Top MLB Home Run Picks Today on PrizePicks – Friday, May 29

On Friday, MLB has a full 15-game slate with a handful of tantalizing matchups. New York Yankees OF Aaron Judge is one of several hitters who are worth keeping an eye on throughout Friday’s schedule.

PrizePicks offers daily home run projections for all your MLB picks, and many hitters have already been targeted by users as some of the most popular home run picks throughout Friday’s action.

Below, we’ll break down the most-picked MLB home run predictions for Friday, including each player’s matchup, recent production, and what makes them a popular home run pick.

Make your MLB home run picks for Friday, May 29, on PrizePicks now.

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Top Home Run Picks Today – Friday, May 29

Slugging a home run is one of the toughest feats that a player can achieve on the diamond. As a result, it can be quite difficult to project which player could go yard on a given day.

Several factors can contribute to a home run being hit each day. How hard has a player been hitting the ball recently? Has the opposing starter been serving up several fly balls? Could weather conditions be a factor? 

Home run projections are labeled as Demons on PrizePicks, which comes with a higher payout. You can only choose “More” on home run projections, which are set at 0.5.

Here’s a look at the most popular home run picks for today on PrizePicks as of writing.

1. Yankees OF Aaron Judge
2. Phillies DH Kyle Schwarber
3. Dodgers DH Shohei Ohtani
4. Athletics DH Brent Rooker
5. Astros DH Yordan Alvarez
6. White Sox 1B Munetaka Murakami
7. Cardinals OF Jordan Walker
8. Twins OF Byron Buxton
9. Braves 1B Matt Olson
10. Nationals OF James Wood

Below, we’ll break down three matchups for today, including the opposing starting pitcher with advanced stats from FanGraphs and Baseball Savant, capped by a weather report via RotoGrinders.

Yankees OF Aaron Judge

New York Yankees vs. Athletics – 9:40 p.m. ET

Athletics Starting Pitcher: Luis Severino (11 GS, 2-5, 4.03 xFIP, 38.9% hard-hit, 38.2% FB%)

MLB Weather Report: 73 degrees, clear skies, and winds 5 mph to left field

• Judge has belted 17 home runs in 2026, which is tied for third in the majors.
• The Yankees’ star has slugged 12 of his 17 home runs against right-handed pitchers this season.
• Judge has tallied a 28.3% home run-to-fly ball rate in 2026, including 17 career home runs vs. the Athletics.
• The Yankees’ outfielder has recorded a 44.8% fly ball rate in 2026, while Severino has given up a 38.2% fly ball rate (his highest since 2022).
• Judge has also registered a 22.4% barrel rate (99th percentile), a 57.5% hard-hit rate (98th), and a 94.3 mph average exit velocity (98th).
• Severino has surrendered 8 home runs while also coughing up a 1.17 HR/9 and a 12.7% HR/FB rate in 2026. He has yielded 3 home runs across his last two outings.

Add Aaron Judge to your PrizePicks Lineup now.

Cardinals OF Jordan Walker

Chicago Cubs vs. St. Louis Cardinals – 7:15 p.m. ET

Cubs Starting Pitcher: Shota Imanaga (11 GS, 4-5, 3.52 xFIP, 39.8% hard-hit, 44.8% FB%)

MLB Weather Report: 82 degrees, 24% chance of rain, and 8 mph winds toward third base

• Walker has slugged 15 home runs this season, which is tied for fifth in the majors.
• The Cardinals’ outfielder has blasted 4 home runs against left-handed pitching in 2026.
• Walker has registered a career-high 23.4% HR/FB rate this season and has belted 2 home runs over his last five games.
• The Cardinals’ standout has also tallied a 94.2 mph average exit velocity (98th percentile), a 52.0% hard-hit rate (95th), and a 15.5% barrel rate (91st) in 2026.
• Walker has recorded a career-best 43.2% fly ball rate, while Imanaga has surrendered a 44.8% fly ball rate.
• Imanaga has yielded 10 home runs in 2026, while also giving up a 1.39 HR/9 and a 12.8% HR/FB rate.

Add Jordan Walker to your PrizePicks Lineup now.

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Blue Jays 3B Kazuma Okamoto

Toronto Blue Jays vs. Baltimore Orioles – 7:05 p.m. ET

Orioles Starting Pitcher: Trevor Rogers (9 GS, 2-6, 4.69 xFIP, 37.1% hard-hit, 42.7% FB%)

MLB Weather Report: 77 degrees, clear skies, and winds 5 mph to right field

• Okamoto has slugged 11 home runs throughout the 2026 season, which leads the Blue Jays.
• The Blue Jays’ third baseman may have only 2 home runs against left-handers, but he's hitting .261 against lefties, compared to just .201 vs. right-handers.
• Okamoto has registered a 19.6% HR/FB rate and recently blasted a home run vs. the Miami Marlins on Wednesday.
• The Blue Jays’ power hitter has tallied a 43.4% fly ball rate this season, while Rogers has given up a career-high 42.7% fly ball rate.
• Okamoto has also racked up a 51.9% hard-hit rate (94th percentile), a 92.8 mph average exit velocity (93rd), and a 14.7% barrel rate (87th).
• Rogers has yielded 6 home runs in 2026, while also surrendering a 1.27 HR/9 and a 9.8% HR/FB rate.

Add Kazuma Okamoto to your PrizePicks Lineup now.

Make MLB Home Run Picks on PrizePicks

Aaron Judge, Jordan Walker, and Kazuma Okamoto could all benefit from their respective pitching matchups on Friday evening. Who could end up going yard?

Don’t wait until the first pitch — make your home run picks on PrizePicks now and earn real money if you’re right.

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