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Guardians OF Steven Kwan rounds third base following a home run vs. the Twins.

Guardians vs. Red Sox Prediction, MLB Picks – 9/22/26

22 September 2026

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By Mike Barner

Featured Articles

Guardians OF Steven Kwan rounds third base following a home run vs. the Twins.

Guardians vs. Red Sox Prediction, MLB Picks for Tuesday, September 22

By Mike Barner • September 22, 2026

Braves RF Ronald Acuna Jr. hits and watches his solo home run vs. the Guardians.

Best MLB Home Run Picks Today – Tuesday, September 22

By Skyler Carlin • September 22, 2026

Toronto Blue Jays 3B Kazuma Okamoto hits a ball during an MLB game vs. the San Francisco Giants.

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By Kenyatta Storin • September 21, 2026

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The Latest MLB Articles

Brewers SP Jacob Misiorowski reacts during a game vs. the Padres.

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Rays 3B Junior Caminero rounds the bases following a home run vs. the Twins.

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Philadelphia Phillies SP Aaron Nola throws a pitch during an MLB game against the Texas Rangers.

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New York Mets LF Juan Soto hits the ball during an MLB game against the Washington Nationals.

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San Diego Padres RF/2B Fernando Tatis Jr. during an MLB game against the Philadelphia Phillies.

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Detroit Tigers LF Riley Greene looks on during an MLB game against the Los Angeles Angels.

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Toronto Blue Jays DH George Springer before an MLB game vs. the Chicago White Sox.

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New York Yankees 1B Luis Garcia Jr. hits a home run during an MLB game vs. the St. Louis Cardinals.

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Cleveland Guardians OF Jo Adell runs during an MLB game against the Chicago White Sox.

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Braves 1B Matt Olson watches his solo home run vs. the Mariners.

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White Sox 3B Miguel Vargas celebrates as he rounds the bases following a home run in the MLB All-Star game.

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Rays 3B Junior Caminero watches his three-run home run vs. the Athletics.

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Atlanta Braves RF Ronald Acuña Jr. during an MLB game against the Philadelphia Phillies.

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Cleveland Guardians OF Steven Kwan rounds the bases during an MLB game against the Minnesota Twins.

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Colorado Rockies C Hunter Goodman looks on during an MLB game against the Los Angeles Dodgers.

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Padres OF Jackson Merrill rounds the bases following a home run vs. the Giants.

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Reds SS Elly De La Cruz celebrates with 1B Sal Stewart in a game vs. the Tigers.

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Texas Rangers SP Cody Bradford throws a pitch during an MLB game against the Athletics.

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Minnesota Twins SP Zebby Matthews throws a pitch during an MLB game against the Chicago White Sox.

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Rays SP Freddy Peralta winds up for a pitch in his start vs. the Tigers.

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Brewers SP Jacob Misiorowski delivers a pitch in his start vs. the Angels.

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Phillies DH Kyle Schwarber and 1B Bryce Harper following a home run vs. the Giants.

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St. Louis Cardinals 1B Alec Burleson hits a home run during an MLB game against the Philadelphia Phillies.

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San Francisco Giants 1B Rafael Devers celebrates during an MLB game against the Miami Marlins.

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