Best Bills vs. Vikings Anytime TD Scorer Predictions for Monday Night Football

November 9, 2026

•
NFL
Photo by Adam Bettcher/Getty Images
Minnesota Vikings WR Justin Jefferson during an NFL game vs. the San Francisco 49ers.

The NFL Week 9 slate featured some barn-burners, and one last prime-time clash in Week 9 could see more of the same. At 8:15 p.m. ET, it’s a battle of six-win teams when the Buffalo Bills and Minnesota Vikings clash on ESPN.

With Buffalo boasting one of football’s best offenses, fireworks figure to ensue on the Monday Night Football stage. Although Minnesota is down to backup QB Carson Wentz, there may not be too much of a drop-off given how poorly starter Kyler Murray was playing.

The stars are out tonight at U.S. Bank Stadium — which ones will find the end zone and score?

Below, we'll highlight our best Bills vs. Vikings Anytime TD scorer predictions for Monday Night Football, including three players who stand out.

Make your Bills vs. Vikings Anytime TD scorer picks on PrizePicks now.

{{nfl_offer_banner="/style-system/ui-components-playbook"}}


Bills vs. Vikings Anytime TD Scorer Picks for Monday Night Football – November 9

After moving on from now-former head coach Sean McDermott, the Bills have ascended to new heights on the offensive side of the ball. Buffalo rolls into Week 9 having scored more points and gained more yards than any NFL team, also sitting first in EPA per play (0.175, per RBSDM).

Monday presents a classic case of the immovable force against the unstoppable object, as the Vikings are getting it all done with their defense. With coordinator Brian Flores sending relentless pressure at opposing QBs, Minnesota cedes the lowest dropback EPA/play at -0.210.

With players like QB Josh Allen and RB James Cook taking the field for the Bills and the always-dangerous WR Justin Jefferson available for the Vikings, do they make sense are potential touchdown scorers?

Anytime TDs on PrizePicks include rushing, receiving, recoveries, and returns. PrizePicks often list Anytime TDs as Demons and Goblins, meaning users can only select "More." For standard projections, users can select “More” or “Less.”

Demons are tougher to win but are the only way to get higher payouts. Meanwhile, Goblins are lower than a standard projection, but they are easier to win, so there’s a lower payout.

Winner Spread Over/Under
BUF Bills 1.51x -3.5 | 2x o44.5 | 1.81x
MIN Vikings 2.38x +3.5 | 1.75x u44.5 | 1.92x

Bills QB Josh Allen vs. Vikings: 0.5 Anytime TDs

  • No QB has accumulated more total rush EPA than Allen at 18.95. The next-closest signal-caller is Miami Dolphins QB Malik Willis (16.87). 
  • Allen is currently pacing for 655 rushing yards and a whopping 22 rushing TDs in addition to his elite passing volume.
  • Allen has attempted 5+ rushes in each game this season, going into the double digits on two occasions.
  • With the Vikings blitzing far and away more than any other NFL team at 72.5%, Allen could be even more incentivized to scramble.
  • According to tushpush.fyi, Allen is 12-for-12 on the “Tush Push” this year and has rushed for 6 TDs on the play in 2026.
Add Josh Allen + Bills to win to your PrizePicks lineup now.

Bills RB James Cook III vs. Vikings: 0.5 Anytime TDs

  • Over his last three games, Cook is averaging 22.7 rushing attempts and 95.3 yards while scoring 4 TDs. He also has 86 receiving yards in that stretch.
  • Cook is producing 2.87 yards after contact per rush and has forced 24 missed tackles on the year, via Pro Football Focus.
  • Per Terrin Waack, Cook has gained a first down or TD on 11 of 28 red-zone attempts this year.
  • Minnesota’s defense rolled into Week 9 allowing the sixth-most runs of at least 10 yards (24), also being 17th in rushing yards per game ceded (116.7).
  • The Vikings own the eighth-highest missed tackle rate at 12.6%.
Add James Cook + Bills to cover the spread to your PrizePicks lineup now.

{{nfl_offer_banner="/style-system/ui-components-playbook"}}


Vikings WR Justin Jefferson vs. Bills: 0.5 Anytime TDs (Demon)

  • Jefferson has scored a TD in two of his last three games, also being targeted at least 7 times in the passing game in each of those contests.
  • Despite some low overall season volume relative to his standards, Jefferson still owns football’s 12th-highest target share (27.03%) for the WR position, per SumerSports.
  • In seven games with Wentz since last year, via Fantasy Points Data, Jefferson’s averaged 9.3 targets (WR10), 89.1 yards (WR5) and 17.3 fantasy points (WR10) per game.
  • Jefferson has recorded 7 red-zone targets this year, hauling in 5 passes and scoring 3 TDs in the process.
  • Buffalo ranks 25th in dropback EPA/play (0.174) ceded, also giving up th 28th-ranked success rate (49.7%).
Add Justin Jefferson + Vikings to win to your PrizePicks lineup now.

Make Bills vs. Vikings Picks on PrizePicks

In this tilt of 6-1 clubs, only one will earn its seventh win of the 2026-27 campaign. When some of the AFC and NFC’s best take the field, could the collective of Allen, Cook, and Jefferson sniff pay dirt on MNF?

Don’t wait until kickoff — make your Bills vs. Vikings picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats (including Anytime TDs), and cash in if you’re right. With Team Picks, you can make predictions on NFL game winners, spreads, and over/unders, now available in 36 states.

Stay locked in on Playbook for daily NFL predictions, picks, and news all the way through to Super Bowl LXI.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state.Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results.Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

Jordan Foote is a seasoned sports writer with years of experience covering the NFL, NBA and MLB for multiple outlets. He is a Baker University alumnus, earning his degree in Mass Media with an emphasis in sports journalism. Foote was born and raised in Kansas City, where he still resides to this day.