The Detroit Tigers vs. Atlanta Braves game is set for a first pitch at 7:15 p.m. ET on Tuesday, April 28 on TBS, with Atlanta returning a 1.75x payout with a win via PrizePicks.
Atlanta became the first team to reach 20 wins this season, also scoring a league-high 166 runs. The Braves have won eight of nine series and are coming off a home series victory over the Philadelphia Phillies.
The Tigers are the lone team above .500 in the American League Central at 15-14 after capturing the series finale at the Cincinnati Reds on Sunday, 8-3.
Below, we'll break down our Tigers vs. Braves prediction and picks for Tuesday's MLB game, including the winner, over/under, and key player picks for PrizePicks.
Make your picks for Tigers vs. Braves on PrizePicks now.
{{mlb_offer_banner="/style-system/ui-components-playbook"}}
Tigers vs. Braves Prediction, Winner Payout, Over/Under – Tuesday, April 28
The Braves were 14-15 through 29 games last season but have jumped out to an impressive 20-9 mark in 2026. Atlanta has scored at least 5 runs in six of the past seven games while allowing the third-fewest runs (101) in the league.
Detroit has dominated at home with a strong 10-2 mark, but it’s been a different story away from Comerica Park. The Tigers have stumbled to a 5-12 road record, including four consecutive series-opening losses.
In the last 45 regular-season games, Detroit owns an ugly 18-27 record, including an 8-19 away ledger.
Atlanta seeks its ninth consecutive win against Detroit dating back to 2023. The Braves swept the Tigers in Detroit last September, scoring 22 runs in the series.
Tigers vs. Braves Winner Payout, Over/Under – Tuesday, April 28
The Braves enter Tuesday’s game as home favorites against the Tigers, returning a 1.75x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Tigers vs. Braves game on PrizePicks.
- Spread: Atlanta Braves -1.5 (2.56x payout)
- Over/Under: 9.5 (2.08x payout on Over)
- Game Winner Payout: Tigers 2x | Braves 1.75x
Play the Tigers vs. Braves winner or over/under on PrizePicks Team Picks to earn real money — available in 35 states!
Team Picks data is live at the time of writing and is subject to change.
Tigers vs. Braves Prediction on Winner – 4/28/26
Here are the key game stats and trends behind our Tigers vs. Braves prediction on the winner for Tuesday, April 28.
Lock in your Tigers vs. Braves prediction on PrizePicks before the line moves.
- The Tigers have allowed at least 7 runs in three of the past four road series openers.
- Detroit is tied for 21st in batting average against left-handed pitchers (.221) and is facing veteran Martin Perez tonight.
- The Tigers have won each of P Casey Mize’s two home starts but are 0-3 in his three road outings.
- The Braves are slugging .459 against right-handed pitching, trailing only the Los Angeles Dodgers in that category.
- Atlanta averages 7.4 runs per game in nine series openers, including a 17-spot against the Arizona Diamondbacks on April 2.
- Detroit’s WHIP sits at 1.49 on the road (24th), compared to 1.14 at Comerica Park.
Tigers vs. Braves Player Picks, Stats for PrizePicks: 4/28/26
Here are top Tigers vs. Braves picks to target on PrizePicks for Tuesday, April 28. Today’s MLB picks for PrizePicks include SP Casey Mize and 3B Austin Riley.
Tigers SP Casey Mize vs. Braves Projection: 4.5 Strikeouts
- Mize has recorded at least 5 strikeouts in four of five starts and at least 7 Ks three times.
- The former Auburn Tiger owns a career-high strikeout rate of 27.4%, compared to 22.2% last season.
- The right-hander may be tested by this Atlanta offense that ranks 28th in K-rate at 19.1%.
- Mize compiled 5 Ks in nearly 6 innings of a 6-2 home defeat to the Braves last season.
Add Casey Mize to your PrizePicks Lineup now.
{{mlb_offer_banner="/style-system/ui-components-playbook"}}
Braves 3B Austin Riley vs. Tigers Projection: 1.5 Hits + Runs + RBIs
- In five of the past seven games, Riley finished below this projection, including twice against the Phillies.
- Riley has struggled against right-handed pitching, batting .132 with 21 strikeouts and an OPS of .464.
- He dropped out of the cleanup spot this past weekend, batting fifth on Friday and sixth in each of the last two games.
- In the first two innings this year, Riley is hitting 2-for-26 with 1 home run.
- Riley is posting the lowest strikeout rate of his career (20.2%), but his xBA (.224), xSLG (.384), and wOBA (.295) are also career lows.
Add Austin Riley to your PrizePicks Lineup now.
Make Tigers vs. Braves Picks on PrizePicks
It’s a pivotal interleague set in Atlanta tonight between a pair of first-place squads. Can the Braves stay on fire against a Detroit club that has struggled on the road?
Don’t wait until lock — make your Tigers vs. Braves picks on PrizePicks now and earn real money if you’re right.
Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.
Stay locked in on Playbook for daily MLB predictions, picks, and news every day all the way through the 2026 World Series.
