The NFL preseason officially wraps up on Saturday, August 29, showcasing a doubleheader on NFL Network. The Lions vs. Colts kick off the festivities at 1:00 p.m. ET, followed the Bears vs. Titans with a 6:00 p.m. ET kick-off.
The Colts and Titans are expected to feature starters in some capacity, while the Lions and Bears have more unclear plans for Saturday.
Below, we’ll break down each team heading into today’s NFL preseason action. Let’s circle a pair of NFL preseason predictions for PrizePicks.
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Lions vs. Colts Prediction on Over/Under for NFL Preseason – Saturday, August 29
Lions head Dan Campbell has a track record of being cautious in the preseason. Ahead of last week’s matchup with the Commanders, Campbell suggested Detroit could play starters, but the Lions mostly rested first-string players, featuring a few key players on defense.
No clear report has emerged for Detroit’s plan vs. the Colts. Considering last week’s mirage concerning starters, Campbell is likely in line to do the usual—give his key starters rest.
Ahead of their season-opening game vs. the Saints on September 13, the Lions are mostly healthy, but TE Sam LaPorta’s hip injury remains a clear concern.
The Colts, on the other hand, are expected to feature starters on Saturday. As usual, the starters won’t have a full role, with head coach Shane Steichen citing 8 to 12 plays as a target. That could max out at two series, depending on how the units performance.
Check out our full Lions vs. Colts prediction HERE!
Steichen even pointed to WR Keenan Allen and DT DeForest Buckner as veteran starters who will see playing time in the final preseason contest. However, Indianapolis will not roll out all starters, as QB Daniel Jones and RB Jonathan Taylor are expected to rest.
Through two preseason games, the Lions have posted only 15.5 points per game (PPG)—a far cry from 2025’s 28.3 PPG (fourth). Since 2025, Detroit is 2-4 in preseason games.
The Colts haven’t been any better with a 1-3-1 preseason record since 2025. Plus, Indy has recorded only 9.5 PPG over its last two preseason contests. While some starters will be on the field, the offense could still lack efficiency considering Jones and Taylor will be absent.
With each team struggling to score in the preseason, the over/under is only 35.5 on PrizePicks Team Picks. Here’s the full list of payouts for today’s game, including winner payouts, the spread, and the total.
Payouts show potential returns on correct Team Picks predictions. A 2x payout returns $200 on a $100 entry. Lower multipliers reflect outcomes users are picking as more likely. Payouts are live as of writing and subject to change.
Lock in your Lions vs. Colts prediction on PrizePicks before tonight’s NFL preseason game.
Bears vs. Titans Prediction on Winner for NFL Preseason – Saturday, August 29
Among the four teams in action today, the Titans will likely display starters for the most snaps. In their first two preseason games, QB Cam Ward posted 22 and 19 snaps, a solid workload for the preseason.
Ahead of Saturday’s clash with the Bears, head coach Robert Saleh suggested starters could be in line for another 20 to 25 plays. This strategy has directly led to a 2-0 preseason record, with Tennessee winning its first two games, 19-13 and 19-16.
The starting offense has yet to find its groove, though, as Ward is averaging 6.9 yards per passing attempt and 63.0 passing yards per game. Pro Football Focus also gives the second-year QB a concerning 29.1 player grade over 41 preseason snaps.
Furthermore, rookie WR Carnell Tate has yet to log a catch in the preseason. But that isn’t slowing the hype, with the No. 4 pick dominating the Bears during joint practice this week.
After posting 16.5 snaps per game in the first two preseason games, Titans WR Wan’Dale Robinson could sit this one out following an injury scare in joint practice.
Staying on the injury topic, Chicago CB Jaylon Johnson and CB Tyrique Stevenson each suffered injuries during practice this week. Plus, Bears WR Luther Burden III continues to recover from a groin injury sustained in early August.
Head coach Ben Johnson did not give a clear plan ahead of today’s preseason finale.
Last year, Chicago featured starters in the final preseason game, with QB Caleb Williams recording 28 snaps. However, the Bears did not have joint practice ahead of 2025’s final preseason matchup. After battling with the Titans in practice this week, Johnson may elect to rest most starters this evening.
Considering Chicago’s unknown plan for starters, Tennessee is a 2.5-point favorite for today’s preseason bout. Check out winner payouts, the spread, and over/under for the Bears vs. Titans, per PrizePicks Team Picks.
Lock in your Bears vs. Titans prediction on PrizePicks before tonight’s NFL preseason game.
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Make NFL Preseason Picks on PrizePicks
The Colts and Titans headline the final day of preseason football, with each team expected to feature starters. That should provide advantages for NFL preseason predictions—especially when Tennessee could play starters for over 20 plays.
Don’t wait until lock—make your NFL preseason picks on PrizePicks now and earn real money if you’re right.
Week 1 of the NFL regular season begins on September 9, and the NFL board is already open on PrizePicks Team Picks. That includes NFL predictions for the Super Bowl winner, divisional winners, win totals, and more on PrizePicks Team Picks—available in 36 states!
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