Announcing Bigger Payouts
2000x Your Cash Now Available
Announcing Bigger Payouts
2000x Your Cash Now Available
Announcing Bigger Payouts
2000x Your Cash Now Available
Announcing Bigger Payouts
2000x Your Cash Now Available

Mets vs Giants Predictions, Picks – Friday, July 25

Giants 3B Rafael Devers celebrates a hit in an MLB game. Devers is a top PrizePicks MLB pick for Friday. July 25.
AP Photo/Jeff Chiu

An intense East Coast vs. West Coast showdown between two potential National League playoff kicks off this weekend in the Mets vs. Giants. The Giants, led by newly acquired Rafael Devers, play host to the New York Mets and Juan Soto.

On Friday, we'll see the Mets vs Giants at 10:15 p.m. ET to close out a loaded night of MLB games. Below, we'll give you Mets vs Giants predictions and picks for Friday's game, including PrizePicks MLB picks.

The Giants begin a three‑game home stand against the Mets on Friday, owning a 28-20 record at Oracle Park. New York, meanwhile, carries a 22-28 record in road games. This series opener represents the first meeting between the clubs in 2025.

With the All-Star break behind us, every MLB game means more. There is no better time than now to make your MLB predictions on PrizePicks and cash in, including on Mets vs Giants tonight.

Get started on PrizePicks today to get a $50 instantly in Lineups after your first $5 Lineup.

PrizePicks MLB Picks Mets vs Giants: Friday, July 25

Here are the top MLB picks and predictions for PrizePicks today. Use this analysis to build your Lineups on PrizePicks MLB on Friday, July 25. Click to read more about each pick.

Mets P Clay Holmes – 4 Pitcher Strikeouts

Mets vs Giants Predictions - Clay Holmes strikeouts
  • Over his last 110 plate appearances, Mets SP Clay Holmes has surrendered a 4.9% barrel rate, a 40% hard‑hit rate, and kept fly balls down to 13%.
  • Holmes has been tagged for at least two earned runs in each of his last four starts.
  • His strikeout rate has dipped sharply this stretch, falling below 12% over those 110 PAs, and he’s cleared three strikeouts in only one of his last five outings.
  • The Giants own a strikeout percentage of less than 22% against RHP this season.

Giants 3B Rafael Devers – 1.5 Hits+Runs+RBIs

Mets vs Giants Predictions - Rafael Devers hits+runs+rbi
  • In July, 3B Rafael Devers slashed .277 (18-for-65) with two home runs and five doubles, in the midst of a hot streak after a rocky start since being traded from the Red Sox.
  • Against right‑handed pitching this year, in 304 plate appearances, he’s posted a 67% hard‑hit rate, a 16% barrel rate, and a .320+ BABIP
  • Against Clay Holmes specifically, Devers is 2-for-7 in his career, including one of those hits going for a home run.

Giants P Logan Webb – 34.5 Pitcher Fantasy Score

Mets vs Giants Predictions - Logan Webb Fantasy Score projections
  • In his last 134 plate appearances, Logan Webb’s metrics have climbed above his season averages, as he's allowed a 15% barrel rate, a 51% hard‑hit rate, and a 20% fly‑ball rate — a regression closer to where he was statistically prior to this season.
  • Webb has allowed two or more earned runs in five consecutive outings.
  • Over the Mets’ 412 plate appearances against right‑handed pitching, New York has produced a .303 BABIP, a 10%+ barrel rate, a 50%+ hard‑hit rate, and a 30%+ fly‑ball rate.

Make MLB Predictions on PrizePicks

With the Mets vs Giants weekend series, we get matchup between two likely MLB playoff teams, with every game carrying importance.

Whether you're targeting hitters like Rafael Devers or a Logan Webb's fantasy score projection, there are hundreds of projections to make your predictions on PrizePicks.

Just build your Lineup on PrizePicks with your MLB predictions and win real money if your picks are correct. All you have to do is pick More or Less on at least two player projections — like hits or pitcher strikeouts — to win.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions.
Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

Shayne Trail is a Penn State Smeal College of Business graduate, and is the President of the @HallofFameFund (on X) where he positions historically profitable sports trends into investments. Shayne has expertise in all major sports, but writes mostly about NFL, MLB, and NBA for Playbook.

New Player Offer
Get $50 Instantly

In Lineups after you play $5

Play Now
PrizePicks Logomark

Smart picks start here.

Get expert insights, analysis, and news delivered straight to your inbox.

Green checkmark emoji
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
official Partner of

Join the largest squad in Daily Fantasy Sports

Join our Discord
let’s goooo