Saturday College Football Picks for CFB DFS, PrizePicks: Target Ty Simpson

Alabama Crimson Tide QB Ty Simpson runs with the football against Georgia.
AP Photo/Colin Hubbard

The college football regular season is over, and now we get conference championships. This weekend includes nine games, some of which could be vital for College Football Playoff bids. After four matchups on Friday, we now have five on Saturday featuring all the power conferences.

A battle between the top two teams in the country sees No. 2 Indiana take on No. 1 Ohio State in the Big Ten Championship. Even though they are technically the away team, the Hoosiers should feel right at home in Lucas Oil Stadium in Indianapolis.

The SEC Championship, meanwhile, features No. 3 Georgia and No. 9 Alabama. This could be crucial because if the Crimson Tide lose, they might miss the playoffs.

Below, we'll dig into Saturday college football picks for CFB DFS and PrizePicks in our cheat sheet and list the projections for the top players in college football. PrizePicks is the simplest way to win real money with your CFB picks.

Just pick your players, predict More or Less on their projected stats, and cash in if you're correct.

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Saturday College Football Picks for CFB DFS, PrizePicks

Here are the top CFB DFS picks for the conference championships. Use this analysis to make your PrizePicks DFS picks for Saturday's games.

Texas Tech RB Cameron Dickey Projection: 75.5 Rushing Yards

No. 11 BYU vs. No. 4 Texas Tech Pick – 12 p.m. ET

  • RB Cameron Dickey has recorded more than 75 rushing yards in three straight games, including 121 in a 29-7 Week 11 win over BYU. That game against the Cougars produced Dickey’s second-highest rushing total and most carries (23). 
  • Dickey had a season-high nine missed tackles forced against BYU.
  • According to Pro Football Focus, the sophomore had his second-best run grade against BYU (77.6).
  • The Cougars rank 77th in PFF run defense grade.

Virginia WR Trell Harris Projection: 23.5 Yards For Longest Reception

Duke vs. No. 17 Virginia Pick – 8 p.m. ET

  • WR Trell Harris has a 23+ yard reception in back-to-back games and in six of 12 overall.
  • Harris’ 161 receiving yards in a 34-17 Week 12 win over Duke were a career-high. Part of that came from a 56-yard reception.
  • Duke has allowed the second-most 20+ yard receptions (50), via CFB Stats.
  • Virginia ranks 65th in average yards after the catch (3.7). Duke's defense allows 4.8 yards after catch per reception, ranking 132nd.
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Ohio State RB Bo Jackson: 70.5 Rushing Yards

No. 2 Indiana vs. No. 1 Ohio State Pick – 8 p.m. ET

  • RB Bo Jackson has three straight games with more than 100 rushing yards. His five games with 100+ rushing yards are the most from an Ohio State running back since J.K. Dobbins in 2019.
  • The former four-star recruit is 48 yards away from becoming the fifth true freshman in Buckeyes history to run for 1,000+ yards. 
  • Since Week 10, Jackson is 14th in rushing yards (514). Dating back to Week 12, OSU is 38th in run play percentage at 58.7.
  • Indiana has only faced two teams inside the top 30 in rush EPA (Iowa and Oregon) and allowed 80+ total rushing yards to each.

Alabama QB Ty Simpson Projection: 250.5 Passing Yards

No. 3 Georgia vs. No. 9 Alabama Pick – 4 p.m. ET

  • QB Ty Simpson has thrown for more than 250 yards in six of eight games against SEC opponents. That includes 276 yards in the 24-21 Week 5 win over Georgia. His 24 completions in that game were his second-most this year.
  • Including the regular season, conference championship, and playoff, Georgia has allowed an Alabama QB to throw for more than 250 yards in five of their last six matchups.
  • Georgia ranks 77th in completions allowed per game (19.5).
  • Alabama is allowing just a 29.3% pressure rate, which ranks 36th. Georgia sits 94th with a pressure rate of 31.6% on defense.

Miami OH QB Thomas Gotkowski Projection: 174.5 Passing Yards

Miami OH vs. Western Michigan Pick – 12 p.m. ET

  • QB Thomas Gotkowski became the starter in Week 13 after previous Miami OH QB Dequan Finn abruptly left the program to prepare for the NFL.
  • The true freshman has more than 174 passing yards in his only two games where he’s attempted a pass. One of those was against Ball State, which ranks second to last in the MAC in passing yards allowed per game (223.9).
  • Western Michigan is the No. 3 pass defense in the conference and ranks 18th in the nation (175.9).
  • The Broncos finished with the second and third-lowest pass EPA in conference play during Gotkowski's starts in Weeks 13 and 14.
  • WMU is second in the MAC in defensive pass EPA (-0.079).

Make College Football DFS Picks on PrizePicks

With so much at stake, this could become a memorable weekend in college football. Not only will conference champions be crowned, but playoff spots could be determined.

Whether you're watching the SEC Championship featuring Georgia and Alabama or the Big Ten Championship between Indiana and Ohio State, PrizePicks is the best way to cash in on your college football picks.

Just pick your players — including Ty Simpson and Bo Jackson — predict More or Less on their stat projections, and get paid if your picks are correct.

Stay locked in on the Playbook for more CFB DFS picks and college football predictions throughout the 2025 season.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

John is a graduate from Quinnipiac University with a Master’s Degree in Sports Journalism. With almost 15 years working in radio, TV and blogs, it includes stops at ESPN, NBC Sports, and Audacy. Along with being an avid sports fan, he is into fitness and cooking.

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