Mariners vs. Yankees Prediction, MLB Picks for Tuesday, August 11

First pitch in the Seattle Mariners vs. New York Yankees game is set for 7:05 p.m. ET on Tuesday, August 11, with the Yankees entering as home favorites and returning a 1.72x payout if they win, via PrizePicks.

Today’s clash is game one of the second and final three-game series between these two teams this season. The Yankees won the first series in Seattle 2-1. Can the Mariners stop their downtrend by picking up a big series win in the Bronx?

Below, we'll break down our  Mariners vs. Yankees prediction and picks for Tuesday’s MLB game, including the run line, over/under, and key player picks for PrizePicks.

Make your picks for Mariners vs. Yankees on PrizePicks now.

{{mlb_offer_banner="/style-system/ui-components-playbook"}}

Mariners vs. Yankees, Winner Payout, Over/Under – Tuesday, August 11

The Mariners are currently 56-63 and sit 4.5 games behind the Houston Astros for the lead in the AL West. They are on a four-game losing streak, and their season is quickly unraveling before their eyes.

One more poor series in a tough place to play could see them well on the outside looking in of the three AL Wild Card spots.

Seattle sends SP Bryan Woo (3.68 xFIP) to the mound tonight in hopes of bucking the losing streak. Woo is a quality pitcher but has struggled on the road.

The Yankees are 66-52 on the season and are six games behind the Tampa Bay Rays in the AL East. With the Rays not seeming likely to slow down anytime soon, New York's hopes of winning the division may be quickly slipping away. With that said, it still holds a firm grasp on the first Wild Card spot, sitting two games above the Boston Red Sox.

New York has desperately been trying to hold serve without its captain and best offensive player in OF Aaron Judge, who has been sidelined since May 31 with a stress fracture in his right rib. The good news is that Judge has been cleared to return to light, non-baseball activities and is targeting a return for late August/early September.

If the Yankees can get a healthy Judge for the playoffs to pair with their trade deadline acquisitions of 1B Luis Garcia Jr. and OF Heliot Ramos, this team might quickly ascend to the top of the leaderboard in World Series victory odds.

Mariners vs. Yankees Winner Payout, Over/Under – Tuesday, August 11

The Yankees enter Tuesday’s game as home favorites against the Mariners, returning a 1.72x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Mariners vs. Yankees game on PrizePicks.

Play the Mariners vs. Yankees spread or over/under on PrizePicks Team Picks to earn real money — available in 36 states!

Team Picks data is live at the time of writing and is subject to change.

Mariners vs. Yankees Prediction on Winner – 8/11/26

Here are the key game stats and trends behind our Mariners vs. Yankees prediction on the winner for Tuesday, August 11.

Lock in your Mariners vs. Yankees prediction on PrizePicks now.

Unless otherwise noted, data used in this article is from Baseball Savant or FanGraphs.

• The Mariners have been the worst team in baseball against the spread (ATS) with a dismal covering record of 44-75-0 (37%).
• Those struggles have been somehow even more pronounced on the road, evidenced by a 21-36-0 (36.8%) ATS record.
• Neither offense has been good recently, but for the season, the Yankees have been slightly better with a team wRC+ of 102 (12th) compared to the Mariners wRC+ of 99 (16th).
• Without Judge, it's been the Yankees' pitching that's kept them in games. Their bullpen owns the best xFIP in the league over the last two weeks (3.41). That's miles ahead of the Mariners, who are ranked 15th with a bullpen xFIP of 4.24.
• New York could also own the edge in the starting pitcher department tonight with Weathers (3.22 home xFIP) toeing the rubber against Woo (4.20 road xFIP).

Mariners vs. Yankees Picks, Player Stats for PrizePicks: 8/11/26

Here are the top Mariners vs. Yankees picks to target on Tuesday, August 11. Today’s MLB picks for PrizePicks include Bryan Woo and Ryan Weathers.

Mariners P Bryan Woo vs. Yankees: 17.5 Pitcher Outs

• Woo's road ERA (6.71) and xFIP (4.20) are well above his home marks of 1.97 and 3.18, respectively.
• The veteran hurler has failed to record more than 15 outs in each of his last five road starts.
• One of Woo’s greatest strengths as a pitcher is his ability to limit walks. However, on the road against lefties, he owns a 3.41 BB/9.
• The Yankees project to have seven LHB in the lineup tonight, and while they haven't been hitting well as a team, they do rank fourth in baseball in BB% at 9.8%.
• The Mariners are coming off a day of rest, so their bullpen should be readily available if Woo starts to falter in the middle innings of this incredibly important game.

Add Bryan Woo to your PrizePicks Lineup now.

{{mlb_offer_banner="/style-system/ui-components-playbook"}}

Yankees P Ryan Weathers vs. Mariners: 6 Strikeouts

• Weathers has been fantastic for the Yankees this season, with his 9.82 K/9 being by far the highest mark of his career.
• He averages about 0.2 more K/9 at home, and his best split is home against lefties, where he owns a dominant 12.94 K/9.
• The Mariners have a ton of left-handed bats, with four projected to be in today’s starting lineup, even against a dominant LHP in Weathers.
• Weathers faced the Mariners in his first start this season in Seattle, where he struck out 7 batters despite throwing just 77 pitches.

Add Ryan Weathers to your PrizePicks Lineup now.

Make Rays vs. Mariners Picks on PrizePicks

Two teams desperate for a victory will lock horns in the Bronx tonight. Can the Mariners show some fight to compete for the division all the way to the end, or will the Yankees continue to tighten their grasp on the first AL Wild Card spot with victory in front of their home crowd tonight? 

Don’t wait until lock — make your Mariners vs. Yankees picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on MLB game winners, spreads, and over/unders, now available in 36 states.

Stay locked in on Playbook for daily MLB predictions, picks, and news every day all the way through the 2026 MLB World Series.