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Top MLB DFS Picks Today: Ohtani, Taijuan Walker, & More | 8/27/25

Dodgers SP Shohei Ohtani is a top MLB DFS for PrizePicks today as he takes the mound vs. the Reds tonight on Wednesday, August 27.
AP Photo/Jayne Kamin-Oncea

Wednesday’s massive 15-game MLB slate features several playoff-implicating matchups, including a crucial Phillies vs. Mets showdown with Taijuan Walker on the mound.

Dual-position superstar Shohei Ohtani and the Dodgers take on the Reds, while hard-throwing rookie Chase Dollander and the Rockies head down to Houston to battle the Astros, trying to hold their division lead over the Mariners.

We'll give you the best MLB DFS picks and player projections to target on PrizePicks MLB for Wednesday, August 27, including hitters and pitchers for your Lineups.

⚾️ Get $50 instantly in Lineups after your first $5+ Lineup for your MLB Picks — Use Promo Code: PLAYBOOK

MLB DFS Picks Today: Wednesday, August 27

Here are the top MLB DFS picks and projections for PrizePicks today. Use this analysis to build your Lineups on PrizePicks MLB on Wednesday, August 27. Click to read more about each pick.


Pirates OF Oneil Cruz Projection: 1.5 Hits+Runs+RBIs

  • Cardinals Sonny Gray has allowed a 10% barrel rate, 46% hard-hit rate, and nearly 30% fly ball rate across his last 68 plate appearances vs. left-handed hitters.
  • Pirates lefty Oneil Cruz returns from the IL showcasing elite power metrics against right-handed pitching: 70% hard-hit rate, 21% barrel rate, and 25% fly ball rate.
  • Against right-handed fastballs—Gray’s most-used pitch—Cruz owns a 74% hard-hit rate, 30% fly ball rate, and 19% barrel rate.

Phillies P Taijuan Walker Projection: 19.5 Pitcher Fantasy Score

Taijuan Walker Projections
  • In Taijuan Walker’s last 114 plate appearances, he's allowed a 7.5% barrel rate, 49% hard-hit rate, and 20% fly ball rate.
  • Over his last two starts, Walker has surrendered 5 earned runs.
  • The Mets have posted a .283 BABIP, 56% hard-hit rate, 10% barrel rate, and 20% fly ball rate in their last 565 plate appearances vs. RHP.
  • Mets 1B Pete Alonso has crushed Walker historically, going 5-for-18 with 3 HRs and 2 doubles and will give him trouble.
  • Walker has averaged 24.4 fantasy points per game over his last five games — but all starts came against much weaker offenses.

Dodgers P Shohei Ohtani Projection: 5.5 Strikeouts

  • Over his last 68 plate appearances on the mound, Shohei Ohtani has tossed a 32.4% strikeout rate — 2% higher than his season average.
  • He also owns a dominant 29.7% whiff rate and 15% swinging strike rate, showcasing great stuff.
  • The Reds lineup features 3 hitters — Matt McLain, Elly De La Cruz, and Austin Hays — each with strikeout rates over 30% in their last 55 PAs.

Rockies P Chase Dollander Projection: 2.5 Earned Runs 

Chase Dollander Projections
  • In his last 69 plate appearances on the mound, Chase Dollander has allowed an 11% barrel rate and nearly a 30% fly ball rate.
  • Dollander has failed to complete 5 innings in each of his last 2 starts, allowing 11 earned runs combined.
  • The Houston Astros have a .303 wOBA in over 2,600 plate appearances this season vs. right-handed pitching.
  • Dollander is averaging 4.2 earned runs allowed across his last five games.

Make MLB DFS Picks on PrizePicks

Wednesday's huge 15-game slate provides plenty of MLB action to make your predictions as we get into the heat of the MLB playoff chase.

Just build your MLB DFS Lineup on PrizePicks with your favorite MLB players and win real money if your picks are correct. All you have to do is pick More or Less on at least two player projections — like Hits+Runs+RBIs or pitcher fantasy score — to win.

Whether you’re going with pitchers or hitters, there’s always real money sports action waiting for you on PrizePicks. Stay locked in on the Playbook all season long for MLB DFS picks for PrizePicks every day.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

Shayne Trail is a Penn State Smeal College of Business graduate, and is the President of the @HallofFameFund (on X) where he positions historically profitable sports trends into investments. Shayne has expertise in all major sports, but writes mostly about NFL, MLB, and NBA for Playbook.

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