Best NFL Anytime TD Scorer Predictions for Week 3 – Omarion Hampton, More

The 2026 NFL season has been full of surprises through just two weeks, as some projected playoff contenders have stumbled out of the gate but other expected cellar-dwellers are faring well in September.

Over a third of the league’s 32 teams are averaging more than 25 points per game, and six have crossed the 30-PPG threshold. With Week 3 arriving, which players could help their respective clubs add to those marks? The Sunday day slate and both Sunday and Monday Night Football figure to see sizable scoring outputs.

Below, we'll highlight our best NFL Anytime TD scorer predictions for PrizePicks in NFL Week 3, including five players who could reach the end zone.

Make your NFL Anytime TD picks for Week 3 on PrizePicks now.

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Best Week 3 NFL Anytime TD Scorer Picks for PrizePicks

Whether you’re looking for excitement in the early-afternoon window, eyeing a late-slate pick, or even holding off for a prime-time matchup, Week 3 has plenty of action to choose from. There are star-studded clashes all throughout the weekend, making way for ample touchdown scorer predictions. 

Anytime TDs on PrizePicks include rushing, receiving, recoveries, and returns. PrizePicks often list Anytime TDs as Demons and Goblins, meaning users can only select "More." For standard projections, users can select “More” or “Less.”

Demons are tougher to win but are the only way to get higher payouts. Meanwhile, Goblins are lower than a standard projection, but they are easier to win, so there’s a lower payout.

Here are the top NFL Week 3 Anytime TD scorer picks to target this weekend, headlined by RB Omarion Hampton, TE Dalton Schultz, and WR Dontayvion Wicks. 

Chargers vs. Bills Anytime TD Scorer Prediction – 1 p.m. ET

Chargers RB Omarion Hampton: 0.5 Anytime TDs

• After logging just 12 snaps on offense in Week 1, Hampton’s involvement spiked to 15 in just the first half of Week 2. He also had a 75% red-zone snap rate vs. the Las Vegas Raiders. 
• The sophomore halfback led all RBs in yards after contact on the weekend and is averaging a whopping 5.4 yards per carry on tries where he’s gotten to the line of scrimmage before being hit.
• Last year’s #22 overall NFL Draft pick is tied for second in the sport with 2 rushing TDs in the red zone. 
• The Bills’ defense is nothing to write home about whatsoever. According to Jefe’s Handiwork, it sits 24th in series conversion rate (80.3%) and 19th in explosive play rate (40.0%). 
• Buffalo has surrendered the sixth-most fantasy points to the RB position (49.2), largely due to giving up 252 combined yards and 4 all-purpose TDs. 

Add Omarion Hampton + Chargers to cover the spread to your PrizePicks lineup now.

Texans vs. Colts Anytime TD Scorer Prediction – 1 p.m. ET

Texans TE Dalton Schultz: 0.5 Anytime TDs (Demon)

• Schultz is coming off an outing that saw him set career-high marks for targets (14), receptions (12), and receiving yards (140). 
• He also ran his most routes since 2021 and entered Week 3 as the TE leader for routes run on the year with 82. 
• Per Next Gen Stats, Schultz had the second-most receiving yards from the slot among all players through two weeks (123). Colts slot CB Justin Walley has ceded 9 receptions for 143 yards and 2 TDs this year, via Pro Football Focus.
• With WR Nico Collins still nursing a hamstring ailment and others like Tank Dell being on injured reserve, there could be plenty of volume coming Schultz’s way again.
• Indianapolis’ defense sits 26th in dropback EPA/play at 0.276, via RBSDM. 

Add Dalton Schultz + Texans to win to your PrizePicks lineup now.

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Raiders vs. Saints Anytime TD Scorer Prediction – 4:25 p.m. ET

Raiders RB Ashton Jeanty: 0.5 Anytime TDs

• There could be some positive regression coming for Jeanty. He trails only Kansas City Chiefs RB Kenneth Walker III and Detroit Lions RB Jahmyr Gibbs for most expected fantasy PPG at the position.
• The second-year man was fourth in percentage of offensive touches through Week 2 (51%) and second in share of red-zone touches (68%). 
• According to 4for4, Jeanty ranks sixth by logging 81.8% of the Raiders’ red-zone rushes to this point.
• The Saints have allowed the seventh-most fantasy points to RBs (46.9), headlined by 237 yards and 3 TDs on the ground. 
• New Orleans’ run defense is porous, ranking 27th in EPA/rush (0.002) and dead last in success rate (59.3%). 

Add Ashton Jeanty + Raiders to cover the spread to your PrizePicks lineup now.

Rams vs. Broncos Anytime TD Scorer Prediction – Sunday Night Football

Rams RB Kyren Williams: 1.5 Anytime TDs (Demon)

• On 28 combined touches in Weeks 1-2, Williams has crossed into the end zone on two occasions — once on the ground and once through the air. 
• After getting 33 more opportunities than RB Blake Corum in the red zone in 2025, Williams has out-earned him 7-0 in 2026. 
• Williams has a 40.3% higher route share than Corum as Week 3’s prime-time bout in the Mile High City approaches. 
• Per Fantasy Points Data, no team has yielded more rushing yards on gap concepts than the Broncos. Williams is a top-10 performer on such tries. 
• Contrary to what many expected coming into the year, Denver is allowing the highest EPA/rush (0.175) in the entire NFL. 

Add Kyren Williams + Rams to win to your PrizePicks lineup now.

Eagles vs. Bears Anytime TD Scorer Prediction – Monday Night Football

WR Dontayvion Wicks: 0.5 Anytime TDs (Demon)

• Per NFL Pro, 5 of Wicks’ 6 Week 2 targets occurred on third and fourth down. He hauled in each of them, and the Bears’ defense is 17th in late-down dropback success rate (42.9%).
• Next Gen Stats reveals that the 11.8 expected points added on those Wicks grabs accounted for the fifth most by a WR in a single game in the last two years. 
• Wicks ranked fifth among WRs in average separation score with a 0.196 mark before Thursday Night Football. 
• Fellow Eagles WR DeVonta Smith (hamstring) is banged up this weekend. RB Saquon Barkley (stinger) is as well, thus potentially freeing up some workload-intensive opportunities. 
• Despite first-round rookie Makai Lemon running more routes than him (63 to 59, via SumerSports), Wicks’ 17.86% target share is considerably higher than his 8.93% split.

Add Dontayvion Wicks + Eagles to cover the spread to your PrizePicks lineup now.

Make NFL Week 3 Picks on PrizePicks

Seemingly countless standout players will take the field on Sunday and Monday, but this group of five might just rise above the rest and find the end zone. From Hampton on Sunday afternoon to Wicks and Co. on MNF, football fans have a surplus of available TD scorer predictions for Week 3.

Don’t wait until kickoff — make your NFL Week 3 picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats (like Anytime TDs), and cash in if you’re right. With Team Picks, you can make predictions on NFL game winners, spreads, and over/unders, now available in 36 states.

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