NFL DFS Cheat Sheet for PrizePicks: Week 11
NFL Week 11 is here, and we’ve got a full NFL DFS breakdown below to help you quickly discover the top NFL DFS picks and matchups to target for the Week 11 main slate.
From WR vs. CB matchups, OL vs. DL matchups, and TD scorer predictions — the NFL PrizePicks Cheat Sheet your guide to help you build your winning Lineups in Week 11.
This week’s matchups are stacked with excitement between top teams. We’ll spotlight games to target, high-upside matchups, and TD scorer picks to give your PrizePicks Lineup an edge.
Don’t miss out — check the PrizePicks NFL board, lock in your picks, and get in on all of the Week 11 action. If you’re looking for more picks and injury news, check out the Week 11 Picks for a position-by-position breakdown.
NFL Week 11 Cheat Sheet for PrizePicks
Find the top picks, matchups to target, and TD scorer predictions for NFL DFS Week 11 below in the PrizePicks Cheat Sheet.
- Week 11 Best Games to Target
- Week 11 Best OL/DL Matchups to Target
- Week 11 WR/CB Matchups to Target
- Week 11 Best TD Scorer Picks
Top Games to Target in Week 11 for DFS
Ravens vs. Steelers — 1 p.m. ET
The Steelers and Ravens face off in a crucial AFC North matchup with significant playoff implications. Ravens QB Lamar Jackson has been electric this season, surpassing his passing yardage projection of 240.5 yards in 8 of 10 games. Against Pittsburgh, Jackson has hit this mark in one of his last two games, narrowly missing in the other with 236 yards.
Pittsburgh’s defense, while strong overall, has struggled against the pass, ranking outside the top 20 in passing yards allowed per game.
This creates a dilemma for the Steelers, as they must also account for Baltimore’s formidable rushing attack led by Jackson and RB Derrick Henry. The Steelers’ inability to simultaneously defend the pass and stack the box could leave them vulnerable to explosive plays.
Since returning from injury, Steelers QB Russell Wilson has revitalized Pittsburgh’s offense, providing a legitimate passing threat. Averaging nearly 250 passing yards per game, Wilson has gone more than this projection in two of three games this year. He should have to air it our to keep up with the explosive Ravens’ offense here.
Baltimore’s defense, historically a strength, has shown significant weaknesses this season, ranking last in passing yards allowed (315 per game), pass attempts faced (nearly 40 per game), and ranking 30th in dropback Expected Points Added (.189). This leaky secondary provides Wilson with an opportunity to exploit a favorable matchup in this high-stakes divisional clash.
PrizePicks to Consider: Lamar Jackson MORE than 240.5 Pass Yards / Russell Wilson MORE than 229.5 Pass Yards
Chiefs vs. Bills — 4:25 p.m. ET
One of the most anticipated games of the season features a rematch between the 9-1 Kansas City Chiefs and the 8-2 Buffalo Bills. While the Chiefs have had the upper hand in recent matchups, Josh Allen is delivering an MVP-caliber season.
Allen ranks in the top 10 in both passing yards and touchdowns. In matchups against Kansas City since 2021, Allen has consistently risen to the occasion. Averaging nearly 280 passing yards per game in these matchups, he has surpassed his PrizePicks projection of 234.5 passing yards in four of the last five meetings between these two teams.
Kansas City’s defense has been stout against the run, ranking in the top five for rushing yards allowed per game. However, their pass defense remains a weak point, ranking outside the top 10 in passing yards allowed.
On the other side, Chiefs QB Patrick Mahomes mirrors Allen’s success in these matchups, regularly outperforming his projection of 243.5 passing yards in four of the last five games against Buffalo.
The Bills’ defense is slightly weaker overall, particularly against the pass, where they rank outside the top 20, allowing nearly 230 passing yards per game. Buffalo’s linebacking corps has also struggled in coverage, with Terrel Bernard and Tyrel Dodson ranking 54th and 56th, respectively, out of 72 qualified linebackers.
This sets up a favorable matchup for TE Travis Kelce, who ranks in the top five among tight ends in all major receiving categories and remains Mahomes’ most reliable target.
PrizePicks to Consider: Josh Allen MORE than 234.5 Pass Yards / Patrick Mahomes MORE than 243.5 Pass Yards / Travis Kelce MORE than 67.5 Receiving Yards
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Best OL/DL Matchups to Target: Week 11
Rams DL vs. Patriots OL
The New England Patriots boast one of the league’s worst offensive lines. Left tackle Vederian Lowe ranks 57th out of 76 tackles, allowing 18 pressures this season. His issues will be magnified against Rams defensive rookie sensation Jared Verse, who has already racked up 44 quarterback pressures this year.
The Patriots' interior offensive line is arguably in worse shape. Center Ben Brown is ranked dead last (38th out of 38 centers) and has allowed a league-high three sacks at the position. Meanwhile, left guard Michael Jordan ranks 72nd out of 77 guards. The Rams’ interior defensive lineman Kobe Turner, ranked 22nd out of 120 in his position, is expected to dominate this matchup.
