Fantasy Football Buy Low, Sell High for NFL Week 10: Makai Lemon, Christian McCaffrey

It’s the final stretch of the fantasy football regular season, and this is the ideal time to fine-tune your roster. You can make a deal with another potential playoff team to improve both rosters, or with a cellar dweller looking to unload some players.

Entering Week 10, it's time to assess where fantasy football rosters stand, with trade candidates to help you win your fantasy football championship.

Let’s analyze a group of players to buy low or sell high for NFL Week 10 in fantasy football, paired with how each player could perform based on PrizePicks projections in Week 10.

Make your Week 10 NFL predictions on PrizePicks — including players and game winners!

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2026 Fantasy Football Buy Low Players for Week 10

Here are key buy-low players to consider trading for in Week 10, along with their PrizePicks projections this week.

All stats via PFF, NFL Next Gen Stats, and rankings via FantasyPros.

Eagles WR Makai Lemon – Buy Low

Week 10 Matchup: Bye

The Eagles' playoff chances are pretty much gone, as they’ve lost their seventh straight and have the worst record in the NFC. 

Injuries are a major reason for their struggles. It began with Eagles QB Jalen Hurts being out for the season due to blood clots, but the injury bug has spread through the offense, including WRs Devonta Smith and Dontayvion Wicks missing the last two games.

This has made Makai Lemon the primary receiver, and he has 26 targets over his last three games, resulting in 16 receptions for 185 yards and 1 TD. These aren’t eye-popping numbers, but the volume is encouraging.

The Eagles have moved on from QB Tanner McKee as their starter, and QB Joe Milton made his debut in Week 9 against the Giants. Milton brings mobility that McKee didn’t, and he led the Eagles with 61 rushing yards last week. That ability to evade the pass rush could help him avoid sacks and wait for receivers to get open, which could improve the passing game.

Another factor that could help Lemon is that the Eagles will likely be playing from behind each week. That should give Lemon more targets on a weekly basis.

Commanders WR Antonio Williams – Buy Low

Week 10 Matchup: vs. Giants (Thursday Night Football)

The Commanders are likely out of contention, with the second-worst record in the NFC, but the organization may still have hope for its future with the talent it has. 

The loss of Commanders WR Terry McLaurin is a major blow to an offense that has dealt with injuries throughout the year, including QB Jayden Daniels, who missed two games with a left-elbow injury, and RB Jacory Croskey-Merritt, who is on IR with a groin injury.

The 2026 third-rounder Antonio Williams has been one of the top rookie wide receivers this season, ranking third among rookie receivers with at least 20 targets in reception percentage (74.3%) and PFF offensive grade (70.7).

Williams didn’t do much in Week 9 against the Rams, catching just 3 passes for 25 yards. However, encouraging signs suggest his production is coming. He has seven games with at least 3 receptions, and over the last two games, he’s led the team with 64 routes run and 13 targets.

According to Fulltime Fantasy, the Commanders have the eighth-easiest fantasy strength of schedule for wide receivers for the rest of the season. That could be highly beneficial for Williams, who may become the team’s top receiver in the coming weeks.

Antonio Williams vs. Giants Projections for Week 10

Here are Williams’ projections vs. Giants via PrizePicks — pick More or Less on player stats to cash in every week.

• 43.5 Receiving Yards
• 3.5 Receptions
• 9.5 Fantasy Score
• 0.5 Anytime TDs (Demon)
• 19.5 Longest Reception

Pick Antonio Williams + Commanders to win on PrizePicks now!

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Titans RB Tony Pollard – Buy Low

Week 10 Matchup: @ Jaguars

Tony Pollard has proven over the last couple of weeks that he’s still got it. In Weeks 7 and 8, he combined for 292 yards from scrimmage, 5 TDs, and was the RB1. 

We're hoping a contender will want to trade for Pollard ahead of the NFL trade deadline. It doesn’t make sense for the Titans to keep a 29-year-old RB on a 1-7 team when he’ll be a free agent after this season. 

Pollard’s uncertainty could help you pay a lower price in the trade. You can also argue that you’re taking a risk because of his inconsistency; before his last two games, he had finished in the top 20 only once in six games. 

Tony Pollard vs. Jaguars Projections for Week 10

Here are Pollard’s projections vs. Jaguars via PrizePicks — pick More or Less on player stats to cash in every week.

• 64.5 Rushing Yards
• 12.5 Receiving Yards
• 1.5 Anytime TDs (Demon)
• 2.5 Receptions
• 14.5 Rush Attempts

Pick Tony Pollard + Titans to cover the spread on PrizePicks now!

2026 Fantasy Football Sell High Players for Week 10

Here are some key players to sell high on for fantasy football after overachieving, plus their projections on PrizePicks this week.

