Dodgers vs. Blue Jays Prediction, Winner Payout, Over/Under

In the opening matchup of the series, Dodgers’ Justin Wrobleski (2.87 xFIP in only 66.2 IP in 2025) and Blue Jays’ Max Scherzer (4.55 xFIP in only 85.0 IP) are slated to be the starters on the bump for Monday’s showdown.

Wrobleski will be making his first start in 2026, but he did log 4.0 IP in relief during his season debut, allowing 4 hits and 3 earned runs. The left-handed hurler also produced a 4.68 xFIP and 3.57 xERA (via FanGraphs) with 2 strikeouts in his short outing out of the bullpen on March 30 against the Cleveland Guardians.

As for Scherzer, he put together a solid performance in his first start of the MLB campaign on March 31 against the Colorado Rockies, recording 4 strikeouts and allowing 1 earned run in 6.0 IP.

Although Scherzer’s fastball velocity (93.1 MPH) was around where it was a season ago, his swinging strike rate sat at 9.6% despite being in a favorable matchup.

Dodgers vs. Blue Jays Winner Payout, Over/Under

The Blue Jays enter Monday’s game as home underdogs, returning a 2.17x payout on PrizePicks Team Picks if they win outright.

The Dodgers are road favorites with a 1.63x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.

  • Spread: Dodgers -1.5 (2.04x payout)
  • Over/Under: 8.5 Runs (1.75x payout on Over)
  • Game Winner Payout: Blue Jays 2.17x | Dodgers 1.63x

Team Picks data is live at the time of writing and is subject to change.


Dodgers vs. Blue Jays Prediction to Win – 4/6/26

Here are the key stats to know before locking in your Dodgers vs. Blue Jays prediction on the winner for Monday, April 6, on PrizePicks.

  • According to Baseball Savant, Scherzer ranked in the 20th percentile in xERA (4.64), 41st percentile in xBA (.245), and second percentile in barrel rate (12.4%) last season.
  • On the other hand, Wrobleski was in the 75th percentile in xERA (3.43), 80th percentile in strikeout rate (27.1%), and 98th percentile in barrel rate (3.8%) a season ago.
  • Against right-handed pitching in 2025, the Dodgers posted the fourth-best wRC+ (114), third-best wOBA (.332), fourth-best ISO (.187), and 13th-lowest strikeout rate (21.8%), per FanGraphs.
  • While LA’s bullpen is 10th in xERA (3.30) and eighth in HR/9 (0.55) to begin the 2026 campaign, Toronto’s relievers are 18th in xERA (4.35) and 17th in HR/9 (1.22).
  • After going 38-32 outright as road favorites in 2025, the Dodgers are a perfect 3-0 in the same split to start this season.
  • The Blue Jays enter Monday’s bout on a four-game losing streak, with all four losses coming against the Rockies and Chicago White Sox.

Dodgers vs. Blue Jays Picks for PrizePicks Today: 4/6/26

Here are the top Dodgers vs. Blue Jays picks to target for Monday, April 6. Today’s MLB picks for PrizePicks are headlined by Dodgers DH Shohei Ohtani and Blue Jays 2B Ernie Clement.

Dodgers DH Shohei Ohtani vs. Blue Jays Projection: 2.5 Hits + Runs + RBIs

  • Following a slow start to the year, Shohei Ohtani has multiple hits in three straight outings. Ohtani has also totaled 3 runs, 2 HRs, and 6 RBIs across his last three games.
  • When facing right-handed pitching in 2025, Ohtani tallied a 186 wRC+, .438 wOBA, and .378 ISO, via FanGraphs.
  • At the same time, Scherzer coughed up a 5.14 xFIP, 1.28 WHIP, and 2.45 HR/9 to lefties last year. Against righties, he surrendered a 3.81 xFIP, 1.31 wHIP, and 1.45 HR/9.

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Blue Jays 2B Ernie Clement vs. Dodgers Projection: 1.5 Hits + Runs + RBIs

  • During the 2025 season, Wrobleski notched a 3.04 xFIP, 1.39 WHIP, and .375 BABIP to right-handed batters. Comparatively, he had a 2.47 xFIP, 0.87 WHIP, and .220 BABIP against the opposite stance.
  • Ernie Clement achieved a 146 wRC+, .379 wOBA, and .223 ISO when facing lefties last year, compared to a 75 wRC+, .275 wOBA, and .073 ISO against righties.
  • Clement has at least 1 hit in seven of his nine starts to begin the season, and he’s gotten multiple hits in four of those outings.

Make Dodgers vs. Blue Jays Picks on PrizePicks

While it’s still too early to tell which teams will be competing for the title, the Dodgers and Blue Jays are trending in different directions recently. Can Toronto bounce back at home and get some revenge against Los Angeles following their World Series defeat in 2025?

You can make your Dodgers vs. Blue Jays picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states

Stick around with the Playbook for continued MLB predictions, picks, and news throughout the 2026 season.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Skyler Carlin is an experienced writer with nearly 10 years of experience writing and editing NFL, NBA, MLB, CFB, CBB, & soccer content for FanDuel Research & USA Today. When he’s not writing, he enjoys cooking, watching movies, & playing video games.

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