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Week 7 is jam-packed with notable matchups across the NFL. Over on PrizePicks, fans can get in on the action with endless options for player picks, including pass yards, rush yards, receptions, and more.
With plenty of stars in action in Week 7, which players stand out across Sunday’s contests?
Below, we'll bring you our top NFL DFS picks for PrizePicks, where you can predict More or Less on player stats to earn real money if you're right!
Make your Week 7 NFL predictions and picks on PrizePicks!
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Week 7 NFL DFS Picks for PrizePicks – Sunday, October 25
Here are the top Week 7 NFL DFS picks to target on PrizePicks for Sunday, October 25.
Today’s NFL picks include Jaylen Warren, Matthew Golden, Kyler Murray, Ollie Gordon II, and Malik Nabers.
Stats in this article are courtesy of PFF or SumerSports unless stated otherwise.
Steelers RB Jaylen Warren vs. Saints: 63.5 Rush Yards
- RB Jaylen Warren had 93 or more rushing yards in three straight starts before finishing with only 50 in Week 6 against the Tampa Bay Buccaneers.
- The Buccaneers’ defense is sixth in rushing EPA (-0.18) and rushing success rate allowed (35.7%).
- RB Rico Dowdle is questionable for the Pittsburgh Steelers in Week 7 against the New Orleans Saints.
- The Saints’ defense is dead last in rushing EPA (-0.00) and rushing success rate allowed (48.1%).
Pick Jaylen Warren + Steelers to win on PrizePicks!
Packers WR Matthew Golden vs. Lions: 75.5 Rec Yards
- WR Matthew Golden has tallied at least 95 receiving yards in four of his first six games in 2026, including three of his last four.
- While WR Christian Watson also has a favorable matchup against the Detroit Lions, Golden leads the Green Bay Packers in targets (44), receptions (24), and yards per route run (2.39) since Week 2.
- Among the 54 WRs in the NFL with 25+ targets entering Week 7, Golden has the fourth-most yards per reception (16.7) on the fifth-highest average depth of target (14.9).
- Detroit’s defense is 28th in dropback EPA (0.26) and 30th in dropback success rate allowed (52.7%).
Pick Matthew Golden + Packers to cover the spread on PrizePicks!
Vikings QB Kyler Murray vs. Colts: 205.5 Pass Yards
- QB Kyler Murray has aired it out for at least 229 yards in back-to-back starts.
- The Minnesota Vikings are coming out of their bye week, giving Murray an opportunity to get more comfortable in Kevin O’Connell’s offense.
- Murray figures to have his offense at full strength, including both WR Justin Jefferson and TE T.J. Hockenson being available.
- Along with giving up the third-most yards per completion (11.8), the Indianapolis Colts’ defense is 20th in dropback EPA allowed (0.08).
Pick Kyler Murray + Vikings to win on PrizePicks!
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Dolphins RB Ollie Gordon II vs. Jets: 52.5 Rush Yards
- RB Ollie Gordon II has rushed for 88+ yards in back-to-back starts, including against a stout Minnesota run defense that is first in rushing success rate allowed (28.0%).
- Gordon has gotten 17 or more carries in two of his last three games, and backup RB Jaylen Wright is questionable to play.
- Among the 53 RBs with 25 or more carries, Gordon has the seventh-most yards per attempt (5.0), 12th-most yards after contact per attempt (3.38), and 13th-most runs of 10-plus yards (8).
- The New York Jets’ defense is 26th in rushing success rate allowed (42.5%), and the Dolphins’ offense is 27th in neutral pass rate (47.1%).
Pick Ollie Gordon II + Dolphins to cover the spread on PrizePicks!
Giants WR Malik Nabers vs. Texans: 5.5 Recs
- WR Malik Nabers has at least 6 receptions in three straight games, including back-to-back outings with 11 or more catches.
- The New York Giants’ passing game saw a slight boost with QB J.J. McCarthy replacing QB Jameis Winston, and it will be McCarthy starting in Week 7.
- On the road against the Houston Texans, the Giants are expected to play from behind, leading to more passing opportunities.
- Nabers leads New York’s offense in target share (29.6%) through the team’s first six games.
Pick Malik Nabers + Giants to cover the spread on PrizePicks!
Make Week 7 NFL Picks on PrizePicks
It can be beneficial to target favorable matchups when considering player picks each week. Of the available player pick options on PrizePicks, Warren, Golden, Murray, Gordon, and Nabers are in solid spots in Week 7.
Ahead of Sunday’s action, it's time to lock in your NFL picks on PrizePicks. Just pick your players, predict More or Less on their stats, and cash in on your predictions when you're right.
With PrizePicks Team Picks, make your predictions on game winners, spreads, and over/unders — or combine one with players for even higher payouts.
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