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Mexico vs. Great Britain Prediction, WBC Picks – Friday, March 6

Mexico OF Randy Arozarena celebrates after scoring a run against Canada in the World Baseball Classic.
AP Photo/Godofredo A. Vásquez

The bulk of pool play begins in the 2026 World Baseball Classic on Friday, with one of the more intriguing matchups featuring Mexico taking on Great Britain.

Mexico and Great Britain are in Group B along with Brazil, Italy, and the United States. First pitch for Friday’s game is scheduled for 1:00 p.m. ET on FS1.

Below, we'll break down our Mexico vs. Great Britain prediction and picks for Friday afternoon's game. Make your WBC picks on PrizePicks and earn real money if you’re right, including on game winners, spreads, and totals.

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Mexico vs. Great Britain Prediction, Run Line, Over/Under

Friday’s showdown between Mexico vs. Great Britain will mark the first game for both teams in the 2026 WBC.

In the 2023 WBC, Mexico finished atop Group C — just ahead of the United States — with a 3-1 record and advanced to the quarterfinals as a result. Mexico then defeated Puerto Rico 5-4 before losing a 6-5 heartbreaker in walk-off fashion against Japan in the semifinals.

Meanwhile, Great Britain went just 1-3 in the 2023 WBC, with its lone victory coming in a 7-5 triumph against Colombia during the group stage. As a result, Great Britain didn’t advance past the opening round.

Mexico had tremendous success in the last WBC. With a fair amount of MLB talent on its roster this time around, the team could make some noise yet again.

⚾️ Find our USA vs. Brazil Prediction for WBC Today HERE

Mexico vs. Great Britain Winner, Run Line, Over/Under

Mexico enters Friday's WBC matchup 2.5-run favorite, returning a 1.07x payout on PrizePicks Team Picks if they win outright.

Great Britain is a lofty underdog and returns a 7.69x payout if they win outright, per PrizePicks Team Picks, where you can earn money with your picks in 34 states.

  • Run Line: Mexico -2.5 (1.23x payout)
  • Over/Under: 8.5 (1.66x payout on over) 
  • Game Winner Payout: Mexico 1.07x | Great Britain 7.69x

Team Picks data is live as of writing and is subject to change.


Mexico vs. Great Britain Prediction on Winner for 2026 WBC

Here are the key stats to know before locking in your Mexico vs. Great Britain prediction on the winner for Friday, March 6, on PrizePicks.

Team Mexico Preview vs. Great Britain

  • Mexico has a 4-1 record in its last five WBC games, outscoring its opponents 33-19.
  • Mexico has an abundance of pop coming from its outfield, led by Seattle Mariners OF Randy Arozarena.
  • In 2025, Arozarena posted a slash line of .238/.334/.426 while slugging 23 home runs and recording 76 RBIs. Per Fangraphs, the veteran OF posted a .298 BABIP (batting average on balls in play) in 2025.
  • Boston Red Sox OF Jarren Duran could also be a key contributor for Mexico. Duran did have a bit of a down year in the power department, going from 21 to 16 home runs. However, he knocked in a career-best 84 RBIs and posted just a 24.3% strikeout rate.
  • C Alejandro Kirk could see the bulk of the time behind the plate. As a member of the Toronto Blue Jays, Kirk posted a defensive rating of 24.9 in 2025 while belting 15 home runs.

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Team Great Britain Preview vs. Mexico

  • Yankees SS Jazz Chisholm Jr. paces the offensive attack for Great Britain.
  • Chisholm posted a slash of .242/.332/.481, launching 31 home runs during the 2025 season. According to Baseball Savant, he produced a 15.0 barrel rate, ranking in the 91st percentile.
  • OF Trayce Thompson will suit up for Great Britain. Thompson's played seven seasons for the Chicago White Sox, Los Angeles Dodgers, Oakland Athletics, Chicago Cubs, and San Diego Padres.
  • Thompson owns a career slash of .212/.300/.411, hitting 45 home runs and 126 RBIs.
  • Former Philadelphia Phillies SP Vance Worley will be a member of Great Britain’s rotation. Worley pitched eight professional seasons for the Phillies, Minnesota Twins, Baltimore Orioles, and Pittsburgh Pirates and had a 35-36 career record to go along with a 4.09 ERA and a 1.433 WHIP.

Make Mexico vs. Great Britain WBC Picks on PrizePicks

The 2026 World Baseball Classic is in full swing, with Mexico taking on Great Britain on Friday afternoon. Both countries aim to begin the tournament on the right foot.

You can make your World Baseball Classic picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make your predictions on winners, spreads, and tournament winners, now available in 34 states.

Stick around with the Playbook for continued World Baseball Classic predictions, picks, and news.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Chris Bengel is a veteran sports writer with two decades of experience covering the NBA, NHL, and NFL for CBS Sports and 247Sports. He attended Rowan University where he earned a degree in journalism and is a tortured Philadelphia sports fan residing in Harrisburg, PA.

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