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NFL Week 2 kicks off on Thursday night, with the Detroit Lions and Buffalo Bills' high-powered offenses facing off. Along with monitoring injury news throughout the week, we can now factor in Week 1 usage and roles in this week's start/sit fantasy football decisions.
If you tend to stress over lineup decisions or wait until the last minute, look no further than our Week 2 fantasy football rankings.
Below, we’ll break down the Week 2 fantasy football rankings for each position, including quarterbacks, running backs, wide receivers, tight ends, and defenses.
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All fantasy football rankings below use PrizePicks NFL fantasy scoring, which includes one point per reception (PPR). Players who historically catch more passes should get a slight discount if you are in non-PPR leagues.
Week 2 QB Rankings for Fantasy Football
Here are our Week 2 quarterback rankings for the 2026 fantasy football season.
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Week 2 RB Rankings for Fantasy Football
Here are our Week 2 running back rankings for the 2026 fantasy football season.
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Week 2 WR Rankings for Fantasy Football
Here are our Week 2 wide receiver rankings for the 2026 fantasy football season.
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Week 2 TE Rankings for Fantasy Football
Here are our Week 2 tight end rankings for the 2026 NFL season.
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Week 2 Defense/Special Teams Rankings
Here are our Week 2 defense and special teams rankings for the 2026 NFL season.
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Following a high-scoring Week 1, TreVeyon Henderson, Zay Flowers, Ladd McConkey, and Brock Bowers are notable players to keep injury tabs on when it comes to injury updates ahead of Week 2.
If all of them are active, Henderson would be in the RB30 range, Flowers would be a top-10 WR, McConkey would be a top-20 WR, and Bowers would be a top-5 TE in my rankings, depending on if he's fully available.
With Week 2 of the 2026 NFL season set to kick off, which players are you rolling with in your fantasy football lineups?
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