MLB DFS Picks Today: Fantasy MLB Picks for Wednesday, 4/30/25

April 30, 2025

By: John Supowitz

Matt Olson is a top MLB DFS Pick today for fantasy baseball on PrizePicks, as the top home run pick of the day in the Braves vs. Rockies game.

Kevin C. Cox/Getty Images

The best thing about Wednesday baseball is you’ve got MLB games throughout the day, as many teams play early with a travel day coming. Below, we’ll focus on the afternoon and night games for the best MLB DFS picks today.

Wednesday’s best MLB DFS picks include pitchers and hitters to target on PrizePicks, plus a home run prediction for fantasy baseball. The top games include the Yankees vs. Orioles on Prime Video at 6:35 p.m. ET, and Matt Olson and the Braves vs. the Rockies at 3:10 p.m. ET.

You can combine these MLB DFS picks with today’s MLB Discount Dogs promo on PrizePicks — two pitchers have reduced strikeout projections all day long, making their More projection easier to cash.

Below are five picks to help you build your winning lineups for Thursday's MLB game.

Don’t forget to head to the PrizePicks MLB board, lock in your picks, and submit your Lineup to get in on the real money MLB action before the first pitch.

MLB DFS Picks on PrizePicks: Wednesday, 4/30

Here are the top MLB DFS picks and predictions for PrizePicks today. Use this analysis to build your Lineups on PrizePicks MLB on Wednesday, April 30. Click to read more about each MLB DFS pick.

Orioles P Cade Povich — 4.5 Hits Allowed
Pirates P Carmen Mlodzinski — 1.5 Walks Allowed
Red Sox 3B Alex Bregman — 1.5 Total Bases
Orioles SS Gunnar Henderson —1.5 Hits+Runs+RBI
Home Run Pick: Braves 1B Matt Olson

Orioles P Cade Povich — 4.5 Hits Allowed (Goblin)

Time: 6:35 p.m. ET

Orioles P Cade Povich has allowed six or more hits in three of last four starts.
The Yankees are third in hits per game (8.33).
According to Baseball Savant, Povich is under the 20th percentile in several categories including whiff rate (14th), expected ERA (18th), and pitching run value (2nd).
He has faced just four Yankees, and two (Aaron Judge and Anthony Volpe) have recorded a hit.

Note: Goblin picks reduce your payout on PrizePicks, as they are easier projections to hit.

💰 Use PrizePicks Promo Code "Playbook": Claim FREE $50 with your first $5+ Lineup

‍

Pirates P Carmen Mlodzinski — 1.5 Walks Allowed (Goblin)

Time: 6:40 p.m. ET

Pirates P Carmen Mlodzinski has a dreadful 31.6% walk rate against the Cubs in 19 plate appearances.
Mlodzinski has walked at least two batters in four of five starts in 2025.
The Cubs rank fourth in walk rate this season (10.2%) as a team.

Note: Goblin picks reduce your payout on PrizePicks, as they are easier projections to hit.

Red Sox 3B Alex Bregman — 1.5 Total Bases (Demon)

Time: 7:07 p.m. ET

Red Sox 3B Alex Bregman has 2+ total bases in four of his last six games.
He has the four most hits (10) since April 22nd.
He has the second most doubles (4) since April 22nd
11 of 21 hits from Bregman at Rogers Centre have been for extra bases and has a career .777 OPS at the stadium.

Note: Demon picks add a payout boost to your lineup on PrizePicks, as they are more difficult projections to hit.

Orioles SS Gunnar Henderson —1.5 Hits+Runs+RBI (Goblin)

Time: 6:35 p.m. ET

Orioles SS Gunnar Henderson has cleared this projection in three of the last four games.
He has a hit in five consecutive games, including back-to-back against the Yankees
He is a career 3-for-5 with a home run against Yankees P Carlos Carrasco.
He has a career .826 OPS against the Yankees.

Note: Goblin picks reduce your payout on PrizePicks, as they are easier projections to hit.

Home Run Pick: Braves 1B Matt Olson

Time: 6:35 p.m. ET

Braves 1B Matt Olson has four home runs this season, all against right-handed pitchers.
Olson’s opposing starting pitcher, right-hander Chase Dollander, has allowed eight home runs in four starts this season — five have come vs. left-handed hitters.
Dollander is surrendering a 36.7% hard-hit, 33.3% HR per fly ball, and 4.77 xFIP to left-handed hitters
The Rockies bullpen hasn’t been any better, as they allowed 12 home runs, the fourth-most in the league.
Olson is starting to get hot, and is 4-for-9 in this series.
Braves vs. Rockies will be played in Coors Field, the friendliest park for home-run hitters.

Note: Demon picks add a payout boost to your lineup on PrizePicks, as they are more difficult projections to hit.

Cash in on MLB DFS Today on PrizePicks

With all day baseball on Wednesday, there are a lot of fantastic games on the MLB DFS slate, so there’s no better time to participate in the action on PrizePicks.

Just build your MLB Lineup on PrizePicks and win real money if your picks are correct.

All you need to do is pick More or Less on at least two player projections — like hits or pitcher strikeouts — to win real cash.

Whether you go with demons or goblins, there’s always real money sports action waiting for you on PrizePicks. Stay locked in on the Playbook all season long for MLB player picks every day.