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Angels vs. Yankees Prediction, MLB Picks for Thursday, April 16

New York Yankees RF Aaron Judge after hitting a home run against the Los Angeles Dodgers.
AP Photo/Mark J. Terrill

Angels vs. Yankees is set for first pitch at 1:35 p.m. ET on Thursday, April 16, with the Yankees returning a 1.31x payout if they win, via PrizePicks.

After pulling off a comeback win in the bottom of the ninth inning on Wednesday, the Yankees will start SP Max Fried (2-0, 1.93 ERA) for this afternoon's matchup. As of early Thursday morning, the Angels hadn't officially named their starter.

Below, we’ll break down our Angels vs. Yankees prediction and picks for Thursday’s MLB game, including the game winner, over/under, and key player picks for PrizePicks.

Make your picks for Angels vs. Yankees on PrizePicks now.

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Angels vs. Yankees Prediction, Winner Payout, Over/Under – Thursday, April 16

The Yankees have been slumping lately, winning just three of their last 10 games. They've won two of Fried’s four starts, with the two losses coming from blown bullpen leads.

New York's bullpen has been shaky, but Los Angeles’ is even worse with a 4.74 ERA and a 1.55 WHIP. They could roll with a bullpen game Thursday because of injuries to their starting rotation.

Closer Jordan Romano might not be available after throwing 21 pitches and blowing a save on Wednesday. He also worked in Monday’s loss, throwing 25 pitches and giving up 3 runs.

Angels vs. Yankees Winner Payout, Over/Under – Thursday, April 16

The Yankees enter Thursday’s game as a home favorite against the Angels, returning a 1.31x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Angels vs. Yankees game on PrizePicks.

  • Spread: New York Yankees -2.5 (2.08x payout)
  • Over/Under: 9.5 runs (1.92x payout Over)
  • Game Winner Payout: Yankees 1.31x | Angels 3.03x

Play the Angels vs. Yankees winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live as of writing and is subject to change.


Angels vs. Yankees Prediction on Winner – 4/16/26

Here are the key game stats and trends behind our Angels vs. Yankees prediction on the winner for Thursday, April 16.

Lock in your Angels vs. Yankees prediction on PrizePicks before the line moves.

  • Although the Yankees are only 5-4 at home so far, they were 50-31 last season.
  • The Angels were just 33-48 on the road last year and are 6-7 away from Los Angeles out of the gate this season.
  • Keeping runners off base continues to be a problem for the Angels. After posting a team WHIP of 1.43 last season, they have an identical mark in 2026.
  • The Yankees ranked fourth in baseball in home OPS (.780) last season.
  • New York may have been unlucky at the plate. Per FanGraphs, they have the third-lowest BABIP (.263) in baseball but are 13th in hard-hit rate (32.9%)
  • The Angels swing and miss a lot, posting the sixth-highest strikeout rate (25.2%) in the majors.

Angels vs. Yankees Player Picks, Stats for PrizePicks: 4/16/26

Here are top Angels vs. Yankees picks to target on PrizePicks for Thursday, April 16. Today's MLB picks for PrizePicks include RF Aaron Judge and 1B Ben Rice.

Yankees RF Aaron Judge vs. Angels Projection: 8.5 Hitter Fantasy Score

  • Judge has at least 1 hit in each of the first three games of this series, including 3 home runs and a double.
  • Although the three-time AL MVP is only batting .235 this season, he's already clobbered 7 home runs.
  • Judge has a paltry .231 BABIP despite having a 25.5% barrel rate. For his career, he has a .347 BABIP and a 22.9% barrel rate.
  • The slugging RF has a career .439 wOBA and a .337 ISO at home.

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Yankees 1B Ben Rice vs. Angels Projection: 5 Hitter Fantasy Score

  • Rice has been one of the Yankees' best hitters, sporting a .488 wOBA and a .353 ISO.
  • After posting a 9.4% walk rate last year, the young left-handed hitter has a 21.2% walk rate through 17 games.
  • Rice makes a lot of loud contact. He has followed up his 55.8% hard-hit rate from last season with a 64.7% hard-hit rate this year. His average exit velocity is 95.7 mph.
  • The 27-year-old spends most of his time batting cleanup, which has helped him rack up 13 RBIs to go along with his 15 runs scored.

Make Angels vs. Yankees Picks on PrizePicks

The Yankees aim to take three of four games from the Angels with their ace on the mound. Judge and Rice attempt to help them win in what could be a bullpen game for Los Angeles. Given the struggles of the Angels' bullpen, both hitters could emerge with juicy stat lines.

Don’t wait until the first pitch — make your Angels vs. Yankees picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

Stay locked in on Playbook for daily MLB predictions, picks, and news every day all the way through the 2026 MLB season.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Mike Barner has been covering fantasy sports since 2007. He specializes in the NBA, NFL, and MLB. He is a two-time finalist for the Fantasy Sports Writers Association Basketball Writer of the Year award and won the 2021-22 FSGA NBA Experts Champions league. In addition to PrizePicks, Mike has written for Sports Illustrated, RotoWire, SportsLine, and more.

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