Detroit Tigers vs. Chicago Cubs is set for first pitch at 8:05 p.m. ET on Tuesday, July 21, with the Cubs favored and returning a 1.78x payout if they win, via PrizePicks.
After a dramatic 8-6 win in 10 innings Monday, the Tigers will try to build on it with SP Framber Valdez (5-6, 4.10 ERA) on the mound. The Cubs will counter with SP David Peterson (4-7, 6.45 ERA), who is having the worst season of his career.
Below, we’ll break down our Tigers vs. Cubs prediction and picks for Tuesday’s MLB game, including game winner, over/under, and key player picks for PrizePicks.
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Tigers vs. Cubs Prediction, Winner Payout, Over/Under – Tuesday, July 21
The Tigers are having a disappointing season with their 47-53 record. Their lineup has been the main culprit, ranking 18th in the majors with a 99 wRC+, according to FanGraphs. They do have power, sitting 12th in ISO (.165).
With that said, they struggle to get hits in big spots. Their .238 batting average with runners in scoring position is the fifth-worst mark in baseball.
The Cubs have been more potent at the plate, posting the fourth-highest wRC+(110). They are very selective, recording the highest walk rate (11.1%) that's paired with a modest 21.5% strikeout rate.
Tigers vs. Cubs Winner Payout, Over/Under – Tuesday, July 21
The Cubs enter Tuesday’s game as a home favorite against the Tigers, returning a 1.78x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Tigers vs. Cubs game on PrizePicks Team Picks — where you can make real money predictions on every MLB game!
- Spread: Chicago Cubs -1.5 (2.56x payout)
- Over/Under: 8.5 runs (1.88x payout Over)
- Game Winner Payout: Tigers 1.92x | Cubs 1.78x
Make your Tigers vs. Cubs prediction on spread or over/under on PrizePicks Team Picks — available in 35 states!
Team Picks data is live as of writing and is subject to change.
Tigers vs. Cubs Prediction on Winner – Tuesday, July 21
Here are the key game stats and trends behind our Tigers vs. Cubs prediction on the winner for Tuesday, July 21.
- Even with Monday’s loss, the Cubs are 29-21 at home. It was a rare road win for the Tigers, who are 20-30 away from Detroit.
- Although the Tigers have a losing record, they have a +33 run differential. They're the only team in baseball with a losing record and a positive run differential.
- Peterson has been awful, owning a 5.36 xERA between his time with the Mets and Cubs this year.
- Across three appearances with the Cubs, the veteran lefty has a 1.60 WHIP and gave up 13 runs over 14.1 innings.
- Valdez pitched well heading into the All-Star break, permitting 1 or no runs in five of his last nine starts. Over that span, he posted a 3.59 ERA and a 1.23 WHIP.
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Tigers vs. Cubs Picks, Player Stats for PrizePicks: 7/21/26
Here are top Tigers vs. Cubs picks to target on Tuesday, July 21. Today's MLB picks for PrizePicks include C Dillon Dingler and SS/3B Kevin McGonigle.
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Tigers C Dillon Dingler vs. Cubs: 5.5 Hitter Fantasy Score
- Dingler carried the Tigers’ lineup Monday, hitting 4-for-5 with 2 home runs, 3 RBI, and 3 runs scored.
- The power-hitting catcher has 21 home runs over 91 games this year. Last season, he only went deep 13 times in 126 games.
- One of the reasons for his increased power is that Dingler has a 10.9% barrel rate, which is up from 9.2% last season.
- Right-handed hitters have plenty of success against Peterson, providing a .361 wOBA against him. He has a staggeringly low 13.7% strikeout rate against righty sluggers.
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Tigers SS/3B Kevin McGonigle vs. Cubs: 1.5 Hits + Runs + RBI
- McGonigle went 1-for-4 with a double and 2 walks Monday. That was the ninth time over his last 11 games that he came away with at least 1 hit.
- The rookie has an excellent eye, recording a higher walk rate (14.6%) than strikeout rate (13.7%).
- McGonigle has a .160 ISO and a .371 wOBA on the road compared to a .128 ISO and .357 wOBA at home.
- Although he doesn’t have the platoon advantage in this matchup, the young infielder has a respectable 105 wRC+ vs. southpaws.
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With the struggling Peterson on the mound, the Tigers could pull off another road upset. Their lineup has added upside in this matchup, with Dingler and McGonigle being two hitters in particular that could shine.
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