Top MLB Home Run Picks Today on PrizePicks – Wednesday, September 2

It’s yet another busy day in MLB here in early September, leaving a multitude of opportunities for all 30 teams to impact the standings in some way, shape, or form. With all the stars taking the field from the early afternoon and deep into the night, where will power production come from?

Here at PrizePicks, we have plenty of home run projections on the board to add to your MLB picks today. Many hitters have already been singled out by users as popular home run picks for the day’s action.

Let’s dive into some of the most-picked MLB home run projections for Wednesday, September 2, including what makes each player a potential target for home run predictions. 

Make your MLB home run picks for Wednesday, September 2 on PrizePicks now.  

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Top MLB Home Run Picks Today – Wednesday, September 2

Nothing gets a crowd or a dugout going quite like a home run, and this MLB season has brought plenty of them. It’s much easier said than done, however, which makes predicting one a bit challenging.

Repeatable trends from hitters such as bat speed, launch angle, barrel rate, and more can give viewers a good idea of who has the highest “floor” as a power hitter. Some things can’t be controlled, including ballpark dimensions, weather, and the opposing pitcher. Factoring in all of that for Wednesday, there’s an intriguing list of players who might be able to go yard. 

Which players could be in good positions to swat a homer on Wednesday? Daily home run projections are listed as Demons on PrizePicks, coming with higher payouts as a result. Home runs can only be selected as “More” than 0.5. 

Let’s take a look at the most popular home run picks today on PrizePicks. Picks are listed at the time of writing.

1. Cubs CF Pete Crow-Armstrong
2. Yankees DH/1B Ben Rice
3. White Sox 3B Miguel Vargas
4. Cardinals RF Jordan Walker
5. Giants 1B Rafael Devers
6. Tigers C Dillon Dingler
7. Orioles SS Gunnar Henderson
8. Brewers 1B Jake Bauers

Three home run picks stand out as potential targets today. Let’s dive into the list, including a weather report from RotoGrinders.

Unless otherwise noted, data used in this article is from Baseball Savant or FanGraphs.

Yankees DH/1B Ben Rice

Yankees vs. Angels – 9:38 p.m. ET

Angels Starting Pitcher: Reid Detmers

MLB Weather Report: 75 degrees, clear skies, 6 mph west-southwest wind

• Rice has already hit 9 more home runs than a year ago, including raising his ISO from .244 to .268. 
• The veteran infielder has steadily improved his home-run-to-fly-ball ratio from 14.6% in 2024 to 17.1% last year and a significant jump to 24.3% this campaign.
• Per Savant, Rice slots into the 95th percentile in xSLG (.506) and the 94th percentile in barrel rate (14.6%).
• Detmers is giving up a 17.7-degree average launch angle and a 44.9% fly ball share, both his highest since 2021.
• The 27-year-old lefty hurler sits in just the 18th percentile in average exit velocity at 90.0 mph. 

Add Ben Rice to your PrizePicks lineup now.

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Orioles SS Gunnar Henderson

Orioles vs. Rockies – 3:10 p.m. ET

Rockies Starting Pitcher: Tomoyuki Sugano

MLB Weather Report: 86 degrees, clear skies, 5 mph east-southeast wind

• Henderson has been tremendous in the month of August, owning a .447 SLG, .202 ISO, and 136 wRC+.
• Gunnar is hitting more fly balls than ever, posting a 38.3% rate that clears his previous personal best of 35.9% from 2023.
• Despite having an up-and-down year, peripherals like Henderson’s 74th-percentile bat speed (74.4 mph) and 68th-percentile hard-hit rate (43.8%) are promising.
• Sugano has been one of baseball’s worst pitchers when it comes to giving up long balls, evidenced by his 1.89 HR/9 in his debut season and a 1.93 mark in 2026.
• The 36-year-old righty resides in the third percentile or worse in xERA (6.94), xBA (.314), average exit velo (91.1 mph), barrel rate (12.7%), and more. 

Add Gunnar Henderson to your PrizePicks lineup now.

Brewers 1B Jake Bauers

Brewers vs. Cubs – 7:40 p.m. ET

Cubs Starting Pitcher: David Peterson

MLB Weather Report: 85 degrees, clear skies, 9 mph southwest wind

• In his age-30 season, Bauers’ breakout is in full swing, proven by a career-high 23 home runs and a .222 ISO.
• The soon-to-be free agent actually has reverse batting splits, owning a .531 SLG against lefties compared to a .482 figure vs. right-handers. 
• Bauers swings a firm bat, owning a 76.6 mph average bat speed and a 69.1% fast-swing percentage. 
• Peterson’s sinker and four-seamer are nothing to write home about, as he gives up respective SLG of .442 and .457 on them. Bauers slugs .520 and .541 when seeing the two offerings. 
• Chicago’s 6-foot-6 Wednesday starter allows plenty of hard contact to the tune of a 41.2% hard-hit clip (27th percentile).  

Add Jake Bauers to your PrizePicks lineup now.

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There’s no shortage of home run potential in Wednesday’s MLB action, but the Rice-Henderson-Bauers trio might take the cake as players who have some favorable matchups and always seem to be threats to crush a long ball.

Don’t wait until first pitch — make your MLB home run picks on PrizePicks now and earn real money if you’re right.

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