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PrizePicks MLB Cheat Sheet: MLB DFS Picks – Thursday, June 5

Tigers P Casey Mize (pictured) is a top MLB DFS pick to target on PrizePicks MLB today, including his strikeout projections.
AP Photo/David Zalubowski

The midweek series are wrapping up as we head into another eventful MLB weekend. Trade rumors are starting to pick up as summer baseball is in full force. With an exciting 13-game slate and series finales on Thursday, June 4, we’ll give you the best MLB DFS picks and projections today, including pitchers and hitters for June 5 in the PrizePicks MLB Cheat Sheet.

Highlighting Thursday’s games is a matchup between the Cleveland Guardians (33-27) and New York Yankees (37-23) at 7:05 p.m. ET on MLB Network.

Whether you are targeting Hits+Runs+RBIs or pitcher strikeout projections, there are plenty of ways to win real money on PrizePicks with your MLB predictions. Below, we’ll give you some MLB DFS picks and analysis to help you craft your Lineup today.

MLB DFS Picks & Projections: Thursday, June 5

Here are four of the top MLB DFS picks and projections to target on PrizePicks today. Use this analysis to help you build your MLB lineup on PrizePicks on Thursday, June 5. Click each pick to read more.

Orioles P Zach Eflin — 4.5 Pitcher Strikeouts

Baltimore Orioles vs. Seattle Mariners – 3:40 p.m. ET

PrizePicks MLB Cheat Sheet – Zach Eflin
  • Orioles P Zach Eflin has struggled to strikeout batters this season, producing just 24 strikeouts over 40.1 innings pitched. His 14.9 K% placers him in the bottom 5% of all eligible MLB pitchers.
  • All of the pitches in his arsenal outside of his changeup are at least 2.0 mph under league average velocity.
  • Against right-handed batters, Eflin struggles as he allows a .256 opposing batting average along with a 1.21 WHIP. Eflin will face five right-handed batters in the Seattle Mariner lineups.
  • His strikeout rate vs. lefties is even worse this year, at 12.6%.
  • His Barrel% this season is a career high at 9.3 while his xSLG (.442) and wOBA (.337) are the highest they have been since his second year in the league.

Astros C Yainer Diaz – 0.5 Hitter Strikeouts

Houston Astros vs. Pittsburgh Pirates –  6:40 p.m. ET

PrizePicks MLB Cheat Sheet – Yainer Diaz
  • Astros C Yainer Diaz stats against right-handed pitchers are rough, posting a .215 batting average along with just a .254 OBP this season.
  • Diaz has produced a 42.1 Chase%, which places him in the bottom 2% of all MLB batters while also having a 3.8 BB% that is also bottom 6% of the league.
  • Pirates P Mitch Keller has been lights out against right-handed batters as he maintains a .230 wOBA, WHIP of 0.93, and a K% of 24.6.%

Tigers P Casey Mize — 17.5 Pitching Outs

Detroit Tigers vs. Chicago White Sox – 2:10 p.m. ET

PrizePicks MLB Cheat Sheet – Casey Mize
  • Tigers P Casey Mize is having a career year, posting a 3.11 xERA as well as a 3.84 xFIP. His K% this season against all batters is 21.6%, a career high as well.
  • He is maintaining a .236 OBA while having a .223 xBA this season.
  • The Chicago White Sox also have the second worst batting average in MLB.
  • On top of having a .221 batting average, against right-handed pitching, the White Sox’s average is just .219 with a K% of 25.5.

Cardinals P Matthew Liberatore — 4 Pitcher Strikeouts

St. Louis Cardinals vs. Kansas City Royals – 7:45 p.m. ET

PrizePicks MLB Cheat Sheet – Matthew Liberatore
  • Cardinals P Matthew Liberatore has either tied or topped this projection in all but one game this season, including a game against the Royals where he struck out five batters in six innings.
  • Liberatore has produced a Chase% of 33.5 which is in the top 8% of all pitchers while also keeping walks to a minimum with a 3.5 BB%.
  • He has also managed a career high in K% at 21.5 while also having a career low in wOBA at .270.

Make Your MLB DFS Picks on PrizePicks

With the NHL and NBA Playoffs wrapping up, there is no better time to lock in on MLB DFS on PrizePicks. Each day brings more opportunities, especially on a day like Thursday, when 26 of 30 teams are in action.

Build your MLB Lineup on PrizePicks with your favorite MLB projections and win real money if your picks are correct. All you have to do is pick More or Less on at least two player projections — like hits or pitcher strikeouts — to win.

Stay locked in on the Playbook all season long for MLB DFS picks every day.

Get in the Game! Sign up for PrizePicks and win real money with your picks. Play $5 to get $50 free with promo code PLAYBOOK.

about the author

Austin Wells is a social media manager and content strategist. He’s from Covington, Georgia, and graduated in 2024 with a degree in Business Administration, concentration in marketing. Austin loves all things Philadelphia, including the Eagles and the Sixers, but his MLB fandom lies with the Yankees. He collects baseball cards and has the ultimate goal of visiting every MLB and NFL stadium.

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