Top NFL Picks, Predictions for Saturday Games in NFL Week 16

Eagles RB Saquon Barkley runs in for a touchdown in an NFL game vs. the Chargers. Barkley to score a TD is a top pick for NFL Saturday games.
AP Photo/Caroline Brehman

Week 16 brings us two Saturday games, including a key NFC North showdown on Saturday Night Football between the Packers vs. Bears in Chicago, a key game in the divisional race.

In the Eagles vs. Commanders Saturday game at 5 p.m. ET, the Eagles can clinch the NFC East, as Saquon Barkley will look to continue his dominance over his career division rival.

Below, we’ll break down our top NFL picks and predictions for the Saturday games in this special doubleheader on FOX, including the top player picks and PrizePicks Team Picks – where you can cash in on your Saturday NFL picks if you’re right, including teams to win.

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Philadelphia Eagles vs. Washington Commanders Prediction, Picks for Saturday

Date: Saturday, December 20

Time: 5 p.m. ET

Where to Watch: FOX

Eagles vs. Commanders Prediction & Picks for PrizePicks

Eagles vs. Commanders Over/Under Prediction

Eagles vs. Commanders Prediction on Over/Under

Eagles vs. Commanders over/under, spread, and game winner payouts are via PrizePicks Team Picks — pick on NFL games to earn real money if you’re right. All projections are live as of writing and are subject to change.

Game Winner Payout: Eagles 1.26x ($100 to payout $126) | Commanders 3.57x ($100 to payout $357)

Spread: Eagles -7.5 (1.96x payout)

Over/Under: 42.5 (1.72x payout on Over)

  • Both the Eagles (28th) and Commanders (29th) are ranked bottom five in passing play percentage and in the bottom half in pass-rate over expectation (-3.2%)
  • The Eagles are 6-0 to the under since their bye week, with an average of 33 total points per game.
  • When playing with the lead (838 snaps), the Eagles' pass rate drops to a miniscule 40% — notable as the Eagles are 6.5-point favorites here.
  • Both teams are missing one key offensive lineman, which could create additional pressure for both QBs. 
  • The Commanders ruled out PFF’s seventh-ranked OT Laremy Tunsil, while the Eagles will be without PFF’s 19th-ranked OT Lane Johnson.
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Eagles vs. Commanders Pick: Eagles RB Saquon Barkley – 0.5 Rush+Rec TD

  • After four scoreless weeks, Barkley has scored a rush TD in two straight weeks.
  • The Commanders rank 26th in EPA surrendered per rush.
  • Barkley has carried the ball 20 or more times in four of the last six games.
  • The Commanders have given up 9 TDs to opposing RBs in the last five games, and 1.15 combined TDs per game to the position.
  • In two games vs. the Commanders as a member of the Eagles, Barkley has averaged 148 yards and 2 rush TDs per game.

Green Bay Packers vs. Chicago Bears Prediction, Picks for Saturday Night

Date: Saturday, December 20

Time: 8:20 p.m. ET

Where to Watch: FOX

Bears vs. Packers Prediction & Picks for PrizePicks


Packers vs. Bears Prediction on Spread

Packers vs. Bears over/under, spread, and game winner payouts for Saturday Night Football are via PrizePicks Team Picks — pick on NFL games to earn real money if you’re right. All projections are live as of writing and are subject to change.

Game Winner Payout: Packers 1.92x ($100 to payout $192) | Bears 1.78x ($100 to payout $178)

Spread: Bears -2.5 (2.04x payout)

Over/Under: 43.5 (1.72x payout on Over)


Packers vs. Bears Promo: Caleb Williams – 182.5 Pass Yards

For the first day of PrizePicks 7-day Picksmas promos, Bears QB Caleb Williams’ pass yards are discounted from 204.5 yards to 182.5 yards. Claim the discounted pick by clicking here, or going to the NFL board.

In his last game against the Packers, on Dec. 7, Love threw for 186 yards on the road in Green Bay. In six home games this year, Love is averaging 230.2 pass yards per game.

On the other side of this game, Packers QB Jordan Love has big upside vs. a Bears pass defense that has been dominated by deep passes this year (31st in deep completions). Love ranks third in the NFL in completions 20+ yards downfield, per PFF. 

That could force Williams and the Bears' offense to air it out a bit more to keep up in what's expected to be a close game.

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Packers RB Josh Jacobs Pick vs. Bears – 61.5 Rush Yards

  • Josh Jacobs is listed as questionable vs. the Bears, but he is expected to play. Jacobs was also questionable last week. 
  • He would have practiced on Tuesday if the Packers held a practice, per Packers head coach Matt LaFleur.
  • Jacobs rushed 12 times for 73 yards vs. the Broncos in Week 15 despite the same injury after re-aggravating it in Week 14.
  • The Broncos have the 12th-ranked defense in expected points added (EPA) per rush. The Bears rank 22nd in the same stat.
  • Jacobs rushed for 86 yards vs. the Bears in Week 14 on 20 carries.
  • The Bears surrender 4.79 yards per carry to RBs, which ranks 26th, per CBS Sports.

Make Saturday NFL Picks on PrizePicks

Whether you’re riding with the Packers or Commanders to win, the Caleb Williams pass yards promo, or Jalen Hurts — the best place to make your Saturday NFL picks is on PrizePicks.

Pick NFL winners, spreads, and over/unders to earn real money if you’re right on PrizePicks Team Picks (available in 22 states), or pick More or Less on player stat projections to win up to 2000x your money on Player Picks (in 45 states).


Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

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about the author

Christian Hardy is a Content Specialist and Digital Copywriter at PrizePicks and is a graduate of the University of Kansas School of Journalism (2018). He has been writing about fantasy sports since 2011, when waiver wire debates happened on forums. Born and raised in Kansas, he now lives in Tampa, Florida, with an unwavering loyalty for the Dallas Cowboys and Tampa Bay Rays, who have brought him the pure joy of a ring zero times in his life.

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