The San Antonio Spurs vs. Minnesota Timberwolves Game 6 is set to tip off at 9:30 p.m. ET on Friday, May 15, with the Spurs entering as 5.5-point favorites on the spread, via PrizePicks.
The Spurs secured a convincing win in Game 5 with C Victor Wembanyama back in the lineup. With a 3-2 advantage in the Western Conference semifinals, can San Antonio top Minnesota and advance to the Western Conference Finals?
Below, we'll break down our Spurs vs. Timberwolves prediction and picks for Friday's NBA Playoff Game 6, including the spread, over/under, and key player picks for PrizePicks.
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Spurs vs. Timberwolves Prediction, Spread, Over/Under for Game 6 – Friday, May 15
In Game 4, Spurs C Victor Wembanyama was awarded a flagrant two foul for elbowing Timberwolves PF Naz Reid and was ejected from the contest. With Wembanyama receiving an early exit, Minnesota was able to take advantage and come away with a 114-109 victory.
With Wembanyama avoiding a suspension, his presence was certainly felt in a dominant 126-97 Spurs win in Game 5. Wembanyama scored a game-high 27 points on 9-of-16 shooting and grabbed 17 rebounds to pace the offensive effort for San Antonio.
The Spurs held the Timberwolves to just 38.6% shooting from the field. It also didn’t hurt that San Antonio limited Timberwolves SG Anthony Edwards to 20 points and restricted his field goal attempts throughout the night.
With the Spurs on the verge of advancing to the conference finals, the team could rely on Wembanyama to rise to the occasion on both ends of the floor yet again.
Spurs vs. Timberwolves Spread, Over/Under for Game 6 – Friday, May 15
The Spurs enter Friday’s game as 5.5-point road favorites against the Timberwolves, returning a 1.44x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Spurs vs. Timberwolves Game 6 on PrizePicks.
- Spread: San Antonio Spurs -5.5 (1.81x payout)
- Over/Under: 218.5 (1.81x payout on Over)
- Game Winner Payout: Spurs 1.44x | Timberwolves 2.63x
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Team Picks data is live at the time of writing and is subject to change.
San Antonio Spurs vs. Minnesota Timberwolves Timeline
Here is the full Spurs vs. Timberwolves timeline, including the playoff series game-by-game and recent matchup history.
All-Time: Spurs, 105-50
Regular Season: Timberwolves, 2-1
Series: Spurs, 3-2
Spurs vs. Timberwolves Timeline, Schedule for 2026 NBA Playoffs
- Game 1: Timberwolves 104, Spurs 102
- Game 2: Spurs 133, Timberwolves 95
- Game 3: Spurs 115, Timberwolves 108
- Game 4: Timberwolves 114, Spurs 109
- Game 5: Spurs 126, Timberwolves 97
- Game 6: Friday, May 15, 9:30 p.m. ET in Minnesota
- Game 7 if necessary
Spurs vs. Timberwolves Prediction on Over/Under for Game 6 – 5/15/26
Here are the key game stats and trends behind our Spurs vs. Timberwolves prediction on the over/under for Friday, May 15.
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- The over is 4-1 in the Western Conference semifinals, including 4-0 in each of the last four contests.
- The Spurs average the third-most PPG (114.7) in the NBA Playoffs, while the Timberwolves put up 108.2 PPG (sixth).
- According to NBA Advanced Stats, the Spurs have accumulated the third-best offensive rating (115.6) among playoff teams.
- San Antonio has knocked down 37.3% of its 3-point shots this postseason, ranking fourth.
- The Spurs thrive in transition, averaging 16.4 fastbreak PPG (ninth). Meanwhile, the Timberwolves aren’t far behind, averaging 15.4 PPG (12th).
- The Timberwolves have thrived on the offensive glass this postseason, pulling down the third-most offensive rebounds per contest (12.4) among playoff teams.
- The over is 8-2 in the last 10 meetings between the Spurs and Timberwolves.
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Spurs vs. Timberwolves Picks, Player Stats for PrizePicks: 5/15/26
Here are the top Spurs vs. Timberwolves picks to target in the NBA Playoffs on PrizePicks for Friday, May 15. Today’s NBA picks for PrizePicks include C Victor Wembanyama and PF Julius Randle.
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Spurs C Victor Wembanyama vs. Timberwolves Projection: 43.5 Pts + Rebs + Asts
- Wembanyama has racked up at least 44 points, rebounds, and assists in two of his nine games this postseason. It's worth noting that he left two games in the first half, once due to a concussion and the other due to the ejection.
- The Spurs’ star center has tallied 3.8 contested rebounds per contest this season, according to NBA Advanced Stats.
- Wembanyama has averaged 13.2 rebounds per game in the Western Conference semifinals and has secured at least 15 boards in four of the five outings in the series.
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Timberwolves PF Julius Randle vs. Spurs Projection: 22.5 Pts + Rebs
- Randle has recorded at least 23 points and rebounds in five of his 11 games during the 2026 NBA Playoffs.
- The Timberwolves PF has registered at least 23 points and rebounds in just two games in the Western Conference semifinals and is shooting 36.6% from the field in the series.
- According to NBA Advanced Stats, Randle has secured 3.1 contested rebounds per game this postseason.
- Per databallr, Randle has pulled down 5.4% of his teammates’ missed shots this season, ranking in the 33rd percentile.
Add Julius Randle to your PrizePicks Lineup now.
NBA Playoffs Live Picks: Spurs vs. Timberwolves on PrizePicks for Game 6
Here are some in-game angles to target for your Spurs vs. Timberwolves live picks in tonight’s game.
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- The Timberwolves have finished games strong throughout the 2025-26 season, averaging a league-best 29.6 PPG in the fourth quarter. Minnesota has averaged 30.8 PPG in the final frame in five games this series.
- Minnesota (100.50) and San Antonio (99.50) are the top two teams in terms of pace of play during the postseason, per NBA Advanced Stats.
- The Spurs lead the NBA Playoffs in third-quarter net rating (+28.9). Meanwhile, the Timberwolves rank 11th with a -20.4 mark.
- San Antonio G Dylan Harper hasn’t been nearly as efficient on the road this season. Harper is shooting just 30.7% from deep in away games compared to 39.0% at home.
Make Spurs vs. Timberwolves Game 6 Picks on PrizePicks
The Spurs and Timberwolves have put together some electric offensive performances throughout the Western Conference semifinals. Could another such showing be on tap in Game 6 with the Spurs on the verge of advancing?
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