You weren’t dreaming — the NFL is officially back and here to stay. Following Week 1’s glorious full Sunday slate, we’re running it back with 14 games of nonstop NFL Week 2 matchups, beginning at 1:00 p.m. ET and through the Colts vs. Chiefs kicking off at 8:20 p.m. ET.
While Sunday Night Football is always in the spotlight, several NFL Week 2 games stand out as today’s best matchups — especially in the 1:00 p.m. ET slot. For example, the Vikings and Bears battle in an NFC North clash, while the Bengals vs. Texans highlight two potential playoff contenders in the AFC.
Let’s look at the full NFL Week 2 schedule for Sunday’s games, how you can watch each matchup with the TV channel, and current spreads via PrizePicks Team Picks.
You can make picks on NFL winners, spreads, totals, and more in eligible stats. Plus, users can add Player Picks to the same lineup for even bigger payouts all season long!
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NFL Games Today: Week 2 Schedule, TV Channels, & Spreads
Each kickoff is listed in Eastern Time. PrizePicks features spreads and winner payouts for every NFL Week 2 matchup on Sunday, and each payout is subject to change.
As usual, every NFL is game is accessible. Sunday Night Football is on NBC, while the rest of today’s contests are televised by FOX and CBS.
However, which games you get depends on your location. For example, if you reside in Cincinnati, getting the Bengals game should be no problem. Check out today’s NFL broadcast map for Week 2, per 506 Sports.
If you want every single NFL game with four matchups on at all times, NFL Sunday Ticket on YouTube is a way to never miss a game.
Alongside Sunday Night Football, FOX’s America’s Game of the Week is between the Commanders and Cowboys at 4:25 p.m. ET.
Payouts below, like 2x, represent real-money multipliers on correct picks on PrizePicks Team Picks at the time of this writing. For example, a $100 entry on the Texans to win at a 1.61x multiplier would pay out $161 if you’re right.
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How to Watch NFL Games Today – Sunday, September 20
As usual, Sunday’s NFL schedule begins at 1:00 p.m. ET, featuring most of today’s action. In fact, eight of 14 games today take place in the 1:00 p.m. ET slot.
Then, two matchups kick off at 4:05 p.m. ET, quickly followed by three 4:25 p.m. ET games. Finally, the day wraps up under the lights with Sunday Night Football beginning at 8:20 p.m. ET.
The Giants vs. Rams close the NFL Week 2 slate tomorrow at 8:15 p.m. ET on Monday Night Football.
The 1:00 p.m. ET schedule features two divisional matchups: Panthers vs. Falcons and Vikings vs. Bears. Elsewhere, the Eagles (-6.5), Buccaneers (-7.5), and Ravens (-7.5) are notable favorites for point spreads on PrizePicks.
Baltimore hosting the Saints at 1:00 p.m. ET on CBS could draw interest, as New Orleans fell 31-30 as 7.5-point underdogs vs. the Lions in Week 1. Saints WR Chris Olave (hamstring) and EDGE Chase Young (calf) are expected to play, adding to New Orleans’ chances.
Perhaps the top matchups are the Bengals vs. Texans (CBS) and Vikings vs. Bears (FOX) duking it out among the first eight NFL games of the day.
Then, CBS features two battles at 4:05 p.m. ET: Jaguars vs. Broncos and Raiders vs. Chargers. The Commanders vs. Cowboys (FOX), Seahawks vs. Cardinals (FOX), and Dolphins vs. 49ers (FOX) all kick off at 4:25 p.m. ET, followed by the Colts vs. Chiefs at 8:20 p.m. ET on NBC’s Sunday Night Football.
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Must-Watch NFL Week 2 Games Today – Sunday, September 20
If you’re preparing your four-game watch on Sunday Ticket for the 1:00 p.m. ET slate, here are the games you should circle.
Best NFL 1pm Games Today
- Vikings vs. Bears – FOX
- Steelers vs. Patriots – CBS
- Packers vs. Jets – FOX
- Bengals vs. Texans – CBS
After sifting through a busy 1:00 p.m. ET schedule, choosing a couple of 4:05 and 4:25 p.m. ET games takes little brainpower. And as always, we’ve got one game on tap for the primetime slot.
Best NFL 4pm Games Today
- Jaguars vs. Broncos – CBS
- Commanders vs. Cowboys – FOX
- Seahawks vs. Cardinals – FOX
NFL Week 2 Sunday Night Football
- Colts vs. Chiefs – NBC
Week 2 NFL Spreads, Winners, Payouts Today on PrizePicks
Among today’s 14-game NFL Week 2 schedule, the tightest spreads belong to the Panthers vs. Falcons, Bengals vs. Texans, and Jaguars vs. Broncos.
While the NFC South is likely gearing up to be the league’s worst division yet again, this is a key battle with the Panthers -2.5 on the road. Meanwhile, the Texans (-2.5) and Broncos (-2.5) are slight home favorites in two of this week’s best matchups.
The Packers (-3.5) are favorites vs. the Jets, and the Cowboys are listed as 3.5-point favorites against the Commanders.
Today’s most lopsided spread by a mile features the 49ers as 12.5-point favorites against the Dolphins. Miami in massive underdog roles is something we will likely get accustomed to throughout 2026.
The next highest spreads via PrizePicks are the Ravens (-7.5) and Buccaneers (-7.5) in home games.
Check out the full NFL Week 2 board on PrizePicks, with picks available for every game. In eligible states, you can now pick NFL winners, spreads, and totals, paired with Player Picks in the same lineup for bigger potential payouts.
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Across a full 14-game slate on Sunday, the Vikings vs. Bears and Bengals vs. Texans could start our day with a bang, followed by the Jaguars vs. Broncos and Commanders vs. Cowboys catching the eye. Finally, the Colts vs. Chiefs wrap up Sunday under the lights, followed by the Giants vs. Rams on Monday Night Football.
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Keep it locked in here with the Playbook for continued NFL picks, predictions, and news all season long.
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