Super Bowl 60, the final game of the 2025-26 season, is set for Sunday at 6:30 p.m. ET on NBC. It features a showdown between the class of the NFC and AFC: the Seattle Seahawks and New England Patriots.
This PrizePicks Cheat Sheet is your ultimate resource for the best Super Bowl 60 matchups and top predictions for QB, RB, WR, and OL vs. DL developments.
Ready to lock in your Super Bowl 60 predictions? Just go to the PrizePicks NFL board, pick your players, and predict if they’ll have More or Less than their projected stats to earn cash if you're right.
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NFL Super Bowl LX Predictions, Matchups & Cheat Sheet
Find the top NFL Super Bowl predictions, picks, matchups to target, and players to target on Sunday below in the PrizePicks Cheat Sheet, including analysis on QBs, RBs, WR vs. CB matchups, and OL vs. DL mismatches.
Best RB Matchups for Super Bowl
Here's the top RB vs. defense matchup to target on PrizePicks NFL this week to help you make your NFL Super Bowl LX picks.
Seahawks RB Kenneth Walker III vs. Patriots Defense
With Zach Charbonnet (ACL) out, fellow Seahawks RB Kenneth Walker III is expected to handle a larger workload. Over his last two games, Walker has seen a season-high 19 rushing attempts in both contests and also logged a season-high snap share.
Walker ranks top 15 in the NFL in yards per attempt at 4.6 and top five in forced missed tackles with 61. While Patriots star interior defensive lineman Christian Barmore excels as a pass rusher, he has been one of the weakest interior run defenses in the NFL, ranking 125th out of 130 qualified players in Pro Football Focus run defense grade.
Advantage Walker? Potentially.
Super Bowl LX Pick for PrizePicks: Kenneth Walker III – 72.5 Rushing Yards
Best WR vs. CB Matchups for Super Bowl
Here are the top WR vs. CB matchups to target on PrizePicks NFL this week to help you make your NFL Super Bowl LX picks.
Patriots WR Mack Hollins vs. Seahawks CB Josh Jobe
If there is one area to attack in the Seattle Seahawks defense, it's CB Josh Jobe. He ranks 94th out of 109 CBs in PFF coverage mark. When targeted, he allows 10.6 yards per reception.
The 5’11” corner will be giving up a significant height advantage to outside wide receiver Mack Hollins, who stands 6'4” and is averaging 12 yards per reception.
Patriots CB Carlton Davis III vs. Seahawks WR Jaxon Smith-Njigba
Avoiding New England Patriots CB Christian Gonzalez may be a clear part of the Seahawks’ game plan, as he's one of the top secondary pieces in the NFL. That could leave some volume up to Carlton Davis III, who has allowed 81 targets and an average of 10.2 yards per reception this year.
Offensive Player of the Year Jaxon Smith-Njigba is coming off a massive 153-yard, 10-reception performance against the Los Angeles Rams and has been the primary driver of the Seahawks offense. He ranks first in the NFL in receiving yards (1,793) and owns a spectacular 128.8 passer rating when targeted, good for sixth.
Super Bowl LX Pick for PrizePicks: Jaxon Smith-Njigba – 93.5 Receiving Yards
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Best OL vs. DL Matchups for Super Bowl
Here are the top OL vs. DL matchups to target on PrizePicks NFL this week to help you make your NFL Super Bowl LX picks.
Seahawks DL vs. Patriots OL
New England’s offensive line has been serviceable overall but is consistently vulnerable in certain areas. Rookie first-round pick Will Campbell has dealt with injuries and struggled with the quick adjustment to the NFL, allowing 26 pressures and committing 7 penalties across 775 snaps.
LG Jared Wilson has surrendered 28 pressures. In the middle, C Garrett Bradbury ranks 34th out of 39 centers in PFF run-blocking grade. RT Morgan Moses has ceded 29 pressures, but the bigger issue has been discipline (8 penalties).
Seattle's defensive line is a top unit in the NFL. The Seahawks are anchored by dominant trench play. Leonard Williams has generated 58 pressures. Off the edge, DeMarcus Lawrence has added 52 pressures. Emerging phenom Byron Murphy has produced 50 interior pressures, too.
Seattle’s ability to collapse the pocket from the inside might directly attack New England’s weakest point.
Super Bowl LX Pick for PrizePicks: Drake Maye – 221.5 Passing Yards
Patriots DL vs. Seahawks OL
Seattle’s offensive line has been steadier than recent metrics would suggest due to some injuries. LT Charles Cross missed time but has been efficient when available, allowing just 24 pressures over 820 snaps.
On the right side, Abraham Lucas has given up 32 pressures, holding up reasonably well against edge pressure. C Jalen Sundell has been a clear bright spot, allowing only 11 pressures and 0 sacks.
While not dominant, the Seahawks’ line has avoided catastrophic breakdowns, particularly in the interior. That stability could limit quick pressures and force New England to win on the perimeter rather than relying on interior disruption.
Best QB Matchups for Super Bowl
Here are the top QB vs. defense matchups to target on PrizePicks NFL this week to help you make your NFL Super Bowl LX picks.
Patriots QB Drake Maye vs. Seahawks Defense
Across his last two playoff games, MVP runner-up Drake Maye combined for just 265 passing yards with an INT. The Seahawks' defense presents another difficult matchup, ranking top 15 in passing yards allowed to QBs and sixth in passing TDs allowed. Seattle's secondary has been particularly stout.
During the regular season, Maye put up 248 passing yards per game. His Super Bowl LX projection comes in roughly 20 yards below his season average, reflecting the strength of the Seattle defense and the prospect of a more constrained passing environment.
Seahawks QB Sam Darnold vs. Patriots Defense
Sam Darnold is coming off perhaps the game of his life against the Los Angeles Rams, where he threw for 346 yards in the NFC Championship Game. The Patriots' defense, however, does sit top 10 in passing yards and TDs allowed to the QB position.
Among QBs with a minimum of 50 plays in the playoffs, Darnold is first in EPA per dropback and first in completion percentage, further reinforcing his efficiency in high-leverage situations. He quietly put together one of the strongest seasons of any signal-caller, finishing fifth in passing yards with 4,048 and ninth in passing touchdowns with 25.
If anyone is built to find some success against New England, it might be Darnold and Co.
Super Bowl LX Pick for PrizePicks: Sam Darnold – 231.5 Passing Yards
Make Seahawks vs. Patriots Super Bowl 60 Picks on PrizePicks
Super Bowl LX is finally here, bringing us one last game-specific opportunity to turn football predictions into rewards. Use this Super Bowl cheat sheet and predictions to sharpen your takes and build out picks on PrizePicks.
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