Red Sox vs. Rays Prediction, MLB Picks for Wednesday, June 10

First pitch of the matchup between the Boston Red Sox (27-38) and Tampa Bay Rays (39-25) is set for 1:10 p.m. ET on Wednesday, June 10, with the Rays returning a 1.61x payout to win, via PrizePicks.

The Rays have opened up the closet and are ready to pull out the broom as they go for the sweep. Tampa Bay has dominated the season series, winning four of the five games, and tops the American League East while Boston is a cellar-dweller.

Below, we'll break down our Red Sox vs. Rays prediction and picks for Wednesday’s MLB matchup, including the run line, over/under, and key player picks for PrizePicks.

Make your Red Sox vs. Rays prediction on PrizePicks for today’s game.

{{mlb_offer_banner="/style-system/ui-components-playbook"}}

Red Sox vs. Rays Prediction, Winner Payout, Over/Under – Wednesday, June 10

The Red Sox will send rookie SP Jake Bennett (4.31 xFIP across 2 starts and 10.1 IP in 2026) to the mound. The No. 6 prospect in Boston’s farm system has not pitched for the big club since May 7, and it was against the Rays, where they knocked him around for 4 earned runs in 5.1 innings.

There's a lot of potential for the future of this southpaw. According to his Baseball Savant scouting report, he has great command of his pitches — especially his changeup, where he can get batters to chase it out of the zone.   

As the trade deadline approaches, major changes could occur in Boston, with the team potentially becoming sellers. The firing of Alex Cora after a 10-17 record didn't rejuvenate them, as interim manager Chad Tracy is just 17-21 since taking over.

The Sox are in the middle of an eight-game stretch against their American League East rivals (Orioles, Yankees, and Rays), which was a great opportunity to get back into contention. Instead, they've gone 2-5 and lost ground in the standings, now sitting 12.5 games back.

The Rays will counter with SP Drew Rasmussen (3.02 xFIP across 12 starts and 66 IP in 2026). Although he’s in his seventh year in the league, he’s been in and out of the rotation, and this is just his third year with at least 12 starts.

It's unfortunate that he didn’t get this opportunity earlier in his career, because he’s excelling in the role. He’s one of the top starters in baseball; his 0.92 WHIP is second in the league and his 3.00 ERA is eighth.

The Rays have recently fallen into a slump, losing 9 of their last 14 games. The 4.5-game lead they built while going 29-8 from April 10 to May 22 is gone, as the Yankees are tied with them for first place in the AL East. 

The pitching has struggled during this rough patch. Since May 24, they rank 25th in xERA (4.72) and 26th in home runs allowed per nine innings (1.6).

Red Sox vs. Rays Winner Payout, Over/Under – Wednesday, June 10

The Rays enter Wednesday’s game as home favorites, returning a 1.61x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Red Sox vs. Rays game on PrizePicks.

• Spread: Tampa Bay Rays -1.5 (2.27x payout)
• Over/Under: 8.5 (2.04x payout on Over)
• Game Winner Payout: Red Sox 2.17x | Rays 1.61x

Play the Red Sox vs. Rays spread or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.

Red Sox vs. Rays Prediction on Spread – 6/10/26

Here are the key game stats and trends behind our Red Sox vs. Rays prediction on the runline for Wednesday, June 10.

Lock in your Red Sox vs. Rays prediction on PrizePicks now.

Unless otherwise noted, data used in this article is from Baseball Savant or FanGraphs.

• Rasmussen is keeping opponents’ bats quiet, as his 32.0% hard-hit rate allowed ranks in the 85th percentile. The Red Sox rank 19th with a 38.9% hard-hit rate.
• The Rays are 4-1 at home this season when Rasmussen starts.
• Boston’s lack of power shows in its 8.2% home run-to-fly ball ratio, which ranks dead last in MLB. That may benefit Rasmussen, who's allowing only 1.1 HR/9 and has ceded just 1 over his last three starts.
• The Red Sox’s 19-29 record against right-handed starters is second-worst in the sport.
• Although the Red Sox pitching staff ranks a respectable 11th with a 24.6% whiff rate allowed, they have to face a Rays’ offense whose 19.9% whiff rate is the lowest in the league.

Red Sox vs. Rays Picks, Player Stats for PrizePicks: 6/10/26

Here are the top Red Sox vs. Rays picks to target on Wednesday, June 10. Today’s MLB picks for PrizePicks include Willson Contreras and Yandy Diaz.

Red Sox 1B Willson Contreras vs. Rays: 4.5 Hitter Fantasy Score

• Contreras is having his best season, as his .532 xSLG and .400 wOBA are career highs.
• The Red Sox first baseman has recently been one of the top hitters in baseball. Since May 9, he ranks fourth in OPS (1.052) and BABIP (.393).
• Rasmussen struggles by allowing a 7.2% barrel rate that ranks in the 53rd percentile. Contreras has a distinct advantage, as his 15.5% barrel rate resides in the 92nd percentile.
• Contreras has reached base safely in both plate appearances against Rasmussen with a hit and a walk.
• Rasmussen throws a cutter on 33.6% of his pitches. Contreras has been successful against that pitch this season with a .407 wOBA and 77.8% hard-hit rate.

Add Willson Contreras to your PrizePicks Lineup now.

{{mlb_offer_banner="/style-system/ui-components-playbook"}}

Rays DH Yandy Diaz vs. Red Sox: 5.5 Hitter Fantasy Score

• Diaz is having a fantastic year, as his .298 xBA is the second-best of his career and his .405 wOBA is a career high.
• He enters tonight reaching base in 23 consecutive games. Since May 12, when this streak started, he ranks third with a .471 wOBA and sixth with 1.3 WAR.
• The Rays designated hitter rarely leaves an at-bat empty-handed, as his 13.7% whiff rate ranks ninth and his 88.9% contact rate is eighth.
• Diaz has been productive in this series, going 2-for-6 with 1 home run, 2 RBI, and 2 walks.

Add Yandy Diaz to your PrizePicks Lineup now.

Make Red Sox vs. Rays Picks on PrizePicks

Rays SP Drew Rasmussen has a chance to get his sixth win of the season, which would put him more than halfway to his career-high of 11. He faces a struggling Red Sox team, which has lost four of its last five series and is trying to avoid the sweep.

Don’t wait until the first pitch — make your Red Sox vs. Rays picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

Stay locked in on Playbook for daily MLB predictions, picks, and news every day all the way through the 2026 MLB season.