Top MLB Home Run Picks Today on PrizePicks – Saturday, May 23

May 23, 2026

4 min read

AP Photo/Rick Scuteri
MLB

All 30 MLB teams are in action this weekend, and Saturday’s slate presents plenty of juicy matchups for some potential home run power. Which players could find themselves trotting the bases after hitting a jack?

Here at PrizePicks, we have plenty of home run projections on the board to add to your MLB picks today. Many hitters have already been singled out by users as popular home run picks for the day’s action.

Let’s dive into some of the most-picked MLB home run projections for Saturday, May 23, including what makes each player a potential target for home run predictions. 

Make your MLB home run picks for Saturday, May 23 on PrizePicks now.  

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Top Home Run Picks Today – Saturday, May 23

Nothing gets a crowd or a team going quite like a home run. It’s one of the single most exciting feats in any form of baseball, let alone MLB. With that said, hitting one is also much easier said than done.

It takes more than just strength or bat speed to produce a home run. Hitting a ball out of the park could depend on the dimensions of that park, what the weather is like, how quality a player’s contact is, what launch angle the ball is clobbered at, and much more.

Some players might be better suited than others on Saturday — which ones stand out the most? 

Daily home run projections are listed as Demons on PrizePicks, coming with higher payouts as a result. With that said, home runs can only be selected as “More” than 0.5

Let’s take a look at the most popular home run picks today on PrizePicks. Picks are listed at time of writing.

  1. Phillies DH Kyle Schwarber
  2. White Sox 1B Munetaka Murakami
  3. Astros DH Yordan Alvarez
  4. Cardinals RF Jordan Walker
  5. Blue Jays 1B Vladimir Guerrero Jr.
  6. Orioles 1B Pete Alonso
  7. Phillies 3B Alec Bohm
  8. Mets LF Juan Soto
  9. Royals SS Bobby Witt Jr.
  10. Braves 1B Matt Olson

Three home run picks stand out as potential targets today. Let’s dive into the list, including a weather report from RotoGrinders.

Unless otherwise noted, data used in this article is from Baseball Savant or FanGraphs.


White Sox 1B Munetaka Murakami

White Sox vs. Giants – 4:05 p.m. ET

Giants Starting Pitcher: Adrian Houser

MLB Weather Report: 60 degrees, clear skies, 10 mph southwest wind

  • Murakami’s rookie campaign is off to a tremendous start, as he already has 17 home runs in 50 games.
  • The former NPB superstar owns an elite .309 ISO and a 159 wRC+ to accompany a .404 wOBA.
  • Despite subpar conditions, Murakami might be good enough to cut through some wind. His 114.1 mph max exit velocity and 21.0% barrel rate show that he has tape-measure power in him.
  • Houser surrenders 1.50 HR/9, more than double last year’s mark of 0.72 with two organizations.
  • The 33-year-old pitcher ranks in the eighth percentile for average exit velocity (91.4 mph) and the 19th percentile in hard-hit rate (44.9%). 
Add Munetaka Murakami to your PrizePicks Lineup now.

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Astros DH Yordan Alvarez

Astros vs. Cubs – 2:20 p.m. ET

Cubs Starting Pitcher: Colin Rea

MLB Weather Report: 60 degrees, clear skies, 8 mph north wind

  • Alvarez was made in a lab to produce power numbers, owning a .298 ISO, a .601 SLG, and a 52.0% hard-hit rate.
  • Yordan’s 20.8% home-run-to-fly-ball ratio is his best since 2023 (21.2%).
  • The Astros’ star slugger ranks in the 100th percentile in xSLG (.711) and the 99th percentile in launch angle sweet-spot percentage (46.0%). 
  • Rea routinely gets hit hard, sitting in the second percentile with an average exit velocity of 92.2 mph. He also allows an 11.3% barrel rate, occupying the 16th percentile.
  • While Rea’s 7.9-degree launch angle is the lowest of his career, that barrel rate is the highest he’s ever had in a year with 100+ batted ball events. 
Add Yordan Alvarez to your PrizePicks Lineup now.

Cardinals RF Jordan Walker

Cardinals vs. Reds – 1:10 p.m. ET and 7:15 p.m. ET

Reds Starting Pitcher: Chase Petty

MLB Weather Report: 75 degrees, clear skies, 4 mph west-southwest wind

  • The Walker breakout season rolls on for the Cardinals, as he’s clubbed 13 homers and has a .563 SLG that’s 118 points higher than his debut in 2023.
  • Career-bests in average exit velocity (94.4 mph) and launch angle (14.1 degrees) have Walker barreling the baseball more than ever (16.0%). 
  • Walker is in the 100th percentile in bat speed (78.8 mph), as well as the 93rd percentile in hard-hit rate (51.9%). 
  • According to Ballpark Pal, the weather conditions for games one and two are 25% and 15% more conducive, respectively, to hitting a home run. 
  • Petty, still just 23 years old, has only made one start this year and gave up a home run to go with a squared-up contact split of 30.0%.
Add Jordan Walker to your PrizePicks Lineup now.

Make MLB Home Run Picks on PrizePicks

Saturday features a star-studded lineup of players stepping into the batter’s box. Which ones could club a home run by day’s end? 

Don’t wait until first pitch — make your MLB home run picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

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Skyler Carlin is an experienced writer with nearly 10 years of experience writing and editing NFL, NBA, MLB, CFB, CBB, & soccer content for FanDuel Research & USA Today. When he’s not writing, he enjoys cooking, watching movies, & playing video games.