Is Mike Evans Playing This Week vs. Cowboys? Latest 49ers Injury Update

November 13, 2026

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NFL
AP Photo/Kelley L. Cox
San Francisco 49ers wide receiver Mike Evans (5) reacts after a getting up from a play before walking off the field during the first half of an NFL football game against the Washington Commanders in Santa Clara, Calif., Monday, Oct. 19, 2026.

San Francisco 49ers WR Mike Evans is continuing to make progress towards getting back on the field after sitting out the last two games with Achilles tendonitis. Evans is not expected to play again this week vs. the Cowboys at 4:25 p.m. ET, but is "real close" to returning.

The NFC-leading 49ers have taken a cautious approach with the six-time Pro Bowler. Evans hasn’t practiced since exiting the 49ers’ victory vs. the Washington Commanders in Week 6. 

The 49ers are coming off a 38-17 victory vs. the visiting Las Vegas Raiders despite the absence of Evans. San Francisco’s lone loss came in Evans’ first missed game, a 29-20 defeat at the Atlanta Falcons on Oct. 25. 

Below, we’ll get into the latest Mike Evans injury update, his latest practice status, the 49ers WRs' fantasy football impact, and some 49ers vs. Cowboys picks for PrizePicks. 

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Mike Evans Injury Update: Is Mike Evans Playing in Week 10 vs. Cowboys?

Evans (Achilles tendonitis) left during the second quarter of the 49ers’ Week 6 win against the Commanders. He hasn’t practiced since then and is currently listed as questionable to play in WEek 10. According to Brooke Evans of the 49ers’ official site, Mike Evans isn’t expected to play vs. the Cowboys. 

Regardless of whether he plays vs. the Cowboys or not, 49ers head coach Kyle Shanahan believes Evans is definitely trending in the right direction. 

Shanahan confirmed that Evans has reached the point in his recovery that he’d be out there if it was a playoff game. 

"Mike’s such a dog and wants to get out there all the time, and I think it’d be hard to keep him out if this was the last game or anything like that," Shanahan said via NBC Sports. "But what we’re trying not to do is have him come back and then be out right away. We’re trying to build him up the right way, so hopefully, it can last a little bit. And I think it is getting real close." 

Below, we’ll dive into what Evans' injury could mean for fantasy football and 49ers picks for PrizePicks in Week 10 if Evans misses a third consecutive game. 


49ers WRs Fantasy Football Outlook vs. Cowboys With Mike Evans Out

Heading into Sunday’s matchup against the Cowboys, Evans is currently questionable, but looking unlikely to play.

The two-time Second-team All-Pro joined the 49ers this season on a three-year contract worth up to $42.4 million after being with the Tampa Bay Buccaneers from 2014-2025. Evans has 27 receptions for 420 yards and 3 touchdowns this season. 

49ers QB Brock Purdy could still find success through the air against a Cowboys’ defense that’s 28th in dropback expected points added (EPA) per play, at 0.187, and 27th in pass TDs allowed (16).

Purdy bounced back from a 2-INT performance in the loss to the Falcons with a solid showing in the win vs. the Raiders, averaging 9.3 yards per completion, tossing 2 TDs, and rushing for another. Purdy is projected for 256.5 pass yards on PrizePicks this week — so who will lead the WR room with Evans out?

Purdy will have two additional targets at his disposal compared to last week, when second-year WR Jordan Watkins led the team with 86 yards, adding his first TD of the season.

With Deebo Samuel expected to play for the first time since Week 5, and newly-acquired Keenan Allen also expected to play, the 49ers have plenty of options, with Demarcus Robinson to boot.

In the two games with Evans sidelined, TE George Kittle led the team with 17 targets (8.5 per game), totaling 12 catches for 146 yards.

Kittle is projected for 61.5 receiving yards vs. the Cowboys — which he's surpassed in three of his last five games. He has 4+ catches in seven straight games, and sets up to be the top target again as Allen and Samuel get up to speed.

Allen is coming off a 4-26 game vs. the Cowboys last week with the Colts, and he's projected for 27.5 yards this week, though his role is relatively uncertain, especially with Samuel (projected 36.5 yards) back in the fold.

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Evans (Achilles tendonitis) appears to be trending towards being out for a third consecutive game. Shanahan does like the progress the veteran is making though, so a return might not take much longer. If Evans doesn’t suit up vs. the Cowboys, look for Deebo Samuel in his return from injury and newly-acquired Keenan Allen to soak up targets.

Don’t wait until the 4:25 p.m. kickoff on Sunday — make your 49ers vs. Cowboys picks on PrizePicks now and earn real money if you’re right.

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