A pair of National League West rivals square off tonight at 9:40 p.m. EST at Petco Park, as the slumping San Francisco Giants — who are 2-8 in their last 10 games — stare down the San Diego Padres for the 12th time this season. The Padres hold an 8-3 series lead.
We've got today’s top Padres vs Giants predictions below, including MLB picks for Rafael Devers and Landen Roupp for Wednesday, August 20. There's no better time than now to make your MLB predictions on PrizePicks.
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Padres vs Giants Prediction, MLB Picks Today
Here are the top Padres vs. Giants predictions and picks today, including MLB DFS picks on PrizePicks today. Use this MLB analysis to make your MLB predictions on PrizePicks MLB on Wednesday, August 20. Click to read more about each pick.
- Giants P Landen Roupp – 3.5 Pitcher Strikeouts
- Padres P JP Sears – 4.5 Hits Allowed
- Giants DH Rafael Devers – 6.5 Hitter Fantasy Score
- Giants OF Ramón Laureano – 1.5 Hits+Runs+RBIs
Giants P Landen Roupp Projection: 3.5 Pitcher Strikeouts

- In his last 37 plate appearances, Landen Roupp is surrendering a 17% barrel rate, 40% hard-hit%, and an alarming 43% fly ball rate.
- Over the full season across 463 plate appearances, Roupp still holds a near-10% barrel rate and 43% hard-hit%.
- Roupp has surpassed this projection in four out of his last five games.
Padres P JP Sears Projection: 4.5 Hits Allowed

- Across his last 61 plate appearances, JP Sears has allowed a near 12% barrel rate, 57% hard-hit%, and 38% fly ball rate.
- Sears has given up 14 earned runs over his last 18 innings pitched.
- The San Francisco Giants, in 917 plate appearances against left-handed pitching this season, own a .295 BABIP and a 28% fly ball rate.
Giants DH Rafael Devers Projection: 6.5 Hitter Fantasy Score

- Against left-handed pitching this season in 187 plate appearances, Rafael Devers owns a 30% fly ball rate, 66% hard-hit%, and a 13% barrel rate, resulting in a .318 BABIP.
- In his career against JP Sears, Devers is 2-for-9 with one extra-base hit.
- In the month of August, Devers is hitting .262 with 5 home runs, showing continued power from the left side.
- Devers has surpassed this fantasy score projection twice in his last three games
Giants OF Ramón Laureano Projection: 1.5 Hits+Runs+RBIs

- This season across 232 plate appearances against right-handed pitching, Ramón Laureano owns a 30% fly ball rate, 50% hard-hit%, and a 12% barrel rate.
- Over his last 69 plate appearances, Laureano has elevated his production with a 34% fly ball rate, 55% hard-hit%, and a near 15% barrel rate, leading to a .432 BABIP.
- Laureano is averaging 1.8 hits+runs+RBIs across his last five games.
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The Padres are just two games behind the Dodgers for the lead in the NL West, while the Giants are fighting to keep their playoff hopes alive.
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