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From Week 1 to the Super Bowl, get NFL predictions on winners, spreads, and totals, plus expert picks on players for NFL DFS and start/sits on PrizePicks.

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Rams QB Matthew Stafford attempts a throw in a game vs. the Seahawks.

49ers vs. Rams Pick Against the Spread – 9/10/26

10 September 2026

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By Kevin Rogers

Featured Articles

Rams QB Matthew Stafford attempts a throw in a game vs. the Seahawks.

49ers vs. Rams Prediction, Pick Against the Spread for NFL Week 1 – 9/10/26

By Kevin Rogers • September 10, 2026

Packers RB Josh Jacobs celebrates following a touchdown vs. the Lions.

Josh Jacobs News: Packers RB Pleads No Contest, Leading to Potential Suspension

By Riley Thomas • September 10, 2026

Los Angeles Rams WR Puka Nacua celebrates during an NFL game against the New England Patriots.

Best 49ers vs. Rams Touchdown Scorer Picks for NFL Week 1 Thursday Night Football

By Anthony Blanco • September 10, 2026

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The Latest NFL Articles

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49ers TE George Kittle celebrates a first down in a game vs. the Titans.

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New York Giants TE Isaiah Likely runs a route during a summer practice.

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Seattle Seahawks quarterback Sam Darnold, center, is sacked by New England Patriots linebacker Dre'mont Jones, left, as Seattle Seahawks linebacker Connor O'Toole is at right, during the first half of an NFL football game, Wednesday, Sept. 9, 2026, in Seattle.

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New England Patriots wide receiver A.J. Brown (1) laughs with teammates during the team's NFL football training camp. Brown suffered an injury in the Patriots' season opener on Wednesday, Sept. 9, 2026.

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Chicago Bears WR Rome Odunze celebrates a touchdown during the second half of an NFL football game against the Las Vegas Raiders Sunday, Sept. 28, 2025, in Las Vegas.

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Washington Commanders WR Terry McLaurin reacts to a TD scored against the New Orleans Saints.

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New England Patriots RB TreVeyon Henderson runs during an NFL game against the New York Jets.

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Chicago Bears RB D'Andre Swift runs during an NFL game against the Baltimore Ravens.

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Cincinnati Bengals wide receiver Ja'Marr Chase (1) celebrates a touchdown in the first half during an NFL football game.

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Texans EDGE Will Anderson Jr. celebrates following a stop vs. the Colts.

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New England Patriots quarterback Drake Maye (10) throws a pass against the Carolina Panthers during the first half of an NFL football game.

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Titans WR Carnell Tate makes a catch during practice in the offseason.

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Indianapolis Colts TE Tyler Warren during an NFL game against the Tennessee Titans.

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Bears WR Luther Burden III runs on the fielid in a game vs. the Eagles.

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