Friday night’s MLB schedule has some exciting matchups, including Dodgers vs. Brewers in a battle of first-place teams and Yankees vs. Rays in a close American League East race. With plenty of big-name hitters stepping to the plate, who has the potential to send a ball into the stands?
Here at PrizePicks, we have plenty of home run projections on the board to add to your MLB picks today. Several hitters have already been singled out by users as popular home run picks for the day’s action.
Let’s dive into some of the most-picked MLB home run projections for Friday, May 22, including what makes each player a potential target for home run predictions.
Make your MLB home run picks for Friday, May 22 on PrizePicks now.
{{mlb_offer_banner="/style-system/ui-components-playbook"}}
Top Home Run Picks Today – Friday, May 22
Baseball fans dig the long ball, as it’s one of the most exciting parts of baseball. The top sluggers in the game make it look so easy, but there are various factors that go into hitting a home run.
A hitter can possess home run power, but other factors determine whether the ball ends up in the stands. Weather, launch angle, barrel location, ballpark dimensions, pitcher dynamics, and more all go into home run probability. Are some players in better positions than others entering Friday’s slate?
Daily home run projections are listed as Demons on PrizePicks, coming with higher payouts as a result. With that said, home runs can only be selected as “More” than 0.5.
Let’s take a look at the most popular home run picks today on PrizePicks. Picks are listed at the time of writing.
- Yankees RF Aaron Judge
- Astros DH Yordan Alvarez
- White Sox 1B Munetaka Murakami
- Angels CF Mike Trout
- Phillies DH Kyle Schwarber
- Rays 3B Junior Caminero
- Phillies 1B Bryce Harper
- Braves 1B Matt Olson
- Twins CF Byron Buxton
- Yankees 1B Ben Rice
Three home run picks stand out as potential targets today. Let’s dive into the list, including a weather report from RotoGrinders.
Unless otherwise noted, data used in this article is from Baseball Savant or FanGraphs.
Yankees RF Aaron Judge
Rays vs. Yankees – 7:05 p.m. ET
Rays Starting Pitcher: Nick Martinez
MLB Weather Report: 62 degrees, clear skies, 11 mph southeast wind
- One of the 2 lifetime hits Judge has against Martinez is a home run. Martinez has allowed 5 home runs in 7 appearances at Yankee Stadium.
- Yankee Stadium is one of the most hitter-friendly ballparks in baseball, with a home run ballpark factor of 147 this season. That’s the second-highest, per Baseball Savant.
- Judge’s 23.5% barrel rate ranks in the 99th percentile. That is a substantial advantage over Martinez, whose 7.1% barrel rate allowed is only in the 55th percentile.
- The Tampa Bay pitching staff has been prone to giving up the long ball, as its 12.3% home-run-to-fly-ball ratio since May 14 ranks 23rd.
Add Aaron Judge to your PrizePicks Lineup now.
{{mlb_offer_banner="/style-system/ui-components-playbook"}}
Mets LF Juan Soto
Mets vs. Marlins – 7:10 p.m. ET
Marlins Starting Pitcher: Eury Perez
MLB Weather Report: Played in a dome
- Soto is on fire recently, as his 5 home runs since May 14 lead the league.
- The Mets’ star left fielder is a lifetime 1-for-4 against Perez, with that 1 hit being a home run.
- The Marlins’ Friday starter is allowing 1.7 home runs per 9 innings this season, the worst mark of his career.
- Soto’s 18.0% barrel rate (96th percentile), 92.6 mph average exit velo (91st percentile), and 34.4 squared-up rate (91st percentile) make him one of the top power hitters in MLB.
- The four-time All-Star’s 50.5% hard-hit rate, which ranks in the 90th percentile, gives him an advantage over Perez, whose 42.9% hard-hit rate allowed is in the 28th percentile.
Add Juan Soto to your PrizePicks Lineup now.
Phillies 3B Alec Bohm
Guardians vs. Phillies – 6:40 p.m. ET
Guardians Starting Pitcher: Gavin Williams
MLB Weather Report: 59 degrees, 20% chance of precipitation, 9 mph east wind
- After a brutal start to the season (.151 BA, .426 OPS, 1 home run in his first 29 game)s, Bohm has completely turned it around. He has a .339 BA, .985 OPS, and 4 HRs over the last 17 game contests.
- Although Bohm has never taken him deep, he’s a lifetime 3-for-3 against Williams.
- The Guardians’ starter has allowed a home run in seven of his 10 starts this year, and his 1.3 HR/9 is the worst of his career.
- Right-handed hitters have a lot of success at Citizens Bank Park; its 142 home run ballpark factor for righties ranks fifth.
- Bohm’s 35.8% squared-up rate (96th percentile) could be a huge factor against Williams’ 46.7% hit-hard rate allowed (11th percentile) and 91.2 mph average exit velo (11th percentile).
Add Alec Bohm to your PrizePicks Lineup now.
Make MLB Home Run Picks on PrizePicks
A multitude of players could go deep on Friday, but a select group, including three-time MVP Aaron Judge, could have the best opportunity.
Don’t wait until first pitch — make your MLB home run picks on PrizePicks now and earn real money if you’re right.
Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.
Stay locked in on Playbook for daily MLB predictions, picks, and news throughout the 2026 MLB season.
Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state.Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results.Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.




.jpg)
.jpg)