Saquon Barkley Injury Update: Is Eagles RB Playing in Week 7?

October 22, 2026

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NFL
AP Photo/Matt Slocum
Eagles RB Saquon Barkley runs with the ball during the first half of a game vs. the Rams.

Philadelphia Eagles RB Saquon Barkley suffered a hamstring injury in Week 4 against the Los Angeles Rams and hasn’t played since. As the Eagles prepare for Week 7, is he in danger of missing Monday Night Football?

The Eagles host the Dallas Cowboys for Monday Night Football at 8:15 p.m. ET on ESPN and ABC on Monday, October 26. With Barkley failing to practice last week, what are his chances of returning from injury?

Below, we’ll analyze the latest Saquon Barkley injury update, his latest practice status, and how his injury impacts fantasy football and Cowboys vs. Eagles picks for PrizePicks. 

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Saquon Barkley Injury Update: Will Barkley Play in Week 7 vs. Cowboys?

Barkley has been sidelined for the Eagles’ last two games, which were losses to the Jacksonville Jaguars and Carolina Panthers. 

However, it seems like Barkley could be back in the lineup for Week 7. Barkley is expected to practice today and is in line to play vs. the Cowboys, according to NFL Network’s Mike Garofolo. 

Barkley’s potential return could provide a big boost to a struggling Eagles offense that’s now without starting quarterback Jalen Hurts. Below, we’ll dive into the impact Barkley could make for Week 7 in terms of fantasy football and Eagles picks for PrizePicks. 


Eagles Fantasy Football Outlook If Saquon Barkley Is Out

As we mentioned above, Barkley appears to have the go-ahead to play vs. the division rival Cowboys on Monday Night Football. The 6-foot, 233-pound Barkley is a three-time Pro Bowler and was a key contributor for the Eagles’ Super Bowl LIX title. 

From a fantasy football perspective this season, Barkley has had minimal impact so far. He has 190 yards from scrimmage (182 rushing, 8 receiving) and has yet to score a touchdown. Yet, Barkley has been efficient with yards per carry at a clip of 5.1 yards, including a season-long 42-yard attempt.

The Eagles have been in flux with their backfield, which should give Barkley a large workload if he plays vs. the Cowboys.

With Barkley out, Dameon Pierce had 35 rushing yards and a TD in the loss to the Panthers. RBs Tank Bigsby and Will Shipley are on the IR. Eagles RB Carson Steele was waived on Tuesday. For the practice squad, RB Elijah Mitchell got signed while RB Ian Wheeler was waived. 

The Eagles rank 29th in rushing yards per game (82.2). However, if Barkley is active, he could have plenty of opportunities for big plays vs. the Cowboys’ defense that ranks last in rushing yards per game (149.8). 

Barkley’s availability will ultimately be determined by how he responds to Thursday’s practice and the progress he’s able to achieve. If he gets cleared, there’s the potential for a strong return in primetime. 

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Saquon Barkley has missed the past two games with a hamstring injury. If he returns in Week 7, the Cowboys may present a solid matchup. If not, RB Dameon Pierce figures to maintain a busy role for the Eagles in a division rivalry bout. 

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