Yankees vs. Rays Prediction, MLB Picks for ALDS Game 2 – Monday, October 5

The New York Yankees and the Tampa Bay Rays will clash in Game 2 of the American League Division Series on Monday, October 5, at 8 p.m. ET on truTV. Ahead of the first pitch, the Yankees are a road favorite with a 1.75x payout to secure a victory on PrizePicks.

Entering Game 2, Tampa Bay is winning the race to three wins in the ALDS after winning Game 1 by the score of 1-0. It was SP Drew Rasmussen who was dealing in Saturday’s series opener, striking out 10 batters while giving up just 1 hit in 8.0 IP.

Below, we'll break down our Yankees vs. Rays prediction and picks for Monday’s MLB contest, including the run line, over/under, and key player picks for PrizePicks.

Make your Yankees vs. Rays picks for the ALDS on PrizePicks now!

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Yankees vs. Rays Prediction, Winner Payout, Over/Under for ALDS Game 2 – Monday, October 5

For the second game of the series, Yankees SP Cam Schlittler (2.86 xFIP across 193.2 IP) and Rays SP Freddy Peralta (4.37 xFIP across 169.0 IP) will face each other on the mound.

During the regular season, Schlittler was one of the most dominant pitchers in baseball, ranking in the 93rd percentile in xERA (2.85) and 86th percentile in xBA (.206), per Baseball Savant. In Schlittler’s first start of this postseason against the Boston Red Sox, he racked up 10 Ks while allowing only 2 hits in 6.1 IP.

On the other hand, Peralta wasn’t consistent in the regular season, though he was still above average with a 62nd-percentile xERA (3.84) and 59th-percentile in xBA (.234). He was acquired by the Rays at the deadline as depth, but Tampa Bay’s bullpen will be fresh after Rasmussen's Game 1.

After scoring 9 runs in each of their two wins over the Red Sox in the Wild Card Round, the Yankees were unable to get on the scoreboard in the series opener against the Rays. The absence of RF Aaron Judge is certainly being felt.

It was a third-inning home run from 1B Jonathan Aranda off SP Gerrit Cole that made the difference for the Rays in Game 1.

Ahead of Monday’s matchup, Tampa Bay returns the third-lowest payout to win the World Series (5.88x) on PrizePicks, while New York has the fourth-lowest payout (7.69x) in the same market among the teams remaining in the postseason.

Yankees vs. Rays Winner Payout, Over/Under – Monday, October 5

The Yankees enter Monday’s game as a road favorite against the Rays, returning a 1.75x payout if they win outright on PrizePicks.

Here are the full payouts for the Yankees vs. Rays game on PrizePicks.

Make your Yankees vs. Rays prediction on spread or over/under on PrizePicks now!

Team Picks data is live at the time of writing and is subject to change.

Yankees vs. Rays Prediction on Winner for ALDS Game 2 – 10/5/26

Here are the key game stats and trends behind our Yankees vs. Rays prediction on the winner for Monday, October 5.

• This will be Schlittler’s fourth meeting against the Rays this season; he’s totaled 5 ER and 21 Ks in 16.0 IP across the first three meetings.
• Schlittler hasn’t given up more than 1 ER in 10 straight starts (including playoffs).
• Additionally, Schlittler possessed a 14-6 record in the regular season, and his last loss he was credited with occurred on July 19 against the Los Angeles Dodgers.
• While Peralta finished the season strong, he surrendered a 1.35 WHIP and 1.42 HR/9 to lefties compared to a 1.29 WHIP and 0.88 HR/9 to righties, per FanGraphs.
• In Game 1 of the ALDS, New York trotted out eight left-handed hitters and 1 right-handed hitter against Rasmussen.
• Although the postseason can bring the best out of teams, Tampa Bay has the 13th-worst wRC+ (97), 11th-worst wOBA (.310), and 11th-worst ISO (.148) since the start of September.

Lock in your Yankees vs. Rays prediction on PrizePicks now.

Yankees vs. Rays Picks, Player Stats for ALDS on PrizePicks: 10/5/26

Here are the top Yankees vs. Rays picks to target on Monday, October 5. Today’s MLB picks for PrizePicks include Ben Rice and Freddy Peralta.

Yankees DH Ben Rice vs. Rays: 5.5 Hitter Fantasy Score

• Rice has crushed righties to the tune of a 165 wRC+, .407 wOBA, and .305 ISO in 2026.
• While Rice has better metrics at home, he still has a 143 wRC+, .376 wOBA, and .252 ISO on the road this season.
• Since the start of September, Rice owns a 195 wRC+, .450 wOBA, and .272 ISO.

Add Ben Rice + Yankees to win to your PrizePicks lineup now.

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Rays SP Freddy Peralta vs. Yankees: 3.5 Hits Allowed

• Peralta has given up at least 4 hits in three of his last four starts, and he failed to pitch into the sixth inning in two of those.
• Whether it was with the New York Mets or Rays, Peralta has permitted 4+ hits in 24 of his 32 starts in 2026.
• Across his 32 starts, Peralta is in just the 41st percentile in strikeout rate (21.4%) and 40th percentile in ground ball rate (40.4%).
• Once again, the Yankees are likely going to deploy at least eight left-handed hitters on Monday, and Peralta is allowing a .293 BABIP in that split (compared to a .278 BABIP against right-handed hitters).

Add Freddy Peralta + Rays to cover the spread to your PrizePicks lineup now.

Make Yankees vs. Rays Picks on PrizePicks

The Yankees are looking to avoid falling to 0-2 in the ALDS against the Rays on Monday. With Schlittler on the mound against Peralta, New York has a major advantage on the mound in Game 2.

Don’t wait until the first pitch — make your Yankees vs. Rays picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on MLB game winners, spreads, and over/unders, now available in 36 states.

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