We are just one day away from our first full slate of college football; before that, we'll get eight college football games tonight on Friday, September 4, getting started at 6:30 p.m. ET, with the final games kicking at 9 p.m. ET
Today's college football schedule includes three ranked teams — #7 Miami, #10 Oklahoma, #14 USC — all playing as at least three-score favorites
Below is the full Week 1 college football schedule on Friday night, including how to watch or stream every game, and point spreads via PrizePicks Team Picks — now available in 35 states!
You can make picks on NCAAF game winners and spreads in eligible states, and add Player Picks to the same lineup for even bigger payouts all season long!
Make your Friday Week 1 college football picks on PrizePicks — including winners, spreads, and over/unders!
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College Football Games Today: Week 1 Schedule, TV Channels & Spreads
All NCAAF game times in EST. Spreads and winner payouts are live PrizePicks Team Picks as of posting, but are subject to change.
Payouts below — like 3.44x — represent real-money multipliers on correct picks on PrizePicks Team Picks at the time of writing. For example, a $10 entry on NC State to win at a 2.43x multiplier would pay out $243 if you're right. Payouts are live as of writing but are subject to change.
See live payouts and spreads in the PrizePicks app — new users get $150 if you win your first $5 lineup with code PLAYBOOK!
How to Watch College Football Games Tonight – Friday, September 4
The eight-game Friday slate gets started at 6:30 p.m. ET with San José State vs. Eastern Michigan, streaming on ESPN+ — one of only two games tonight on the pay-to-stream network.
Across the rest of Friday night's games, only one game will air on each of the networks listed: Big Ten Network, SEC Network, ESPNU, FS1, ESPN, and FOX.
The most interesting NCAAF games of the night both get started at 9 p.m. ET. #7 Miami plays its first game with top transfer QB Darian Mensah, traveling cross-country to Stanford in an ACC matchup on ESPN, while #14 USC is a 22.5-point home favorite vs. Fresno State on FOX.
Friday Week 1 Spreads, Winners & Potential Payouts on PrizePicks
The rest of Week 1 is on the PrizePicks board now. In eligible states, you can make picks on college football winners, spreads, and totals. Then add Player Picks to the same lineup for bigger potential payouts.
For the first time ever, you can pick winners on PrizePicks — now's the time to make your move.
Make your College Football picks now on PrizePicks!
College Football Promo Today: Flex Friday Protected Play
Friday’s Week 1 college football slate gives us a rare opportunity to run a Flex Friday Protected Play lineup on games playing tonight, including Oklahoma and USC.
Flex Friday is PrizePicks’ OG weekly promo that gives you a Protected Play promo to use on any sport, any lineup — including CFB picks. Claim the promo, apply it to a lineup, and if it loses, you’ll get Bonus Lineups equal to your loss, so you can run it back again.
To use the promo, opt in through the Rewards tab, build a Flex Lineup, and make sure the Protected Play is turned on before you submit.
Join PrizePicks now and opt in to the Flex Friday Protected Play promo here!
Flex Friday is just the fourth day of PrizePicks' daily promos for Stacked September, running through the first month of football season.
Not sure who to pick tonight? We got you. Hit up Playbook for your Week 1 CFB picks and predictions, including winners, upsets, and players to target.
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Best PrizePicks Promo Code for College Football: PLAYBOOK
New to PrizePicks? It's time to download the app and lock your picks in. Use promo code PLAYBOOK when you sign up, and if you win your first eligible $5+ lineup, you'll get $150 in Bonus Lineups added to your account instantly.
You must use promo code PLAYBOOK for this new user offer, and a $10 minimum first deposit is required to get started.
After a qualifying win, claim the Welcome Bonus Mission in the Rewards tab within seven days, then use your Bonus Lineups within the following seven days — all in the app!
Use promo code PLAYBOOK: Play $5, get $150 in Bonus Lineups if you win. Sign up and make your first college football picks.
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More College Football Week 1 Picks & Predictions for Friday Night
Need expert NCAAF picks and predictions before you lock in your college football lineup tonight? Tap into the Playbook’s Week 1 research from our experts across the top games tonight:
- CFB DFS Picks on PrizePicks for Friday, September 4
- San Jose State vs. Eastern Michigan Prediction, Spread, Picks
- Indiana State vs. Purdue Prediction, Spread, Picks
- Toledo vs. Michigan State Prediction, Spread, Picks
- UTEP vs. #10 Oklahoma Prediction, Spread, Picks
- Best College Football TD Scorer Picks for Week 1 – Friday, Sept. 4
Stay locked in on the Playbook college football home for fresh picks, predictions, spreads, and game previews throughout the 2026 college football season
Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state.Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results.Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.
