The Wednesday MLB slate showcases a full slate of 15 games, including a key American League matchup. Below, we'll highlight the top MLB DFS picks for tonight's five MLB games. Headlining the MLB slate, the Boston Red Sox (64-51) battle the Kansas City Royals (56-58) at Fenway Park at 7:10 p.m. ET as Boston seeks a series sweep.
Welcome to the top MLB DFS picks for Wednesday, August 6, as we’ll break down today’s MLB games and give you the best MLB DFS picks for PrizePicks for August 6, including pitcher strikeout projections for Jose Quintana and George Kirby, and hitter projections to target today.
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Let’s break down some of the best MLB picks to target for the Wednesday MLB DFS slate on PrizePicks.
MLB DFS Picks on PrizePicks: Wednesday, August 6
Here are some of the top MLB DFS picks and predictions on PrizePicks today. Use this analysis to help you build a stacked MLB Lineup on PrizePicks for Wednesday, August 6. Click each MLB pick to read more.
- Athletics 1B Nick Kurtz — 1.5 Total Bases
- Brewers LF Christian Yelich — 5.5 Hitter Fantasy Score
- Brewers P Jose Quintana — 4 Strikeouts
- Mariners P George Kirby — 6 Strikeouts
Athletics 1B Nick Kurtz — 1.5 Total Bases

- Athletics 1B Nick Kurtz continues to put up impressive numbers after going 3-for-4 with four runs scored in Tuesday’s blowout of Washington.
- Since his 6-for-6 performance with four home runs at Houston on July 25, Kurtz has gone more than this projection in three of the last eight games.
- Kurtz has not gone deep in the last eight games since his four home run output against the Astros.
- The AL Rookie of the Year favorite is racking up an xSLG of .585 (98th percentile), 19.6% barrel rate (98th percentile), and xwOBA of .395 (96th percentile).
- Since July 5, Kurtz has posted 13 multi-hit games, including eight times away from Sacramento.
Brewers LF Christian Yelich — 5.5 Hitter Fantasy Score

- Brewers LF Christian Yelich has been on fire through five August games. Yelich is batting .381, including three multi-hit performances.
- Yelich has reached double-digits on his fantasy score in four of the last five contests, including 28 points against Washington last Saturday.
- Before Yelich’s recent hot streak, he closed out July in a 3-for-21 slump with three runs batted in.
- Yelich owns a .253 xBA, which is the second-lowest of his career, and is below the 55th percentile in MLB in xBA, xWOBA, and xSLG.
- In three career at-bats against Braves P Spencer Strider, Yelich has struck out twice and picked up one hit.
Brewers P Jose Quintana — 4 Strikeouts

- Brewers P Jose Quintana has compiled at least four strikeouts in three of his past four trips to the mound.
- Quintana owns a 15.9% strikeout rate, which is not only the lowest of his career, but also ranks in only the eighth percentile in MLB.
- The top strikeout victim for Quintana on the Braves is 1B Matt Olson, who has struck out nine times in 24 at-bats.
- Five of the last six opposing left-handed starting pitchers facing Atlanta have picked up three strikeouts or fewer.
- In seven of nine road starts this season, Quintana has finished with four of fewer strikeouts.
Mariners P George Kirby — 6 Strikeouts

- Mariners P George Kirby has struck out at least six batters in four of the last five trips to the mound.
- Kirby didn’t face the White Sox earlier this season, but posted seven K’s in a 10-0 shutout at Chicago last July.
- Kirby’s strikeout rate sits at 25.2% this season, the best of his career.
- Prior to Tuesday night, opposing starting pitchers facing Chicago struck out five batters or fewer in 13 straight games. Mariners P Bryan Woo sat down nine batters via the strikeout last night.
- In only three of 13 starts this season Kirby has managed at least seven strikeouts. Out of seven home outings, Kirby has reached the seven strikeout mark once with nine K’s against Pittsburgh on July 6.
Make MLB DFS Picks on PrizePicks
There’s exciting action on Wednesday’s MLB slate during the day, capped off by five night games. With 15 MLB games on tap, now is time to build your MLB Lineup on PrizePicks.
Just pick More or Less at least two MLB player stat projections to build your Lineup on PrizePicks. Use the player projections above to build your Lineups around, or use a 6-Pick Lineup to reach up to 2000x payouts.
Check out the Playbook for more MLB DFS picks and analysis all the way through the season.