The Wednesday MLB slate showcases a full slate of 15 games, including a key NL Central matchup. Headlining MLB DFS today, the Cubs battle the Brewers at Wrigley Field at 8:05 p.m. ET, as Chicago seeks a third straight victory.
Welcome to Wednesday’s MLB DFS Picks, where we’ll break down today’s MLB games and give you the best MLB DFS picks for PrizePicks for August 20, including pitcher strikeout projections and hitter projections to target today.
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Let’s break down some of the best MLB picks to target for the Wednesday MLB DFS slate on PrizePicks.
MLB DFS Picks on PrizePicks: Wednesday, 8/20
Here are some of the top MLB DFS picks and predictions on PrizePicks today. Use this analysis to help you build a stacked MLB Lineup on PrizePicks for Wednesday, August 20. Click each pick to read more.
- Braves 1B Matt Olson — 7.5 Hitter Fantasy Score
- Twins CF Byron Buxton — 1.5 Total Bases
- Mets P Kodai Senga — 5 Strikeouts
- Reds P Nick Martinez — 4 Strikeouts
Braves 1B Matt Olson Projection: 7.5 Hitter Fantasy Score

- Braves 1B Matt Olson is coming off a 4-of-5 performance in Tuesday’s comeback victory over the White Sox.
- Olson finished with 22 fantasy points last night, marking his fourth game of at least 8 fantasy points in the past five contests.
- Olson is riding a six-game hitting streak, but has hit only 1 home run in August.
- Chicago P Martin Perez takes the mound tonight, and Olson is 2-of-13 lifetime against the southpaw.
- Although Olson is batting .347 this month, he has driven in just 4 runs in 18 games.
Twins CF Byron Buxton Projection: 1.5 Total Bases

- Twins CF Byron Buxton has not managed a hit in three of the last four games.
- During this stretch, Buxton’s only strong performance came in Sunday’s victory over the Tigers. Buxton compiled 3 hits, but is batting .219 in August.
- Buxton finished with less than 1.5 total bases in 10 of the past 12 games.
- Buxton produced the highest hard-hit rate of his career at 54.3%.
- Athletics P J.T. Ginn has allowed a hard-hit rate of 48.1%, which is in the 6th percentile of MLB.
Mets P Kodai Senga Projection: 5 Strikeouts

- Mets P Kodai Senga finished with 5 or less strikeouts is seven of his last eight road starts.
- Senga’s strikeout rate in his 2023 rookie season was a solid 29.1%, but that number has dipped to 22.9% here in 2025.
- The right-hander finished with 5 strikeouts in each of his two starts against Washington this season.
- The two Nationals’ batters with the highest strikeout rates are LF James Wood (30.2%) and 3B Paul DeJong (29.1%). Wood and DeJong have struck out twice each against Senga in their career.
- Senga’s forkball is his most reliable pitch, producing 64 strikeouts and an opposing batting average of .118.
Reds P Nick Martinez Projection: 4 Strikeouts

- Reds P Nick Martinez picked up 1 strikeout in his last start against Milwaukee.
- Martinez posted 4 or more strikeouts in his previous four outings.
- Angels OF Mike Trout has struck out twice in 22 at-bats against Martinez in his career.
- Among Cincinnati starting pitchers, Martinez owns the lowest strikeout rate at 17.1%.
- Martinez’s strongest strikeout pitch is his changeup, which is responsible for 26 of his 98 strikeouts.
Make MLB DFS Picks on PrizePicks
There’s exciting action on Wednesday’s MLB slate, capped off by 10 night matchups after a full day of games. With 15 MLB games on tap, now is time to build your MLB Lineup on PrizePicks.
Just pick More or Less at least two MLB player stat projections to build your Lineup on PrizePicks. Use the players above to build your Lineups around, or use a 6-Pick Lineup to reach up to 2000x payouts.
Check out the Playbook for more MLB DFS picks and analysis all the way through the season.