Top MLB Home Run Picks Today on PrizePicks – Friday, June 12

Heading into the weekend, the MLB slate features all 30 teams taking the field from the evening through the end of the night. That volume brings ample opportunities for home runs, and there’s no shortage of impressive talents who might be capable of sending a ball over the fence.

Here at PrizePicks, we have plenty of home run projections on the board to add to your MLB picks today. Many hitters have already been singled out by users as popular home run picks for the day’s action.

Let’s dive into some of the most-picked MLB home run projections for Friday, June 12, including what makes each player a potential target for home run predictions. 

Make your MLB home run picks for Friday, June 12 on PrizePicks now.  

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Top Home Run Picks Today – Friday, June 12

As the weather heats up and summer arrives, the ball is flying through the air even more. The league could see an uptick in daily home run production, which opens the door for home run picks each time out.

Don’t get it twisted, though, as hitting a home run is still quite difficult. It takes more than a quick swing or a strong player to belt a homer. Ballpark dimensions, pitcher specifics, launch angle, contact quality and more all factor into an extra-base hit turning into an exciting home run. 

Daily home run projections are listed as Demons on PrizePicks, coming with higher payouts as a result. With that said, home runs can only be selected as “More” than 0.5. 

Let’s take a look at the most popular home run picks today on PrizePicks. Picks are listed at time of writing.

1. Astros DH Yordan Alvarez
2. Phillies 1B Bryce Harper
3. Nationals SS CJ Abrams
4. Athletics C Shea Langeliers
5. Nationals OF James Wood
6. Mariners CF Julio Rodriguez
7. Yankees 1B Ben Rice
8. Orioles SS Gunnar Henderson
9. Astros 1B Christian Walker

Three home run picks stand out as potential targets today. Let’s dive into the list, including a weather report from RotoGrinders.

Unless otherwise noted, data used in this article is from Baseball Savant or FanGraphs.

Astros DH Yordan Alvarez

Astros vs. Royals – 8:10 p.m. ET

Royals Starting Pitcher: Luinder Avila

MLB Weather Report: 82 degrees, clear skies, 5 mph south-southeast wind

• Alvarez’s power production continues to shine through, as his .320 ISO is his highest mark since a two-game sample in 2020 and an 87-game stretch from his debut in 2019.
• The veteran slugger has upped his average launch angle to a career-high 19.1 degrees, and his 18.4% barrel rate is his best since 2022. 
• Yordan’s ground ball rate is down to 27.0%, and as a result, his 48.0% fly ball percentage has never been higher.
• The star DH ranks in the 100th percentile in xSLG (.729) and is in the 99th percentile in launch angle sweet-spot share (45.9%). 
• Avila is in just the 42nd percentile with an 8.1% barrel rate allowed. 

Add Yordan Alvarez to your PrizePicks Lineup now.

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Athletics C Shea Langeliers

Rockies vs. Athletics – 10:05 p.m. ET

Rockies Starting Pitcher: Undecided

MLB Weather Report: 95 degrees, clear skies, 10 mph southwest wind

• Langeliers’ career campaign rolls on, seeing him post a 140 wRC+ and a .535 SLG that’s nearly identical to last year’s mark of .536. 
• The 28-year-old catcher, like Alvarez, has a career-high launch angle at 20.8 degrees and is also holding a personal best 14.8% barrel rate.
• Langeliers has leveled up his fast swing rate from 39.7% in 2025 to a staggering 53.0% in 2026. 
• The Athletics’ star backstop is in the 85th percentile in average exit velocity (91.6 mph).
• Don’t throw a fastball to Langeliers. He’s hitting .293 against the pitch in 2026 while slugging .618 with a .664 xSLG. 

Add Shea Langeliers to your PrizePicks Lineup now.

Orioles SS Gunnar Henderson

Padres vs. Orioles – 7:05 p.m. ET

Padres Starting Pitcher: Griffin Canning

MLB Weather Report: 88 degrees, partly cloudy skies, 6 mph west wind

• In addition to hitting the ball in the air more now than ever (37.9%), Henderson has upped his pull rate to 46.0%. 
• Could Henderson be due for some positive regression in the future? His .253 BABIP is far below his career average of .311.
• Henderson’s 74.5 mph bat speed slots into the 77th percentile. 
• In 8 at-bats for his career against Canning, Henderson is hitting .500 with an average exit velocity of 99.9 mph. 
• Canning is surrendering 1.65 HR/9, his most since 2021, while also residing in the second percentile in both hard-hit rate (50.6%) and average exit velo (92.2 mph). 

Add Gunnar Henderson to your PrizePicks Lineup now.

Make MLB Home Run Picks on PrizePicks

The stars are out on Friday night, and there are some conducive home run environments across the slate. Which players will go yard as the weekend approaches?

Don’t wait until first pitch — make your MLB home run picks on PrizePicks now and earn real money if you’re right.

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