Thursday Night Football Pick Against the Spread for Panthers vs. Packers Tonight

October 29, 2026

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NFL
AP Photo/Duane Burleson
Packers RB Josh Jacobs scores a touchdown during an NFC North game vs. the Lions.

The Thursday Night Football matchup in Week 8 will have the Carolina Panthers traveling to take on the Green Bay Packers at Lambeau Field on Prime Video at 8:15 p.m. ET. The Packers enter the game as 3.5-point home favorites on PrizePicks.

Carolina wants to get the bad taste out of its mouth after getting trounced 43-13 in Week 7 by the Tampa Bay Buccaneers. Although vibes aren’t extremely high coming off that loss, the Panthers are still atop the NFC South with a 3-3 record.

Meanwhile, Green Bay suffered a narrow 20-17 loss in Week 7 to the Detroit Lions. With the NFC North featuring four teams with winning records entering Week 8, the Packers oddly find themselves in last place in the division with a 4-3 record.

Below, we’ll break down our Panthers vs. Packers prediction and pick against the spread from PrizePicks for Thursday Night Football in NFL Week 8. 

Make your Panthers vs. Packers prediction on PrizePicks for TNF!

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Panthers vs. Packers Prediction, Spread, Over/Under for Thursday Night Football Week 8

The Packers enter Thursday’s game as 3.5-point home favorites against the Panthers, returning a 1.47x payout on PrizePicks if they win outright.

Here are the full payouts for the Panthers vs. Packers game on Thursday Night Football. PrizePicks data is live at the time of writing and is subject to change.

Win Spread Total
CAR Panthers 2.56x +3.5 | 1.88x o47.5 | 1.92x
GB Packers 1.47x -3.5 | 1.85x u47.5 | 1.81x
Make your Panthers vs. Packers prediction on the spread on PrizePicks.

Across the first six weeks of the season, QB Bryce Young was playing at an impressive level. Among the 27 QBs with 150 or more plays through Week 6, Young was seventh in adjusted EPA/play (0.22) and ninth in completion percentage over expected (+3.0%), per RBSDM.

However, of the 27 QBs with 25 or more plays in Week 7, Young finished 27th in both adjusted EPA/play (-0.50) and completion percentage over expected (-15.7%). Carolina’s defense also didn’t do the team any favors in the lopsided loss to Tampa Bay, especially against the run.

Excluding the kneel-downs to conclude the game, the Buccaneers gashed the Panthers’ run defense for 261 rushing yards and 3 rushing TDs on 47 attempts. RB Bucky Irving led the way for Tampa Bay with 106 yards and 2 TDs.

As for the Packers, QB Jordan Love has been leaned on plenty, with the team lacking an effective rushing attack. While Green Bay is 10th in neutral pass rate (55.5%) entering Week 8, it did get RB Josh Jacobs back vs. Detroit in Week 7.

Despite Jacobs rushing for only 36 yards on 11 carries in his season debut, the veteran back contributed 5 catches, 55 receiving yards, and a score as a pass-catcher. Jacobs’ return to the offense could add another element that’s been missing this season.

Jacobs is projected for 61.5 rush yards, 17.5 receiving yards, and a 15 fantasy score tonight, per PrizePicks.

On the defensive side of the ball, the Packers didn’t have many answers for QB Jared Goff and the Lions’ passing attack, allowing Goff to air it out for 303 yards and 2 TDs on only 32 attempts. After failing to generate consistent pressure against Goff in Week 7, Green Bay’s defense will need to collapse the pocket to make Young uncomfortable.


Panthers vs. Packers Prediction on Spread for Thursday Night Football Week 8

Here are the key stats and trends behind our Panthers vs. Packers prediction on the spread for Thursday Night Football on October 29.

  • While the Packers have the 11th-lowest pressure rate (33.0%), the Panthers will be without LG Damien Lewis and RT Taylor Moton.
  • Green Bay’s ground game receives a massive boost against a Carolina defense that ranks 21st in defensive rush DVOA (-6.2%), per FTN.
  • On the other hand, Young and the Panthers’ offense could have some trouble moving the ball against a Packers defense quietly ranked eighth in overall defensive DVOA (-10.4%).
  • Over their last three games, the Panthers have given up an average of 27.7 points per game.
  • Green Bay is 4-0 against the spread (ATS) over its last four games.
  • Carolina is coming off a game in which it had a season-high 4 turnovers, and no team has forced more takeaways (13) than Green Bay.
Lock in your Panthers vs. Packers picks on PrizePicks before kickoff!

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Make Panthers vs. Packers Picks on PrizePicks

It remains to be seen which version of the Panthers we get each week, while two of the Packers’ three losses this season came against talented NFC North rivals. Will Green Bay take care of business at home in Week 8, or will Carolina bounce back from an embarrassing loss?

Don't wait until kick off — make your Panthers vs. Packers picks on PrizePicks now for Week 8 and earn real money if you're right.

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Skyler Carlin is an experienced writer with nearly 10 years of experience writing and editing NFL, NBA, MLB, CFB, CBB, & soccer content for FanDuel Research & USA Today. When he's not writing, he enjoys cooking, watching movies, & playing video games.