Diamondbacks vs. Dodgers Prediction, MLB Picks for Friday, July 10

UPDATE: Per the Dodgers, Shohei Ohtani was a late scratch from Friday's pitching matchup due to knee irritation. He'll serve as designated hitter through the weekend but won't travel for All-Star festivities.

The rest of the original story resumes below.

The Arizona Diamondbacks and Los Angeles Dodgers are set to begin a three-game series on Friday, July 10, at 10:10 p.m. ET. Entering Friday’s National League West clash, the Dodgers are a heavy favorite and return a 1.35x payout to win on PrizePicks Team Picks.

On the season, Los Angeles has a 5-2 record against Arizona, winning both series thus far. The Diamondbacks are coming off a tied stint vs. the San Diego Padres, while the Dodgers defeated the Colorado Rockies in a three-game set.

Below, we'll break down our Diamondbacks vs. Dodgers prediction and picks for Friday’s MLB contest, including the run line, over/under, and key player picks for PrizePicks.

Make your Diamondbacks vs. Dodgers prediction and picks on PrizePicks now!

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Diamondbacks vs. Dodgers Prediction, Winner Payout, Over/Under – Friday, July 10

To begin the series, it will be Diamondbacks SP Eduardo Rodriguez (4.50 xFIP across 108.0 IP) and Dodgers SP Shohei Ohtani (3.26 xFIP across 85.2 IP) facing each other on the mound.

Metrics suggest that Rodriguez has gotten pretty fortunate, evidenced by him having a 2.25 ERA and 5.01 xERA, per Baseball Savant. Rodriguez is also in the 17th percentile in xBA (.266) and the 13th percentile in strikeout rate (16.9%).

Ohtani needs no introduction, as the two-way phenom has a 94th percentile xERA (2.70), 89th percentile in xBA (.201), and 83rd percentile in strikeout rate (27.9%) on the bump. Although he’s pitched 6 or more innings in 13 of his 14 starts, Ohtani has given up multiple ER in four straight outings.

Given his impressive production on the mound and at the plate, Ohtani returns the lowest payout to win the 2026 NL MVP award (1.09x) by a wide margin on PrizePicks Team Picks.

Arizona has struggled in the batter's box recently, posting the fourth-worst wRC+ (77), sixth-worst wOBA (.287), and sixth-worst ISO (.137) over the last 14 days, per FanGraphs. In the same 14-day sample, Los Angeles has the fifth-best wRC+ (118) and sixth-best wOBA (.345).

Diamondbacks vs. Dodgers Winner Payout, Over/Under – Friday, July 10

The Dodgers enter Friday’s game as a home favorite against the Diamondbacks, returning a 1.35x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Diamondbacks vs. Dodgers game on PrizePicks.

• Spread: Los Angeles Dodgers -1.5 (1.78x payout)
• Over/Under: 8.5 (1.88x payout on Over)
• Game Winner Payout: Diamondbacks 3.03x | Dodgers 1.35x

Make your Diamondbacks vs. Dodgers prediction on spread or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.

Diamondbacks vs. Dodgers Prediction on Winner – 7/10/26

Here are the key game stats and trends behind our Diamondbacks vs. Dodgers prediction on the spread for Friday, July 10.

• Although Ohtani has been a bit more shaky on the bump, he’s still posting a formidable 3.31 xFIP, 1.00 WHIP, 0.21 HR/9, and 30.9% strikeout rate when pitching at Dodger Stadium in 2026.
• Ohtani earned a win against the Diamondbacks on June 3, tossing a 6-inning shutout while permitting just 2 hits.
• Arizona also has the worst wRC+ (81), worst wOBA (.293), and second-worst ISO (.137) when facing righties.
• Rodriguez owns a 4.90 xFIP, 1.50 WHIP, 12.2% walk rate, and just a 19.3% strikeout rate in road starts this campaign.
• The Dodgers boast the sixth-best wRC+ (109), sixth-best wOBA (.332), and fourth-best ISO (.172) against lefties.

Lock in your Diamondbacks vs. Dodgers prediction on PrizePicks now.

Diamondbacks vs. Dodgers Picks, Player Stats for PrizePicks: 7/10/26

Here are the top Diamondbacks vs. Dodgers picks to target on Friday, July 10. Today’s MLB picks for PrizePicks include Freddie Freeman and Lourdes Gurriel Jr.

Dodgers 1B Freddie Freeman vs. Diamondbacks: 5.5 Hitter Fantasy Score

• Since the start of June, Freeman has the 10th-best wRC+ (167) and seventh-best wOBA (.418) among qualified hitters.
• Freeman has a solid 105 wRC+, .326 wOBA, and .333 OBP against southpaws.
• Plus, Freeman has at least 1 hit in nine of his last 10 starts, totaling 5 multi-hit performances, 2 doubles, 2 HR, 4 RBI, 1 SB, and 5 runs during that span.
• From the beginning of last season, Freeman has had at least a .404 wOBA and .311 ISO on Rodriguez’s two primary pitches (curveball, four-seam fastball) against lefties, per FantasyLabs.

Add Freddie Freeman to your PrizePicks Lineup now.

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Diamondbacks LF Lourdes Gurriel Jr. vs. Dodgers: 4.5 Hitter Fantasy Score

• Ohtani is logging a 3.06 xFIP, 0.77 WHIP, and 32.2% strikeout rate when facing right-handed sluggers.
• Along with his other elite metrics mentioned above, Ohtani is in the 92nd percentile in barrel rate (3.8%), 80th percentile in hard-hit rate (33.8%), and the 89th percentile in ground ball clip (52.1%).
• Gurriel is tallying a forgettable 64 wRC+, .267 wOBA, and .106 ISO against right-handed pitchers.
• Across his last 10 appearances, Gurriel has just 4 RBI, and 3 of those occurred in one game against the San Francisco Giants.

Add Lourdes Gurriel Jr. to your PrizePicks Lineup now.

Make Diamondbacks vs. Dodgers Picks on PrizePicks

The Dodgers have had the edge over the Diamondbacks this season, defeating their divisional foe in five of the first seven meetings. Will the reigning champs earn another victory over Arizona on Friday night?

Don’t wait until the first pitch happens — make your Diamondbacks vs. Dodgers picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

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