MLB DFS Picks Today – Top PrizePicks Plays, 5/8/25

Nearly a fourth of the MLB season is over and the true contenders are starting to prove themselves. Thursday’s games provide us with a mixture of competitive matchups as well as some expected blowouts you can capitalize on in MLB DFS.

We’ll give you the best MLB DFS picks for Thursday’s MLB games, including pitchers, hitters, and a home run pick for May 8 for PrizePicks MLB.

Highlighting Thursday’s games is the Phillies vs. Rays on MLB Network at 7:05 pm ET.

Whether you are picking Lineup filled with pitcher picks or player hits, there are plenty of ways to win real money on PrizePicks. Below, we’ll give you five expert MLB DFS picks to help you craft your Lineup today.

MLB DFS Picks on PrizePicks: Thursday, 5/8

Here are five of the top MLB DFS picks for PrizePicks today. Use this analysis to help you build your MLB lineup on PrizePicks on Thursday, May 8. Click each pick to read more.

• Tigers P Casey Mize — 4.5 Strikeouts
• Angels P Jose Soriano — 17.5 Pitching Outs
• Rays 1B Curtis Mead — 0.5 Hitter Strikeouts (Goblin)
• Reds 2B Matt McLain — 1.5 Hitter Strikeouts
• Home Run Pick: Phillies RF Nick Castellanos

Tigers P Casey Mize — 4.5 Strikeouts

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Time: 3:10 p.m. ET

• The Rockies are the worst in the MLB in hits (247), runs (112), and batting average (.213).
• Against right handed pitching, the Colorado Rockies post only a .215 average and a strikeout rate of 30.1%.
• Tigers P Casey Mize has only allowed 11 earned runs across his six starts this season with over 36 innings pitched, he has also posted a career best WHIP this season (1.09).
• Mize has at least five strikeouts in three of his six starts this season.
• Miza has reverse splits when it comes to strikeouts; he’s striking out 26.9% of left-handed batters this year. He’ll face five lefties in the Rockies lineup today.

Angles P Jose Soriano — 17.5 Pitching Outs

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Time: 9:38 p.m. ET

• Angels P Jose Soriano has only managed to reach this outs projection once out of his last four games started.
• Blue Jays post a .258 batting average when facing right-handed pitchers at home along with a sub-20% strikeout rate.
• In games in which Soriano has allowed two or more runs this season, he has not managed to reach 18 pitching outs.
• This season he has allowed a career-worst 3.83 ERA.

Rays 1B Curtis Mead — 0.5 Hitter Strikeouts (Goblin)

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Time: 7:05 p.m. ET

• Across 32 at-bats this season, Rays 1B Curtis Mead has a batting average of .125, combined with 9 strikeouts (28% strikeout rate) against left-handed pitching.
• Mead has struggled heavily this season with a .151 average and a .233 OBP across all plate appearances.
• Phillies P Jesus Luzardo is tied for the 17th most strikeouts in the MLB, and fifth amongst pitchers with seven starts this season.

Reds 2B Matt McLain — 1.5 Hitter Strikeouts

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Time: 7:15 p.m. ET

• Reds 2B Matt McLain has a .150 batting average this season against right-handed pitchers and a 40% strikeout rate.
• Braves P Spencer Schwellenbach strikes out just over 26% of the right-handed batter he faces along with allowing just a .206 batting average.
• Schwellenbach has produced a 28.3% Whiff rate, 21.6 K%, and a 32.3 chase rate this season. 

Home Run Pick: Phillies RF Nick Castellanos (Demon)

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Time: 7:05 p.m. ET

• Rays P Ryan Pepiot is below MLB average in Barrel% (10.3) and Hard-Hit% (41.9) allowed.
• Phillies RF Nick Castellanos is above MLB average in slugging (.484), average exit velocity (90.4), hard-hit% (43.6), and sweet-spot% (48.2).
• Pepiot gets dominated against right-handed batters, allowing a .321 batting average, and .593 slugging. 
• Pepiot is surrendering a 39.5% fly-ball rate and 35.9% hard-hit rate to right-handed batters, prime for home-run hitting.
• Pepiot is giving up 1.89 HR/9 to righties this year, and a career high HR/9 rate.

Make MLB DFS Picks on PrizePicks

As we wrap up these midweek series along with the first quarter of the MLB season, there’s no better time to get in on the real money action on PrizePicks.

Build your MLB Lineup on PrizePicks with your favorite MLB players and win real money if your picks are correct. All you have to do is pick More or Less on at least two player projections — like hits or pitcher strikeouts — to win.

Head to the PrizePicks MLB board, lock in your picks, and get in on real money action before the MLB games start today.

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