Phillies vs. Dodgers Prediction, MLB Picks for Friday, May 29

Phillies vs. Dodgers is set for first pitch at 10:15 p.m. ET on Friday, May 29. The Dodgers return a 1.78x payout if they win, via PrizePicks.

The first-place Dodgers (36-20) host the surging Phillies (29-27) in the marquee battle of the weekend. L.A. starts its second series of the homestand after taking two of three from the Rockies, and Philadelphia plays its fourth of a total of six games in California on this trip.

Below, we’ll break down our Phillies vs. Dodgers prediction and picks for Friday’s MLB game, including game winner, over/under, and key player picks for PrizePicks.

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Phillies vs. Dodgers Prediction, Winner Payout, Over/Under – Friday, May 29

As expected, the Dodgers won their series with the Rockies in Shohei Ohtani’s start on Wednesday. Ohtani started the game with 6.0 no-hit innings and joined Andy Pages and Freddie Freeman with home runs in the 4-1 victory.

L.A.’s record (15-12) in May might not indicate their strength, as the team is fifth in ERA (3.03) and second in wRC+ (118) in this period of time.

The Fightin’ Phillies, meanwhile, remain red-hot. They swept the Padres in San Diego earlier this week, bringing their May record to a scorching 19-9 as they continue to dig out of what was an early-season hole.

Cristopher Sanchez tossed 7 scoreless innings on Wednesday, and Trea Turner’s round-tripper gave the team all the offense it needed.

Both teams enter off a day of rest, but it’s the home side fighting the injury bug a bit more. After losing Enrique Hernandez earlier this week, Teoscar Hernandez strained his hamstring against the Rockies and has been transferred to the IL.

Phillies vs. Dodgers Winner Payout, Over/Under – Friday, May 29

The Dodgers enter Friday’s game as a slight home favorite against the Phillies, returning a 1.78x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Phillies vs. Dodgers game on PrizePicks.

• Spread: Los Angeles Dodgers -1.5 (2.63x payout)
• Over/Under: 8.5 runs (1.96x payout Over)
• Game Winner Payout: Phillies 1.96x | Dodgers 1.78x

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Team Picks data is live as of writing and is subject to change.

Phillies vs. Dodgers Prediction on Winner – 5/29/26

Here are the key game stats and trends behind our Phillies vs. Dodgers prediction on the winner for Friday, May 29.

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• The Phillies are a perfect 6-0 in Zack Wheeler’s starts this season. Wheeler also enters on a stretch of 5 consecutive quality starts.
• Philadelphia has the second-highest team OPS (.844) against left-handed pitching in May.
• Justin Wrobleski’s skill-interactive ERA (4.87 SIERA) is considerably higher than his listed ERA (3.30). He’s surrendered 10 earned runs in four home starts this year.
• The Phillies’ 19-8 record under new manager Don Mattingly is the third-best in baseball since he was hired.
• Los Angeles has an identical 18-10 record both at home and on the road.
• Both the Phillies and Dodgers have two of MLB’s three best bullpen SIERAs during the month of May.

Phillies vs. Dodgers Picks, Player Stats for PrizePicks: 5/29/26

Here are the top Phillies vs. Dodgers picks to target on Friday, May 29. Today's MLB picks for PrizePicks include Kyle Schwarber and Justin Wrobleski.

Phillies DH Kyle Schwarber vs. Dodgers: 5.5 Hitter Fantasy Score

• Schwarber is third among all MLB players (min. 10 plate appearances) in OPS against left-handed pitching this month (1.543).
• The designated hitter has a 60.0% fly ball rate and 60.0% hard-hit rate against southpaws in this same period, resulting in 6 extra-base hits in 26 plate appearances.
• Statcast’s park factors list Dodger Stadium as the seventh-friendliest venue for runs and the most friendly park for home runs in baseball.
• L.A.’s Kyle Wrobleski’s low swinging-strike rate (7.2%) meets Schwarber’s problematic punchout rate against lefties (29.9%).

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Dodgers LHP Justin Wrobleski vs. Phillies: 4.5 Strikeouts

• Dating back to the start of 2025, the Phillies have the ninth-lowest team strikeout rate against left-handed pitching (22.3%).
• Wrobleski has posted his four highest barrel rates allowed of the season in his last four starts. This is just his second at Dodger Stadium in this stretch after allowing 7 earned runs in his last home appearance.
• The southpaw’s contact rate (82.8%) is 14th-highest in MLB. 

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Looking to play spoiler on the road, the Phillies turn to Zack Wheeler in hopes of a fourth straight win in Cali, but the Dodgers are always a tough out at home with a star-studded lineup and quality pitching staff.

Don’t wait until the first pitch — make your Phillies vs. Dodgers picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

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