PrizePicks to Consider: Drake Maye LESS than 205.5 passing yards
Broncos OL vs. Falcons DL
Atlanta’s offseason acquisition of Matthew Judon was expected to bolster their pass rush but has instead been a disappointment. Judon ranks 108th out of 112 qualified defensive ends, with just 14 pressures so far this season. On the interior, veteran Grady Jarrett has also struggled, registering only 18 pressures and three sacks.
Conversely, the Denver Broncos offensive line is one of the best in the league. Left tackle Garett Bolles ranks 14th out of 76 tackles and has allowed just one sack in over 600 snaps. Right tackle Mike McGlinchey has also surrendered just one sack in over 400 snaps. The standout of the Broncos’ unit is right guard Quinn Meinerz, who ranks 15th out of 77 guards and has allowed only one sack this season.
PrizePicks to Consider: Bo Nix MORE than 199.5 Pass Yards / Cortland Sutton MORE than 55.5 Receiving Yards
Best WR/CB Matchups to Target: Week 11
Jets WR Garrett Wilson vs. Colts CB Jaylon Jones
Jets WR Garrett Wilson continues to impress, ranking in the top five across key receiver metrics. He currently ranks fourth in receiving yards, seventh in receiving touchdowns, and second in total receptions.
This week, he faces Colts CB Jaylen Jones, a seventh-round pick out of Texas A&M who has struggled in coverage.
Jones is ranked 68th out of 108 cornerbacks, allowing a passer rating near 100 and over 14 yards per reception. Opponents have already completed 34 passes against him, placing him in the league’s bottom 20 for receptions allowed.
PrizePicks to Consider: Garrett Wilson MORE than 70.5 Receiving Yards
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Lions WR Jameson Williams vs. Jaguars CB Ronald Darby
The Jaguars’ secondary ranks among the worst in the NFL, with veteran CB Ronald Darby being a major liability. Darby is ranked 76th out of 108 cornerbacks, allowing a passer rating over 125 and nearly 14 yards per reception.
He has been heavily targeted, with 52 passes thrown his way and 38 receptions allowed, placing him in the bottom 10 for receptions conceded.
On the other hand, Detroit Lions wide receiver Jameson Williams has emerged as a significant threat following his recovery from an ACL tear.
The first-round pick is averaging nearly 21 yards per reception and boasts a passer rating of 106 when targeted, firmly establishing himself as the second option behind WR Amon-Ra St. Brown.
PrizePicks to Consider: Jameson Williams MORE than 44.5 Receiving Yards
Best TD Scorer Picks for Week 11
WR Deebo Samuel vs. Seahawks
Seattle Seahawks cornerback Tre Brown, a fourth-round pick, has faced major challenges this season. He's allowed 11 receptions, resulting in a passer rating of nearly 140 and over 15 yards per reception when targeted, placing him 98th out of 108 qualified cornerbacks in coverage grade on PFF.
This week, Brown is set to face 49ers WR Deebo Samuel. Despite battling injuries this season, Samuel remains a dynamic playmaker. When targeted, he boasts a passer rating of nearly 110 and averages over 16 yards per reception. This matchup could be challenging for Brown, given Samuel's explosive capabilities.
PrizePicks to Consider: Deebo Samuel 0.5 Rush+Rec TDs (Demon)
Dolphins WR Tyreek Hill vs. Raiders
With QB Tua Tagovailoa back under center, WR Tyreek Hill has solidified his position as a top-five WR in the NFL. Despite the Dolphins’ quarterback carousel earlier in the year, Hill has recorded 37 receptions, averaging over 12 yards per catch.
Facing him this week is Las Vegas Raiders cornerback Jack Jones. The fourth-round pick out of Arizona State has struggled in coverage, ranking 56th out of 108 qualified cornerbacks. Jones has allowed a passer rating over 115 when targeted and is surrendering more than 12 yards per reception. To date, opposing receivers have hauled in 25 of the 36 targets against him.
Regardless of who he’s facing, Hill is a cheat-code that is always a threat to get in the end-zone. The Raiders don’t have a secondary that can keep Hill in check, so expect Tua to look his way often here.
PrizePicks to Consider: Tyreek Hill 0.5 Rush+Rec TDs (Demon)
Lock in for Week 11 NFL DFS on PrizePicks
NFL Week 11 is finally upon us. Use this PrizePicks Cheat Sheet to gain the edge you need to build your winning lineup — it’s the easiest way to play NFL DFS all season long!
Head over to the PrizePicks NFL board, choose at least two player projections like yards or TDs, and lock in your Lineup. Stay in the green and you will get a real money payout when it’s all said and done.
Use the Playbook for more PrizePicks picks and predictions for NFL DFS and fantasy football all season long.
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