Browns WR KC Concepcion – Sell High

Week 10 Matchup: vs. Texans

KC Concepcion has had an underwhelming fantasy season, especially if you thought he'd be the Browns' primary receiver. That has not happened, and he is third on the team in receiving yards (437). 

If you’ve been playing him all season, it’s been a huge disappointment for the most part, with only one finish inside the top 40 in his first six games. Recently, it’s paid off with two finishes inside the top 10. 

In Week 9 against the Saints, he found the end zone for the first time in his NFL career on an explosive 64-yard TD.

A potential concern was that Concepcion ran a vertical route but had to slightly slow his stride to catch it and, as a result, evade some Saints defenders. If Browns QB Shedeur Sanders hits Concepcion in stride, he has a clear path to the end zone. 

It may be unfortunate for Concepcion, but even with an excellent start from Sanders against the Saints, the Browns are going back to QB Deshaun Watson as the starting quarterback after he missed last week with a concussion.

Quarterback play has been a problem for the Browns for most of the season. QB Deshaun Watson has been an average QB, ranking 13th in passing yards per game, 13th in yards per attempt (7.3), and 24th in EPA per dropback (-0.12). 

Concepcion remains third on the pecking order behind TE Harold Fannin Jr. and fellow rookie WR Denzel Boston. Concepcion feels like a weekly boom-or-bust candidate, meaning it feels like a good time to sell for a more consistent player. 

KC Concepcion vs. Texans Projections for Week 10

Here are Concepcion’s projections vs. Texans via PrizePicks — pick More or Less on player stats to cash in every week.

• 46.5 Receiving Yards
• 4.5 Receptions
• 19.5 Longest Reception
• 0.5 Anytime TDs (Demon)

Pick KC Concepcion + Browns to cover the spread on PrizePicks now!

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Panthers TE Darren Waller – Sell High

Week 10 Matchup: @ Saints

The tight end market feels volatile after a renaissance at the position in previous years. Cardinals TE Trey McBride and Raiders TE Brock Bowers are the only two to have scored at least 8 fantasy points in five games this season. Finding a consistent option you can plug in every week is difficult. That’s why you might be able to get a solid return for Darren Waller, though he could be available in some league's waiver wire.

Waller had a huge game in Week 9 against the Broncos, leading the team with 10 targets, 8 catches, and 90 receiving yards. 

While Waller led the way, Panthers QB Bryce Young was phenomenal at spreading the ball around. Five players had at least 4 receptions, including fellow Panthers TE Tommy Tremble, who also found the end zone. 

Waller has not been the clear favorite tight end target. He leads all Panthers tight ends with 35 targets, but Tremble has only 5 fewer targets this season. In the past three games, Tremble led all Panthers tight ends with 9 targets.

Darren Waller vs. Saints Projections for Week 10

Here are Waller’s projections vs. Saints via PrizePicks — pick More or Less on player stats to cash in every week.

• 28.5 Receiving Yards
• 2.5 Receptions
• 15.5 Longest Reception
• 0.5 Anytime TDs (Demon)

Pick Darren Waller + Panthers to cover the spread on PrizePicks now!

49ers RB Christian McCaffrey – Sell High

Week 10 Matchup: @ Cowboys

Having McCaffrey as a sell is tough because he remains an elite dual-threat running back and the RB4. However, this could be a chance to make a blockbuster trade, sending away McCaffrey before his production potentially declines.

We cannot ignore the growing role of rookie RB Kaelon Black. He has 23 carries over his last two games and is averaging an impressive 5.7 yards per carry. In the Week 7 matchup against the Raiders, Black had only 3 snaps than McCaffrey.

CMC has also seen a sharp drop in touches, down from 24.2 touches per game last year to 17.2 this season. The 49ers are using him less in the passing game, which has made McCaffrey a PPR darling throughout his career. Last season, he had just two games with 4 or fewer receptions; this season, he already has three such games.

The 49ers have one goal: win the Super Bowl. McCaffrey has a long injury history, and they need him for a championship run. At 7-1, they currently hold the No. 1 seed in the NFC

If they build a larger lead toward the end of the season, do not be surprised if most of the 49ers' top players are rested for the playoffs. That doesn’t mean missing full games, but just fewer snaps. That would be brutal in fantasy football playoff games.

Christian McCaffrey vs. Cowboys Projections for Week 10

Here are McCaffrey’s projections vs. Cowboys via PrizePicks — pick More or Less on player stats to cash in every week.

• 62.5 Rushing Yards
• 36.5 Receiving Yards
• 1.5 Anytime TDs (Demon)

Pick Christian McCaffrey + 49ers to win on PrizePicks now!

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Make NFL Week 10 Picks on PrizePicks

No matter where your fantasy football team stands, you can always improve. Whether you’re trading for a player who could add value or trading away a player whose value has peaked.

If you want to manage a different lineup each week throughout the NFL season, that's possible as well. Don’t wait until kickoff — make your NFL picks on PrizePicks now and earn real money if you’re right.

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