Phillies vs. Red Sox is set for first pitch at 6:45 p.m. ET on Tuesday, May 12, with the Phillies returning a 1.63x payout if they win, via PrizePicks.
The Phillies turn to veteran P Zack Wheeler (1-0, 3.12) to start this matchup. While Philly will have a known commodity on the mound, the Red Sox hadn't officially named their starter as of Tuesday morning. They're expected to deploy an opener, with Brayan Bello (2-4, 7.44 ERA) potentially to follow and pitch multiple innings.
Below, we’ll break down our Phillies vs. Red Sox prediction and picks for Tuesday’s MLB game, including the game winner, over/under, and key player picks for PrizePicks.
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Phillies vs. Red Sox Prediction, Winner Payout, Over/Under – Tuesday, May 12
After disappointing starts, both the Phillies and Red Sox fired their respective managers. The Red Sox remain in last place in the American League East with a 17-23 record and are 5-5 over their last 10 games.
The Phillies also have a losing record at 19-22, but they've been playing better lately. Since a rainout against the San Francisco Giants on April 30, they're 9-3 over their last 12 games. They also scored at least 6 runs in seven of those nine victories.
Phillies vs. Red Sox Winner Payout, Over/Under – Tuesday, May 12
The Phillies enter Tuesday’s game as a road favorite against the Red Sox, returning a 1.63x payout if they win outright, via PrizePicks Team Picks.
Here are the full payouts for the Phillies vs. Red Sox game on PrizePicks.
- Spread: Philadelphia Phillies -1.5 (2.04x payout)
- Over/Under: 8.5 runs (1.96x payout on Over)
- Gamer Winner Payout: Phillies 1.63x | Red Sox 2.12x
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Team Picks data is live as of writing and is subject to change.
Phillies vs. Red Sox Prediction on Winner – 5/12/26
Here are the key game stats and trends behind our Phillies vs. Red Sox prediction on the winner for Tuesday, May 12.
Lock in your Phillies vs. Red Sox prediction on PrizePicks before the line moves.
- The Phillies being more productive at the plate lately puts the Red Sox in a difficult position. Boston’s lineup has been anemic, scoring the fourth-fewest runs in baseball.
- Philadelphia has a significant advantage in the power department. The team has gone deep 49 times this season, which ranks ninth in baseball. Boston’s 29 home runs are the third-fewest.
- The Red Sox actually have a better record on the road (10-11) than at home (7-12).
- The Phillies are 3-0 with Wheeler on the mound this season.
- Wheeler has looked great since returning from injury, allowing 3 or fewer runs in each of his outings. He may no longer be on any sort of pitch restrictions, especially considering he threw 98 of them in his last start.
Phillies vs. Red Sox Picks, Player Stats for PrizePicks: 5/12/26
Here are top Phillies vs. Red Sox picks to target on PrizePicks for Tuesday, May 12. Today's MLB picks for PrizePicks include DH Kyle Schwarber and SS Trevor Story.
Phillies DH Kyle Schwarber vs. Red Sox Projection: 1.5 Hits + Runs + RBI
- Schwarber has hit a home run in four straight games. During that span, he's gone 7-for-19 with 5 home runs, 7 RBI, and 5 runs scored.
- Known for his power, the lefty slugger has finished with at least 100 RBI and 100 runs scored in each of the last three seasons.
- Bello has struggled through seven appearances this year, posting a 7.44 ERA that's backed by a 6.91 xERA. A large reason why is he's surrendered 8 home runs in 32.2 innings.
- Per FanGraphs, opposing hitters also have a 12.7% barrel rate against the righty hurler.
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Red Sox SS Trevor Story vs. Phillies Projection: 4.5 Hitter Fantasy Score
- Story is off to a slow start, recording a .234 wOBA and a .084 ISO.
- Strikeouts have been a big issue for the shortstop. He's struck out at least twice in five of his last six games, leaving him with a 33.3% K-rate for the season.
- Story has been limited to a .220 wOBA against right-handed pitchers and has a 34.2% strikeout rate against them.
- Wheeler has a 26.5% K-rate across three starts and hasn’t finished with a mark below 26.0% since 2020.
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The Phillies aim to stay hot when they face the Red Sox in Boston on Tuesday. Schwarber has an excellent opportunity to remain productive with Bello expected to log multiple innings, while Story could struggle to make contact versus Wheeler.
Don’t wait until the first pitch — make your Phillies vs. Red Sox picks on PrizePicks now and earn real money if you’re right.
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