The Los Angeles Dodgers (27-18) and Los Angeles Angels (16-29) will play the second game of a three-game series on Saturday, May 16, at 9:38 p.m. ET.
On Friday, the Dodgers defeated the Angels 6-0 despite SP Blake Snell being a late scratch due to an elbow injury. Snell is out indefinitely, though Los Angeles believes he can return at some point this season.
Ahead of the first pitch, the Dodgers are road favorites with a 1.66x payout if they defeat the Angels, via PrizePicks Team Picks.
Below, we'll break down our Dodgers vs. Angels prediction and picks for Saturday’s MLB contest, including the run line, over/under, and key player picks for PrizePicks.
Make your Dodgers vs. Angels picks on PrizePicks for Saturday night's game.
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Dodgers vs. Angels Prediction, Winner, Over/Under – Saturday, May 16
For the second game of the series in the battle of L.A. teams, it will be the Dodgers SP Justin Wrobleski (4.84 xFIP across 6 starts and 44.2 IP in 2026) and Angels SP Jose Soriano (3.10 xFIP across 9 starts and 54.1 IP) facing off on the bump.
Wrobleski has been a perplexing pitcher, as he’s enjoyed results with a 2.42 ERA and 0.99 WHIP despite ranking in the second percentile in whiff rate (14.9%) and fourth percentile in strikeout rate (12.4%), via Baseball Savant. However, he’s in the 49th percentile in xERA (4.08) and 26th percentile in xBA (.264), so he could face negative regression soon.
With injuries plaguing their pitching staff right now, the Dodgers may need their loaded lineup to carry the load in most games. Over the last two weeks, the Dodgers’ bats have tallied the seventh-best wRC+ (107), ninth-best wOBA (.325), and eighth-best ISO (.163), per FanGraphs.
Soriano has long been a heavy groundball pitcher, but he’s now residing in the 92nd percentile in whiff rate (32.8%) and 84th percentile in strikeout rate (28.4%) to go along with his 76th percentile groundball rate (50.0%).
The Angels have some pop in their bats with the 13th-best ISO (.151), but they also have the 13th-worst wRC+ (96), 13th-worst wOBA (.314), and highest strikeout rate (26.0%) in the league.
Dodgers vs. Angels Winner Payout, Over/Under – Saturday, May 16
The Dodgers enter Saturday’s game as road favorites vs. the Angels, returning a 1.66x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Dodgers vs. Angels game on PrizePicks.
- Spread: Dodgers -1.5 (2.08x payout)
- Over/Under: 8.5 (1.92x payout on Over)
- Game Winner Payout: Dodgers 1.66x | Angels 2.08x
Play the Dodgers vs. Angels winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!
Team Picks data is live at the time of writing and is subject to change.
Dodgers vs. Angels Prediction on Over/Under – 5/16/26
Here are the key game stats and trends behind our Dodgers vs. Angels prediction on the run total for Saturday, May 16.
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- Wrobleski has surrendered 1 or fewer ER in five of his first six starts this season.
- On the other hand, Soriano has given up 1 or fewer ER in seven of his nine outings in 2026.
- With Soriano’s ability to keep the ball out of the air and his 70th percentile hard-hit rate (35.1%), there have been fewer than 9 total runs scored in eight of his nine starts.
- While the Angels have the seventh-highest walk rate (10.8%) and ISO (.165) against left-handed pitching, Wrobleski is in the 83rd percentile in walk rate (6.2%) and 67th percentile in barrel rate (6.3%).
- Up to this point, the Angels have the fourth-worst rate of hitting the over (31.6%) when playing at Angel Stadium.
- Meanwhile, the Dodgers have the 10th-worst rate of achieving the over (45.0%) when operating as the visiting team.
- Even if Wrobleski has a rough start to the game, the Dodgers’ bullpen can right the ship with the seventh-best xERA (3.53), 10th-best BABIP (.283), and lowest HR/9 (0.51) in baseball.
Dodgers vs. Angels Player Picks, Stats for PrizePicks – 5/16/26
Here are the top Dodgers vs. Angels picks to target on PrizePicks for Saturday, May 16. Today’s MLB picks for PrizePicks include Jose Soriano and Justin Wrobleski.
Angels SP Jose Soriano vs. Dodgers: 5.5 Strikeouts
- Despite Soriano racking up 6 or more Ks in six of his nine starts, this is more of a game where his ground ball tendencies could be handy against a hard-hitting Dodgers squad.
- Against right-handed pitching, the Dodgers have the sixth-lowest strikeout rate (20.8%).
- The Dodgers also possess the second-best wRC+ (120), second-best wOBA (.345), and third-best ISO (.173) in that split.
- Lastly, the Dodgers are disciplined at the plate, boasting the sixth-lowest swinging-strike rate (9.9%).
Add Jose Soriano to your PrizePicks Lineup now.
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Dodgers SP Justin Wrobleski vs. Angels: 2.5 Earned Runs Allowed
- Although Wrobleski could see his metrics dip soon, the Angels have just the 16th-best BABIP (.287) against lefties this season.
- Last year, the Angels had the 12th-worst wRC+ (91), 12th-worst wOBA (.302), and highest strikeout rate (27.0%) when facing southpaws.
- Wrobleski could potentially take advantage of the Angels sporting the 10th-highest soft-contact rate (17.3%) against left-handed pitching.
- While Wrobleski coughed up 7 ER in his most recent start, he allowed fewer than 3 ER in his previous six starts.
Add Justin Wrobleski to your PrizePicks Lineup now.
Make Dodgers vs. Angels Picks on PrizePicks
In the battle of the Los Angeles teams on Saturday, runs could be tough to come by, with Soriano and Wrobleski consistently finding ways to limit loud contact. Will the Dodgers inch closer to completing the sweep over the Angels and extend their winning streak to four games?
Don’t wait until the first pitch happens — make your Dodgers vs. Angels picks on PrizePicks now and earn real money if you’re right.
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